MYH11 NM_002474.3(MYH11):c.1017C>T (p.Ser339=)

CI-VAR-00031889Explore in graph →p.Ser339=NM_002474.3:c.1017C>TClinVar 199079 rs112161189

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
199079	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Cardiovascular phenotype; Familial thoracic aortic aneurysm and aortic dissection; Aortic aneurysm, familial thoracic 4; MYH11-related disorder; Colorectal cancer	germline	12	Jan 20, 2026	clinvar