Variant · Snv
PC NM_001040716.2(PC):c.616G>T (p.Val206Leu)
CI-VAR-00032007Explore in graph →p.Val206LeuNM_001040716.2:c.616G>TClinVar 203920 rs147945506
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 203920 | Conflicting classifications of pathogenicity | criteria provided, conflicting classifications | 1 | Pyruvate carboxylase deficiency; Clear cell carcinoma of kidney; Thyroid cancer, nonmedullary, 1; Cholangiocarcinoma; Malignant tumor of urinary bladder; Nonpapillary renal cell carcinoma | germline | 6 | Feb 01, 2026 | clinvar |