Variant · Deletion
ADAM17 NM_003183.6(ADAM17):c.362-9del
CI-VAR-00193432Explore in graph →NM_003183.6:c.362-9delClinVar 1154607 rs769247529
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 1154607 | Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Inflammatory skin and bowel disease, neonatal, 1; ADAM17-related disorder; Nonpapillary renal cell carcinoma | germline | 4 | Nov 26, 2025 | clinvar |