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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
398 stopped studies mapped to Sarcoma and descendants · 90% state a reason
Over the 398 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT02633254 | Targeted Vessel Ablation of Type 3 Uterine Fibroids With Magnetic Resonance Guided High… | N/A | terminated | Dec 17, 2015 | UMC Utrecht | not stated | Not stated |
| NCT01504308 | Sonalleve Fibroid Ablation Pivotal Clinical Trial for MR-HIFU of Uterine Fibroids(SOFIA) | Phase 2 / Phase 3 | terminated | Jan 5, 2012 | Philips Healthcare | It was not possible to enroll patients into the study in a realistic timeframe. | Enrollment / accrual |
| NCT00582608 | Tumor Detection Using Iodine-131-Labeled Monoclonal Antibody 8H9 | N/A | terminated | Dec 28, 2007 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT00881595 | Proton Chemoradiotherapy for High-Risk Soft Tissue Sarcomas(SA02) | Phase 2 | withdrawn | Apr 15, 2009 | University of Florida | No patients accrued since study opened | Enrollment / accrual |
| NCT00901836 | Preoperative Proton Radiotherapy for Retroperitoneal Sarcoma(SA03) | N/A | terminated | May 14, 2009 | University of Florida | Study closed due to feasability | Other (stated, no rule matched) |
| NCT01971060 | a Study to Evaluate Adhesion Risk in Fertility Patients' Status Post Laparoscopic…(VLocmyo) | N/A | withdrawn | Oct 28, 2013 | The Advanced Gynecologic Surgery Institute | lack of funding | Funding |
| NCT01194284 | Surveillance Study of Patients With Newly Diagnosed Osteosarcoma | — | terminated | Sep 2, 2010 | Millennium Pharmaceuticals, Inc. | Regulatory agency commitment fulfilled. | Other (stated, no rule matched) |
| NCT00550654 | Conformal Radiation Therapy in Treating Patients With Metastatic Cancer Outside the Brain | Phase 2 | terminated | Oct 30, 2007 | National Institutes of Health Clinical Center (CC) | Study was terminated due to poor accrual. | Enrollment / accrual |
| NCT01204450 | Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma,… | Phase 1 | terminated | Sep 17, 2010 | UNC Lineberger Comprehensive Cancer Center | Funding has become unavailable | Funding |
| NCT01061606 | Temsirolimus in Treating Patients With Recurrent or Persistent Cancer of the Uterus | Phase 2 | terminated | Feb 3, 2010 | National Cancer Institute (NCI) | Poor accrual | Enrollment / accrual |
| NCT02367651 | Study of Pazopanib Versus Placebo as Maintenance Therapy for Advanced Soft Tissue Sarcoma | Phase 2 | withdrawn | Feb 20, 2015 | GlaxoSmithKline | Study cancelled: Withdrawn before enrollment of any participants | Enrollment / accrual |
| NCT01555073 | Preemptive Analgesia Following Uterine Artery Embolization | Phase 4 | terminated | Mar 15, 2012 | Northwestern University | Subjects did not meet inclusion criteria | Other (stated, no rule matched) |
| NCT02080416 | Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumors | Early Phase 1 | terminated | Mar 6, 2014 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Very slow accrual; terminated to allow resources to be utilized more effectively on other studies.… | Enrollment / accrual |
| NCT02464332 | Safety Study of BLZ-100 in Adult Subjects With Sarcoma Undergoing Surgery | Phase 1 | withdrawn | Jun 8, 2015 | Blaze Bioscience Inc. | Study did not enroll any subjects | Enrollment / accrual |
| NCT01675011 | Embozene Microspheres for Uterine Fibroid Embolization (UFE) | N/A | terminated | Aug 29, 2012 | Boston Scientific Corporation | Inadequate enrollment | Enrollment / accrual |
| NCT00123786 | Study of 18F-Fluorodeoxyglucose (FluGlucoScan) in Patients With Known or Suspected Soft… | Phase 2 | terminated | Jul 26, 2005 | AHS Cancer Control Alberta | Lack of Enrollment | Enrollment / accrual |
| NCT02059850 | NY-ESO-1 Specific T Cells After Cyclophosphamide in Treating Patients With Advanced… | Phase 1 | withdrawn | Feb 11, 2014 | Fred Hutchinson Cancer Center | not stated | Not stated |
| NCT01734863 | Post-operative Radiotherapy in Poor Responders Ewing's Sarcoma Patients | Phase 3 | withdrawn | Nov 28, 2012 | Children's Cancer Hospital Egypt 57357 | not stated | Not stated |
| NCT00003273 | Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With… | Phase 2 | withdrawn | Jan 27, 2003 | NYU Langone Health | not stated | Not stated |
| NCT01842594 | A Phase II Trial of Combined Hydroxychloroquine and Sirolimus in Soft Tissue Sarcoma | Phase 2 | terminated | Apr 29, 2013 | Shin Kong Wu Ho-Su Memorial Hospital | Most patients completed only the primary objective (PET) and not went throught the secondary… | Efficacy / futility |
| NCT01104298 | Doxorubicin vs. Trabectedin Plus Doxorubicin in Non Operable and/or Metastatic STS | Phase 2 | terminated | Apr 15, 2010 | Grupo Espanol de Investigacion en Sarcomas | Interim analysis did not show good results for main objective | Efficacy / futility |
| NCT00093678 | Celecoxib in Managing Pain, Weight Loss, and Weakness in Patients With Advanced Cancer | N/A | withdrawn | Oct 8, 2004 | Eastern Cooperative Oncology Group | not stated | Not stated |
| NCT00996346 | Phase I/II Study of Irinotecan and Temsirolimus in Patients With Refractory Sarcomas | Phase 1 | terminated | Oct 16, 2009 | New Mexico Cancer Research Alliance | Original PI left institution and sponsor decided to end support. | Investigator |
| NCT00322855 | Chart Review of Treatments Received by Patients Diagnosed With Soft Tissue Sarcoma | — | terminated | May 8, 2006 | New Mexico Cancer Research Alliance | Low accrual | Enrollment / accrual |
| NCT02137564 | Gamma Secretase Inhibitor PF-03084014 in Treating Patients With AIDS-Associated Kaposi… | Phase 2 | withdrawn | May 14, 2014 | AIDS Malignancy Consortium | Drug supply unavailable | Drug supply |
| NCT02507076 | Isolated Limb Perfusion With Melphalan in Treating Patients With Stage IIIB-IV Melanoma… | N/A | withdrawn | Jul 23, 2015 | Albert Einstein College of Medicine | no enrollment | Enrollment / accrual |
| NCT01174537 | New Castle Disease Virus (NDV) in Glioblastoma Multiforme (GBM), Sarcoma and Neuroblastoma | Phase 1 / Phase 2 | withdrawn | Aug 3, 2010 | Hadassah Medical Organization | not stated | Not stated |
| NCT00019864 | Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma | Phase 2 | terminated | Jan 27, 2003 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT02022358 | Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side… | Phase 2 | terminated | Dec 27, 2013 | University College, London | Recruitment almost complete, has been slow and challenging | Enrollment / accrual |
| NCT01010958 | Adjuvant Valproate for High Grade Sarcomas | Phase 1 | terminated | Nov 10, 2009 | Columbia University | Slow accrual | Enrollment / accrual |
| NCT00755261 | Phase II Study of Doxorubicin and Avastin® in Sarcoma. | Phase 2 | terminated | Sep 18, 2008 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | The study has been terminated due to low accrual. | Enrollment / accrual |
| NCT00427414 | Liposomal Daunorubicin in Treating Patients With HIV-Related Kaposi's Sarcoma | Phase 1 | terminated | Jan 29, 2007 | AIDS Malignancy Consortium | Terminated due to slow accrual. | Enrollment / accrual |
| NCT00022542 | BMS-247550 in Treating Patients With Advanced Soft Tissue Sarcoma | Phase 2 | terminated | Feb 27, 2004 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00969917 | Study Evaluating the Efficacy and Safety of IPI 504 in Patients With Advanced… | Phase 2 | withdrawn | Sep 2, 2009 | Infinity Pharmaceuticals, Inc. | Company decision not to start the study | Sponsor / business decision |
| NCT01226290 | Fibroid Ablation Study(FAST-EU) | N/A | terminated | Oct 22, 2010 | Gynesonics | Investigational device changes; adequate enrollment achieved | Enrollment / accrual |
| NCT00233948 | Nelfinavir Mesylate in Treating Patients With Recurrent, Metastatic, or Unresectable… | Phase 1 / Phase 2 | terminated | Oct 6, 2005 | City of Hope Medical Center | Drug availability issues | Drug supply |
| NCT01539187 | Fibroid Ablation Study - Large Fibroids(FAST-L) | N/A | terminated | Feb 27, 2012 | Gynesonics | Investigational device changes | Other (stated, no rule matched) |
| NCT01998854 | Observational Prospective Study on Patients With Symptomatic Uterine Fibroids Treated… | — | terminated | Dec 2, 2013 | Gynesonics | Investigational device changes | Other (stated, no rule matched) |
| NCT01921998 | Development of a Biomarker Directed Strategy to Ameliorate Common Toxicities From…(BioACT) | — | suspended | Aug 14, 2013 | The Christie NHS Foundation Trust | Trial has been suspended due to lack of resource and staff | Other (stated, no rule matched) |
| NCT01795430 | Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed… | N/A | withdrawn | Feb 20, 2013 | City of Hope Medical Center | No participants enrolled. | Enrollment / accrual |
| NCT00624962 | Early Enteral Tube Feedings in Children Receiving Chemo for AML/MDS & High Risk Solid… | N/A | withdrawn | Feb 28, 2008 | Vanderbilt University | no participants enrolled | Enrollment / accrual |
| NCT00615329 | Huntsman Biopsy Study | — | terminated | Feb 14, 2008 | State University of New York - Upstate Medical University | Huntmans Cancer Institute terminated study | Other (stated, no rule matched) |
| NCT00072280 | Surgery and/or Chemotherapy in Treating Children With Infantile, Congenital, or Childhood… | Phase 2 | terminated | Nov 6, 2003 | Children's Oncology Group | Due to poor accrual | Enrollment / accrual |
| NCT00634322 | High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in Osteosarcoma | Phase 2 | terminated | Mar 13, 2008 | BTG International Inc. | Lack of enrollment | Enrollment / accrual |
| NCT00673179 | Doxorubicin With Cisplatin, High-Dose Methotrexate, and Additional Risk-Adapted… | N/A | terminated | May 7, 2008 | M.D. Anderson Cancer Center | Low accrual. | Enrollment / accrual |
| NCT01786226 | Mifepristone to Treat Uterine Fibroids | Phase 2 / Phase 3 | terminated | Feb 7, 2013 | Mediterranea Medica S. L. | not stated | Not stated |
| NCT00544778 | Combination Chemotherapy and Dexrazoxane Followed by Surgery and Radiation Therapy in… | Phase 2 | terminated | Oct 16, 2007 | City of Hope Medical Center | The study was terminated prematurely due to withdrawal of support by the sponsor. | Other (stated, no rule matched) |
| NCT00958893 | An Extension Study Evaluating Safety and Efficacy of Proellex® In Women Who Have… | Phase 2 | terminated | Aug 13, 2009 | Repros Therapeutics Inc. | Repros stopped the study for safety and FDA put the study on hold for safety. | Safety / toxicity |
| NCT00683917 | Pharmacokinetics, Safety and Efficacy Study of Proellex in Pre-menopausal Women With… | Phase 2 | terminated | May 26, 2008 | Repros Therapeutics Inc. | Repros stopped the study for safety and FDA put the study on hold for safety. | Safety / toxicity |
| NCT00702702 | Safety and Efficacy of Proellex in Pre-menopausal Anemic Women With Symptomatic Uterine… | Phase 3 | terminated | Jun 20, 2008 | Repros Therapeutics Inc. | Repros stopped study for safety and FDA put study on hold because of safety. | Safety / toxicity |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Apr 7, 2017source: clinicaltrials