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Clinical trials
Studies registered on ClinicalTrials.gov whose conditions were reconciled to the cancer taxonomy. Status and phase are as posted by the registrant.
2,114 studies match
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01853228 | A Study of Decitabine (DACOGEN) in Sequential Administration With Cytarabine in Children With Relapsed or Refractory Acute Myeloid Leukemia | terminated | Phase 1 / Phase 2 | 17 | Janssen Research & Development, LLCINDUSTRY | 7 | Jun 17, 2019 | clinicaltrials |
| NCT01047969 | Avoiding Surgery in Rectal Cancer After Pre-Operative Therapy | unknown | Phase 2 | 99 | Royal Marsden NHS Foundation TrustOTHER | 1 | Jun 13, 2019 |
| NCT01367665 | STEVIE: A Study of Vismodegib in Patients With Locally Advanced or Metastatic Basal Cell Carcinoma | completed | Phase 2 | 1,232 | Hoffmann-La RocheINDUSTRY | 37 | Jun 6, 2019 | clinicaltrials |
| NCT02546544 | Eurosarc Trial of Linsitinib in Advanced Ewing Sarcoma(LINES) | completed | Phase 2 | 16 | University of OxfordOTHER | 5 | Jun 3, 2019 | clinicaltrials |
| NCT01610869 | Low Dose Cyclophosphamide +/-- Nintedanib in Advanced Ovarian Cancer(METRO-BIBF) | completed | Phase 2 | 117 | University College, LondonOTHER | 1 | May 29, 2019 | clinicaltrials |
| NCT01601184 | Study of Vismodegib in Combination With Temozolomide Versus Temozolomide Alone in Patients With Medulloblastomas With an Activation of the Sonic Hedgehog Pathway | terminated | Phase 1 / Phase 2 | 24 | Centre Leon BerardOTHER | 4 | May 21, 2019 | clinicaltrials |
| NCT00647530 | Fluorouracil and Oxaliplatin With or Without Panitumumab In Treating Patients With High-Risk Colon Cancer That Can Be Removed by Surgery(FOxTROT) | unknown | Phase 2 / Phase 3 | 1,053 | University of BirminghamOTHER | 1 | May 17, 2019 | clinicaltrials |
| NCT01191892 | Carboplatin and Gemcitabine Hydrochloride With or Without Vandetanib as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Urinary Tract Cancer | completed | Phase 2 | 82 | Cardiff UniversityOTHER | 1 | May 16, 2019 | clinicaltrials |
| NCT00219557 | AG-013736 In Combination With Gemcitabine Versus Gemcitabine Alone For Patients With Metastatic Pancreatic Cancer | completed | Phase 2 | 111 | PfizerINDUSTRY | 8 | May 14, 2019 | clinicaltrials |
| NCT01556841 | The Activity of TroVax® Versus Placebo in Relapsed Asymptomatic Ovarian Cancer(TRIOC) | completed | Phase 2 | 94 | University College, LondonOTHER | 1 | May 9, 2019 | clinicaltrials |
| NCT01230996 | Dose Escalation Study of Simultaneous Boost Intensity-Modulated Radiotherapy for Locally Advanced Cervical Cancer(DEPICT) | completed | Phase 1 / Phase 2 | 22 | Barts & The London NHS TrustOTHER | 1 | Apr 24, 2019 | clinicaltrials |
| NCT01517724 | Bortezomib Consolidation Trial(BCT) | completed | Phase 2 | 40 | University College, LondonOTHER | 1 | Apr 17, 2019 | clinicaltrials |
| NCT01381874 | A Study of Abiraterone Acetate Plus Prednisone With or Without Exemestane in Postmenopausal Women With Estrogen Receptor-Positive (ER+) Metastatic Breast Cancer Progressing After Letrozole or Anastrozole Therapy | completed | Phase 2 | 297 | Janssen Research & Development, LLCINDUSTRY | 12 | Apr 11, 2019 | clinicaltrials |
| NCT03081481 | Intraprostatic PRX302 Injection to Treat Localised Prostate Cancer | completed | Phase 2 | 38 | Sophiris Bio CorpINDUSTRY | 2 | Apr 10, 2019 | clinicaltrials |
| NCT01521611 | Targeted Radiotherapy in HSCT for Poor Risk Haematological Malignancy | completed | Phase 1 / Phase 2 | 62 | University Hospital Southampton NHS Foundation TrustOTHER | 1 | Apr 8, 2019 | clinicaltrials |
| NCT02632786 | The PRONTO Study, a Global Phase 2b Study of NEOD001 in Previously Treated Subjects With Light Chain (AL) Amyloidosis(PRONTO) | completed | Phase 2 | 129 | Prothena Biosciences Ltd.INDUSTRY | 10 | Apr 5, 2019 | clinicaltrials |
| NCT01685138 | LDK378 in Crizotinib naïve Adult Patients With ALK-activated Non-small Cell Lung Cancer | completed | Phase 2 | 124 | Novartis PharmaceuticalsINDUSTRY | 18 | Mar 26, 2019 | clinicaltrials |
| NCT02048488 | A Phase I/IIa Open-Label, Dose Escalation and Cohort Expansion Trial of Oral TSR-011 in Patients With Advanced Solid Tumors and Lymphomas | completed | Phase 1 / Phase 2 | 72 | Tesaro, Inc.INDUSTRY | 5 | Mar 26, 2019 | clinicaltrials |
| NCT03154047 | Study in Subjects With Light Chain (AL) Amyloidosis | terminated | Phase 2 | 80 | Prothena Biosciences Ltd.INDUSTRY | 10 | Mar 26, 2019 | clinicaltrials |
| NCT02723877 | PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO) | completed | Phase 1 / Phase 2 | 41 | PIQUR Therapeutics AGINDUSTRY | 2 | Mar 22, 2019 | clinicaltrials |
| NCT02472145 | An Efficacy and Safety Study of Decitabine (DACOGEN) Plus Talacotuzumab (JNJ-56022473; Anti CD123) Versus Decitabine (DACOGEN) Alone in Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy | completed | Phase 2 / Phase 3 | 326 | Janssen Research & Development, LLCINDUSTRY | 14 | Mar 19, 2019 | clinicaltrials |
| NCT01907100 | Nintedanib (BIBF 1120) in Mesothelioma | terminated | Phase 2 / Phase 3 | 545 | Boehringer IngelheimINDUSTRY | 27 | Mar 18, 2019 | clinicaltrials |
| NCT01548677 | Efficacy Study of Herceptin to Treat HER2-negative CTC Breast Cancer(TREAT-CTC) | completed | Phase 2 | 1,317 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 4 | Mar 13, 2019 | clinicaltrials |
| NCT01948180 | Cellular Immunotherapy Treatment Antigen-Directed for EBV Lymphoma(CITADEL) | terminated | Phase 2 | 15 | Cell Medica LtdINDUSTRY | 4 | Mar 13, 2019 | clinicaltrials |
| NCT01685255 | A Phase 2 Study of the IDO Inhibitor Epacadostat Versus Tamoxifen for Subjects With Biochemical-recurrent-only EOC, PPC or FTC Following Complete Remission With First-line Chemotherapy | terminated | Phase 2 | 83 | Incyte CorporationINDUSTRY | 6 | Mar 11, 2019 | clinicaltrials |
| NCT01997333 | Study of Glembatumumab Vedotin (CDX-011) in Patients With Metastatic, gpNMB Over-Expressing, Triple Negative Breast Cancer(METRIC) | completed | Phase 2 | 327 | Celldex TherapeuticsINDUSTRY | 9 | Mar 8, 2019 | clinicaltrials |
| NCT01164189 | Bevacizumab in Recurrent Grade II and III Glioma(TAVAREC) | completed | Phase 2 | 155 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 8 | Feb 28, 2019 | clinicaltrials |
| NCT00920556 | A Clinical Study to Assess the Safety and Activity of SRT501 Alone or in Combination With Bortezomib in Patients With Multiple Myeloma | terminated | Phase 2 | 24 | Sirtris, a GSK CompanyINDUSTRY | 2 | Feb 27, 2019 | clinicaltrials |
| NCT01136733 | A Study of E7080 Alone, and in Combination With Everolimus in Subjects With Unresectable Advanced or Metastatic Renal Cell Carcinoma Following One Prior Vascular Endothelial Growth Factor (VEGF)-Targeted Treatment | completed | Phase 1 / Phase 2 | 173 | Eisai Inc.INDUSTRY | 5 | Feb 27, 2019 | clinicaltrials |
| NCT01881230 | Evaluate Risk/Benefit of Nab Paclitaxel in Combination With Gemcitabine and Carboplatin Compared to Gemcitabine and Carboplatin in Triple Negative Metastatic Breast Cancer (or Metastatic Triple Negative Breast Cancer)(tnAcity) | completed | Phase 2 / Phase 3 | 191 | CelgeneINDUSTRY | 12 | Feb 21, 2019 | clinicaltrials |
| NCT01752569 | A Study of Selumetinib in Patients With Kaposi's Sarcoma(SCART) | terminated | Phase 1 / Phase 2 | 19 | Sheffield Teaching Hospitals NHS Foundation TrustOTHER | 1 | Feb 20, 2019 | clinicaltrials |
| NCT01240525 | Donor Lymphocyte Infusion After Stem Cell Transplant in Treating Patients With Haematological Cancers(ProT4) | unknown | Phase 2 | 114 | University College, LondonOTHER | 1 | Feb 12, 2019 | clinicaltrials |
| NCT03812796 | Epigenetic Modulation of the immunE Response in GastrointEstinal Cancers (EMERGE)(EMERGE) | unknown | Phase 2 | 75 | Royal Marsden NHS Foundation TrustOTHER | 1 | Feb 5, 2019 | clinicaltrials |
| NCT02012920 | A Study to Evaluate Oral VT-464 in Patients With Castration-Resistant Prostate Cancer | completed | Phase 2 | 200 | Innocrin PharmaceuticalINDUSTRY | 4 | Feb 1, 2019 | clinicaltrials |
| NCT02275403 | Standard Care Alone or With Acupuncture for CIPN in Breast Cancer and Multiple Myeloma(ACUFOCIN) | completed | Phase 2 | 120 | The Christie NHS Foundation TrustOTHER | 1 | Jan 31, 2019 | clinicaltrials |
| NCT00910091 | The Study of Oral Steroid Sulphatase Inhibitor BN83495 Versus Megestrol Acetate (MA) in Women With Advanced or Recurrent Endometrial Cancer | completed | Phase 2 | 73 | IpsenINDUSTRY | 12 | Jan 30, 2019 | clinicaltrials |
| NCT02409212 | Exercise Training as a Novel Primary Therapy for Men With Localised Prostate Cancer(PANTERA) | completed | Phase 2 | 50 | Sheffield Teaching Hospitals NHS Foundation TrustOTHER | 1 | Jan 30, 2019 | clinicaltrials |
| NCT00688623 | RAMSETE: RAD001 in Advanced and Metastatic Silent Neuro-endocrine Tumors in Europe(RAMSETE/CDE16) | completed | Phase 2 | 73 | Novartis PharmaceuticalsINDUSTRY | 8 | Jan 25, 2019 | clinicaltrials |
| NCT01279252 | CLL Empirical Antibiotic Regimen(CLEAR) | completed | Phase 2 | 71 | King's College Hospital NHS TrustOTHER | 1 | Jan 25, 2019 | clinicaltrials |
| NCT02272816 | Carboplatin AUC-10 With Early PET Scanning in Metastatic Seminoma(Car-PET) | completed | Phase 2 | 48 | Barts & The London NHS TrustOTHER | 1 | Jan 25, 2019 | clinicaltrials |
| NCT01337401 | A Trial of Cediranib in the Treatment of Patients With Alveolar Soft Part Sarcoma (CASPS)(CASPS) | unknown | Phase 2 | 36 | Institute of Cancer Research, United KingdomOTHER | 3 | Jan 24, 2019 | clinicaltrials |
| NCT03182634 | The UK Plasma Based Molecular Profiling of Advanced Breast Cancer to Inform Therapeutic CHoices (plasmaMATCH) Trial(plasmaMATCH) | unknown | Phase 2 | 1,150 | Institute of Cancer Research, United KingdomOTHER | 1 | Jan 22, 2019 | clinicaltrials |
| NCT01415011 | Efficacy and Safety Study of Afatinib to Treat Lung Cancer Patients(TIMELY) | completed | Phase 2 | 39 | University College, LondonOTHER | 1 | Jan 15, 2019 | clinicaltrials |
| NCT02976883 | [18F]HX4 PET/CT Imaging for Detection of Hypoxia(OXYPET) | completed | Phase 2 | 8 | Nottingham University Hospitals NHS TrustOTHER | 1 | Jan 11, 2019 | clinicaltrials |
| NCT01210495 | Axitinib For The Treatment Of Advanced Hepatocellular Carcinoma | completed | Phase 2 | 224 | PfizerINDUSTRY | 13 | Jan 9, 2019 | clinicaltrials |
| NCT01420081 | A Study Of Two Dual PI3K/mTOR Inhibitors, PF-04691502 And PF-05212384 In Patients With Recurrent Endometrial Cancer | terminated | Phase 2 | 67 | PfizerINDUSTRY | 8 | Jan 8, 2019 | clinicaltrials |
| NCT01743469 | A Study With Tasquinimod Treating Patients With Hepatocellular, Ovarian, Renal Cell and Gastric Cancers | completed | Phase 2 | 201 | IpsenINDUSTRY | 5 | Jan 8, 2019 | clinicaltrials |
| NCT01846416 | A Study of Atezolizumab in Participants With Programmed Death-Ligand 1 (PD-L1) Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) [FIR] | completed | Phase 2 | 138 | Genentech, Inc.INDUSTRY | 5 | Jan 8, 2019 | clinicaltrials |
Data updated 24 days agoSource updated unknownsource: clinicaltrials