Gene
PC
pyruvate carboxylase
Explore in graph →CI-GENE-00018986HGNC:8636 ENSG00000173599 NCBI 5091 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (7)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 33067607
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Lymphoma Cell Lines (MSK, Blood 2020) lymphoma_cellline_msk_2020 | unmapped | Ssm | 3 | 34 | 8.8% | 78 | cbioportal |
| Esophagogastric Cancer (MSK, Clin Cancer Res 2023) egc_trap_ccr_msk_2023 | Gastroesophageal Junction Adenocarcinoma | Ssm | 5 | 64 | 7.8% | 161 | cbioportal |
| Classical Hodgkins Lymphoma (SCCC, Blood Cancer Discov 2023) chl_sccc_2023 | Classic Hodgkin Lymphoma | Ssm | 4 | 61 | 6.6% | 99 | cbioportal |
| Pancreatic Neuroendocrine Tumors (Multi-Institute, Nature 2017) panet_arcnet_2017 | Pancreatic Neuroendocrine Tumor | Ssm | 2 | 98 | 2% | 126 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.