Variant · Fusion
ABL1 Fusion
CI-VAR-00001310Explore in graph →CIViC 3287
Curated evidence
Evidence by cancer (7 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 31935290
- Run
- ING-CIVIC-20260908-000001
| Molecular profile | Therapy | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| Acute Lymphoblastic Leukemia2 | ||||||||
| ADAD2-AS1::ABL1 Fusion | (diagnostic) | Diagnostic | B | Supports Positive | 3 | rejected | EID9156SFPQ-ABL1fusion was identified in Ph-like ALL PMID 31935290 · Harvey et al., 2020 · Open in CIViC | civic |
| ADAD2-AS1::ABL1 Fusion | (prognostic) | Prognostic | B | Supports Poor Outcome | 3 | rejected | EID9157patients with Ph-like ALL had an inferior 5-year event-free survival compared with patients with non–Ph-like ALL (22.5% [95% CI, 14.9% to 29.3%; n = 155] v 49.3% [95% CI, 42.8% to 56.2%; n = 247], res… (full text at CIViC) PMID 27870571 · Roberts et al., 2017 · Open in CIViC | civic |
| B Lymphoblastic Leukemia/Lymphoma | ||||||||
ClinVar
Clinical significance (0)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
Data not yet available