NRAS NM_002524.5(NRAS):c.173C>T (p.Thr58Ile)

CI-VAR-00182969Explore in graph →p.Thr58IleNM_002524.5:c.173C>TClinVar 1070042 rs2101742052

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
1070042	Pathogenic	reviewed by expert panel	3	RASopathy; Colorectal cancer; Noonan syndrome and Noonan-related syndrome; Noonan syndrome 1; Noonan syndrome	germline	7	Dec 03, 2024	clinvar