MYH11 NM_001040113.2(MYH11):c.654+1G>A

CI-VAR-00031972Explore in graph →NM_001040113.2:c.654+1G>AClinVar 201100 rs770424951

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
201100	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Familial thoracic aortic aneurysm and aortic dissection; Aortic aneurysm, familial thoracic 4; Visceral myopathy 2; Megacystis-microcolon-intestinal hypoperistalsis syndrome 2; Familial cancer of breast	germline	6	Dec 12, 2025	clinvar