Loading clinical trials…
Loading clinical trials…
Clinical trials
Studies registered on ClinicalTrials.gov whose conditions were reconciled to the cancer taxonomy. Status and phase are as posted by the registrant.
901 studies match
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01871805 | A Study of Alectinib (CH5424802/RO5424802) in Participants With Anaplastic Lymphoma Kinase (ALK)-Rearranged Non-Small Cell Lung Cancer (NSCLC) | completed | Phase 1 / Phase 2 | 134 | Hoffmann-La RocheINDUSTRY | 2 | Aug 21, 2018 | clinicaltrials |
| NCT03330990 | Evaluate the Effect of Entrectinib on the Pharmacokinetics of Midazolam in Cancer Patients | completed | Phase 1 | 15 | Hoffmann-La RocheINDUSTRY | 1 | Aug 21, 2018 | clinicaltrials |
| NCT00718549 | A Study to Assess the Effect of Maintenance Treatment With Rituximab Versus No Treatment in Participants With Progressive B-Cell Chronic Lymphocytic Leukemia (CLL) | completed | Phase 3 | 128 | Hoffmann-La RocheINDUSTRY | 2 | Aug 20, 2018 | clinicaltrials |
| NCT01026142 | A Study of a Combination of Trastuzumab and Capecitabine With or Without Pertuzumab in Patients With HER2-positive Metastatic Breast Cancer (PHEREXA) | completed | Phase 3 | 452 | Hoffmann-La RocheINDUSTRY | 23 | Aug 14, 2018 | clinicaltrials |
| NCT01461057 | A Study of Pertuzumab in Combination With Trastuzumab and Chemotherapy in Patients With HER2-Positive Advanced Gastric Cancer(JOSHUA) | completed | Phase 2 | 30 | Hoffmann-La RocheINDUSTRY | 8 | Aug 9, 2018 | clinicaltrials |
| NCT00577109 | A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Previously Untreated Metastatic Colorectal Cancer. | withdrawn | Phase 2 | 0 | Hoffmann-La RocheINDUSTRY | 1 | Jul 31, 2018 | clinicaltrials |
| NCT01712347 | An Observational Study of First-Line Bevacizumab (Avastin) With Fluoropyrimidine-Based Chemotherapy in Participants With Metastatic Colorectal Cancer | completed | — | 351 | Hoffmann-La RocheINDUSTRY | 1 | Jul 31, 2018 | clinicaltrials |
| NCT02287597 | An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Colorectal Cancer: Continued Avastin Plus Chemotherapy After First Progression in Clinical Practice | completed | — | 90 | Hoffmann-La RocheINDUSTRY | 1 | Jul 30, 2018 | clinicaltrials |
| NCT01782690 | An Observational Study of Erlotinib Plus Gemcitabine in Patients With Metastatic Pancreatic Cancer | completed | — | 338 | Hoffmann-La RocheINDUSTRY | 1 | Jul 23, 2018 | clinicaltrials |
| NCT01609023 | A Study of Rituximab (MabThera) in Combination With Chemotherapy in Participants With CD20-Positive B-Cell Chronic Lymphocytic Leukemia(CaLLypso) | completed | — | 67 | Hoffmann-La RocheINDUSTRY | 1 | Jun 26, 2018 | clinicaltrials |
| NCT01220934 | An Observational Study of Herceptin (Trastuzumab) in Patients With HER2-positive Advanced Gastric Cancer | completed | — | 443 | Hoffmann-La RocheINDUSTRY | 1 | Jun 20, 2018 | clinicaltrials |
| NCT01990248 | An Observational Safety Study in Zelboraf (Vemurafenib)-Treated Patients With BRAF-V600 Mutation-Positive Unresectable or Metastatic Melanoma (ZeSS) | completed | — | 339 | Hoffmann-La RocheINDUSTRY | 10 | Jun 19, 2018 | clinicaltrials |
| NCT02738970 | A Dose-Finding Study of Pertuzumab (Perjeta) in Combination With Trastuzumab (Herceptin) in Healthy Male Participants and Women With Early Breast Cancer (EBC) | completed | Phase 1 | 88 | Hoffmann-La RocheINDUSTRY | 1 | Jun 12, 2018 | clinicaltrials |
| NCT02760797 | A Study of Emactuzumab and RO7009789 Administered in Combination in Participants With Advanced Solid Tumors | completed | Phase 1 | 38 | Hoffmann-La RocheINDUSTRY | 3 | May 22, 2018 | clinicaltrials |
| NCT02098967 | A Study of the Safety and Pharmacokinetics of RO6839921, An MDM2 Antagonist, in Patients With Advanced Cancers, Including Acute Myeloid Leukemia. | completed | Phase 1 | 68 | Hoffmann-La RocheINDUSTRY | 2 | May 17, 2018 | clinicaltrials |
| NCT01506167 | An Observational Study of Avastin (Bevacizumab) in Patients With Metastatic Colorectal Cancer (ACORN) | completed | — | 719 | Hoffmann-La RocheINDUSTRY | 1 | May 14, 2018 | clinicaltrials |
| NCT01893268 | An Observational Study of Avastin (Bevacizumab) in Elderly Patients With Non-Squamous Non-Small Cell Lung Cancer in Clinical Practice | completed | — | 279 | Hoffmann-La RocheINDUSTRY | 1 | May 14, 2018 | clinicaltrials |
| NCT01860638 | A Comparison of Continuous Bevacizumab (Avastin) Treatment or Placebo in Addition to Lomustine Followed by Standard of Care After Disease Progression in Participants With Glioblastoma | completed | Phase 2 | 296 | Hoffmann-La RocheINDUSTRY | 15 | Apr 30, 2018 | clinicaltrials |
| NCT01263704 | A Study of MabThera/Rituxan (Rituximab) in Combination With Fludarabine And Cyclophosphamide as Primary Therapy in Elderly Patients With Chronic Lymphocytic Leukemia | completed | Phase 2 | 42 | Hoffmann-La RocheINDUSTRY | 1 | Apr 23, 2018 | clinicaltrials |
| NCT02383576 | Retrospective Data Collection: Post Study Treatment Anticancer Therapy From IMELDA MO22223 | completed | — | 185 | Hoffmann-La RocheINDUSTRY | 6 | Apr 13, 2018 | clinicaltrials |
| NCT00559845 | A Study of Avastin (Bevacizumab) in Patients With Inflammatory or Locally Advanced Breast Cancer | completed | Phase 2 | 56 | Hoffmann-La RocheINDUSTRY | 1 | Apr 9, 2018 | clinicaltrials |
| NCT02654379 | Observational Study Evaluating Rituximab Use and Use of the Patient Alert Card in Participants Receiving Rituximab Infusion for a Non-Oncology Indication at Infusion Centers in Europe | completed | — | 1,408 | Hoffmann-La RocheINDUSTRY | 5 | Apr 9, 2018 | clinicaltrials |
| NCT03369964 | A Study of Atezolizumab in Combination With an Immunotherapy Agent Investigated With or Without Anti-Cd20 Therapy in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma | withdrawn | Phase 1 | 0 | Hoffmann-La RocheINDUSTRY | 1 | Apr 5, 2018 | clinicaltrials |
| NCT02558140 | A Dose Escalation Study of RO6874813 in Participants With Locally Advanced or Metastatic Solid Tumors | completed | Phase 1 | 120 | Hoffmann-La RocheINDUSTRY | 3 | Apr 4, 2018 | clinicaltrials |
| NCT00885755 | A Study of Herceptin (Trastuzumab)and Biomarkers in Patients With HER2-Positive Metastatic Breast Cancer | completed | Phase 2 | 33 | Hoffmann-La RocheINDUSTRY | 4 | Mar 29, 2018 | clinicaltrials |
| NCT01839500 | A Non-Interventional Study of Treatment Pattern and Clinical Outcomes in Chinese Participants With Gastric Cancer(EVIDENCE) | completed | — | 1,600 | Hoffmann-La RocheINDUSTRY | 1 | Mar 29, 2018 | clinicaltrials |
| NCT01094184 | A Study of Bevacizumab With Taxane Therapy in Participants With Triple Negative Breast Cancer(BATMAN) | completed | Phase 4 | 49 | Hoffmann-La RocheINDUSTRY | 1 | Mar 22, 2018 | clinicaltrials |
| NCT01271010 | A Study of Rituximab in Combination With Fludarabine and Cyclophosphamide in Participants With Chronic Lymphocytic Leukemia and Favorable Somatic Status | terminated | Phase 4 | 89 | Hoffmann-La RocheINDUSTRY | 1 | Mar 20, 2018 | clinicaltrials |
| NCT01142778 | A Study of Bevacizumab Added to Trastuzumab Plus Docetaxel in the Neoadjuvant Setting in Participants With Early Stage HER2-Positive Breast Cancer(AVATAXHER) | completed | Phase 2 | 152 | Hoffmann-La RocheINDUSTRY | 1 | Mar 16, 2018 | clinicaltrials |
| NCT01494688 | A Study of RO5509554 as Monotherapy and in Combination With Paclitaxel in Participants With Advanced Solid Tumors | completed | Phase 1 | 217 | Hoffmann-La RocheINDUSTRY | 2 | Mar 16, 2018 | clinicaltrials |
| NCT03071848 | A Study to Evaluate Safety and Effectiveness of Bevacizumab in Combination With Paclitaxel and Cisplatin/Carboplatin or Toptecan in Participants With Advanced Cervical Cancer | completed | — | 84 | Hoffmann-La RocheINDUSTRY | 1 | Mar 16, 2018 | clinicaltrials |
| NCT02004106 | A Study to Evaluate Safety, Pharmacokinetics, and Efficacy of RO6895882 in Participants With Advanced and/or Metastatic Solid Tumors | completed | Phase 1 | 110 | Hoffmann-La RocheINDUSTRY | 8 | Mar 6, 2018 | clinicaltrials |
| NCT00360347 | A Study of Mircera in Anemic Patients With Multiple Myeloma | completed | Phase 1 / Phase 2 | — | Hoffmann-La RocheINDUSTRY | 2 | Mar 1, 2018 | clinicaltrials |
| NCT01618747 | An Observational Study of Avastin (Bevacizumab) in Patients With Glioblastoma Multiforme in First or Second Relapse | completed | — | 20 | Hoffmann-La RocheINDUSTRY | 1 | Feb 28, 2018 | clinicaltrials |
| NCT02438644 | Observational Study of Vismodegib (Erivedge) in Patients Treated in Argentina | completed | — | 75 | Hoffmann-La RocheINDUSTRY | 0 | Feb 26, 2018 | clinicaltrials |
| NCT02093000 | A Study Examining Maintenance Bevacizumab (Avastin®) Monotherapy in Participants With Advanced Lung Adenocarcinoma | completed | — | 201 | Hoffmann-La RocheINDUSTRY | 1 | Feb 23, 2018 | clinicaltrials |
| NCT01767623 | A Study of The Impact of Severe Hepatic Impairment on the Pharmacokinetics and Safety of Vemurafenib in BRAF V600 Mutation-Positive Cancer Participants | completed | Phase 1 | 8 | Hoffmann-La RocheINDUSTRY | 7 | Feb 13, 2018 | clinicaltrials |
| NCT01632228 | A Study of Onartuzumab (MetMAb) in Combination With Bevacizumab Compared to Bevacizumab Alone or Onartuzumab Monotherapy in Participants With Recurrent Glioblastoma | completed | Phase 2 | 135 | Hoffmann-La RocheINDUSTRY | 8 | Feb 5, 2018 | clinicaltrials |
| NCT02831842 | A Real World Study to Evaluate Effectiveness of Avastin (Bevacizumab) for First Line Treatment of Patients With Metastatic Colorectal Cancer and Known KRAS Status | completed | — | 4,278 | Hoffmann-La RocheINDUSTRY | 0 | Jan 26, 2018 | clinicaltrials |
| NCT01152606 | A Study of Cardiac Safety in Patients With HER2 Positive Early Breast Cancer Treated With Herceptin | completed | — | 3,942 | Hoffmann-La RocheINDUSTRY | 9 | Jan 25, 2018 | clinicaltrials |
| NCT00950300 | A Study to Compare Subcutaneous (SC) Versus Intravenous (IV) Administration of Herceptin (Trastuzumab) in Women With Human Epidermal Growth Factor Receptor (HER) 2-Positive Early Breast Cancer | completed | Phase 3 | 596 | Hoffmann-La RocheINDUSTRY | 26 | Jan 23, 2018 | clinicaltrials |
| NCT01378962 | A Study of Tarceva (Erlotinib) in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (TRIGGER) | completed | Phase 2 | 50 | Hoffmann-La RocheINDUSTRY | 1 | Jan 23, 2018 | clinicaltrials |
| NCT01724021 | A Study of Participant Preference With Subcutaneous Versus Intravenous MabThera/Rituxan in Participants With CD20+ Diffuse Large B-Cell Lymphoma or CD20+ Follicular Non-Hodgkin's Lymphoma Grades 1, 2 or 3a | completed | Phase 3 | 743 | Hoffmann-La RocheINDUSTRY | 32 | Jan 23, 2018 | clinicaltrials |
| NCT01987362 | A Two Part Study of RO6870810. Dose-Escalation Study in Participants With Advanced Solid Tumors and Expansion Study in Participants With Selected Malignancies | completed | Phase 1 | 52 | Hoffmann-La RocheINDUSTRY | 1 | Jan 5, 2018 | clinicaltrials |
| NCT01684865 | An Observational Study of First-Line Maintenance Rituximab (MabThera/Rituxan) in Participants With Follicular Non-Hodgkin's Lymphoma | completed | — | 22 | Hoffmann-La RocheINDUSTRY | 1 | Dec 29, 2017 | clinicaltrials |
| NCT01307397 | A Study of Vemurafenib in Participants With Metastatic Melanoma | completed | Phase 3 | 3,219 | Hoffmann-La RocheINDUSTRY | 44 | Dec 18, 2017 | clinicaltrials |
Data updated 24 days agoSource updated unknownsource: clinicaltrials