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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
87 stopped studies mapped to Neuroblastoma and descendants · 90% state a reason
Over the 87 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computed
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00960063 | A Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment… | Phase 1 | terminated | Aug 17, 2009 | Merck Sharp & Dohme LLC | Study was terminated for business reasons. | Sponsor / business decision |
| NCT02337309 | SF1126 for Patients With Relapsed or Refractory Neuroblastoma | Phase 1 | terminated | Jan 13, 2015 | New Approaches to Neuroblastoma Therapy Consortium | Low patient accrual | Enrollment / accrual |
| NCT02011126 | Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid Tumors | Phase 2 | withdrawn | Dec 13, 2013 | Children's Oncology Group | IND no longer available. | Other (stated, no rule matched) |
| NCT00602446 | Deferasirox in Treating Patients With Iron Overload After Undergoing a Donor Stem Cell… | Phase 2 | terminated | Jan 28, 2008 | Masonic Cancer Center, University of Minnesota | Due to slow accrual of patients | Enrollment / accrual |
| NCT02164097 | ODSH + ICE Chemotherapy in Pediatric Solid Tumors | Phase 1 | terminated | Jun 16, 2014 | New York Medical College | low accrual | Enrollment / accrual |
| NCT00003926 | Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors | Phase 1 | terminated | May 2, 2003 | Masonic Cancer Center, University of Minnesota | Withdrawn due to slow accrual | Enrollment / accrual |
| NCT00944580 | A Vaccine Study for High Risk Cancers | Phase 1 | withdrawn | Jul 23, 2009 | Penn State University | unexpectedly low screening results leading to poor accrual | Enrollment / accrual |
| NCT00003513 | Antineoplaston Therapy in Treating Patients With Metastatic, Recurrent, or Refractory… | Phase 2 | terminated | Jan 27, 2003 | Burzynski Research Institute | slow accrual | Enrollment / accrual |
| NCT02745756 | A Combined Cell Therapy Approach to the Treatment of Neuroblastoma | Phase 1 | withdrawn | Apr 20, 2016 | H. Lee Moffitt Cancer Center and Research Institute | no enrollment | Enrollment / accrual |
| NCT03013387 | Dosimetry Guided PRRT With 90Y-DOTATOC | Phase 2 | withdrawn | Jan 6, 2017 | Sue O'Dorisio | This project has undergone a significant amount of updates and has been resubmitted under IRB#… | Other (stated, no rule matched) |
| NCT01130623 | A Phase I Study of Pazopanib as a Single Agent for Children With Refractory Solid Tumors | Phase 1 | withdrawn | May 26, 2010 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT02439788 | 3RD GENERATION GD2 SPECIFIC CHIMERIC ANTIGEN RECEPTOR TRANSDUCED AUTOLOGOUS NATURAL…(GINAKIT) | Phase 1 | withdrawn | May 12, 2015 | Baylor College of Medicine | Based on newly available preclinical data we changed the CAR construct to a more effective version… | Other (stated, no rule matched) |
| NCT00808899 | Neuroblastoma Protocol 2008: Therapy for Children With Advanced Stage High Risk… | Phase 2 | terminated | Dec 16, 2008 | St. Jude Children's Research Hospital | Voluntarily closed and terminated by the PI due to lack of feasibility | Other (stated, no rule matched) |
| NCT00324324 | Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem… | Phase 3 | terminated | May 11, 2006 | OHSU Knight Cancer Institute | not stated | Not stated |
| NCT00900068 | Blood Samples From Patients on a Clinical Trial to CINV During HSCT | — | terminated | May 12, 2009 | OHSU Knight Cancer Institute | not stated | Not stated |
| NCT00947167 | A Phase II Study of Pertuzumab and Erlotinib for Metastatic or Unresectable… | Phase 2 | terminated | Jul 27, 2009 | Pamela L. Kunz | Extreme toxicity of Pertuzumab and Erlotinib combination | Safety / toxicity |
| NCT00582608 | Tumor Detection Using Iodine-131-Labeled Monoclonal Antibody 8H9 | N/A | terminated | Dec 28, 2007 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT00946283 | Lactobacillus in Preventing Infection in Patients Undergoing a Donor Stem Cell Transplant… | N/A | terminated | Jul 24, 2009 | Rutgers, The State University of New Jersey | slow accrual | Enrollment / accrual |
| NCT01204450 | Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma,… | Phase 1 | terminated | Sep 17, 2010 | UNC Lineberger Comprehensive Cancer Center | Funding has become unavailable | Funding |
| NCT00670410 | Autologous Transplant Followed by Allogeneic Transplant for High Risk Neuroblastoma | Phase 1 | terminated | May 1, 2008 | Columbia University | Poor accrual | Enrollment / accrual |
| NCT01048086 | 90Y DOTA/Retinoic Acid for Neuroblastoma and Neuroendocrine Tumor (NET) | Phase 2 | withdrawn | Jan 13, 2010 | University of Iowa | No patients were enrolled because the company that pledged the drug does not yet have it available. | Enrollment / accrual |
| NCT01440283 | A Phase II Study of Intensity Modulated Radiation Therapy (IMRT) in High Risk Abdominal… | Phase 2 | terminated | Sep 26, 2011 | St. Jude Children's Research Hospital | not stated | Not stated |
| NCT00003273 | Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With… | Phase 2 | withdrawn | Jan 27, 2003 | NYU Langone Health | not stated | Not stated |
| NCT00992173 | Efficacy and Safety of Ultratrace™ Iobenguane I 131 in Neuroblastoma | Phase 2 | withdrawn | Oct 9, 2009 | Molecular Insight Pharmaceuticals, Inc. | not stated | Not stated |
| NCT00874315 | Allogeneic Hematopoietic Stem Cell Transplantation for Relapsed or Refractory High-Risk… | Phase 2 | withdrawn | Apr 2, 2009 | Nationwide Children's Hospital | lack of accrual | Enrollment / accrual |
| NCT01174537 | New Castle Disease Virus (NDV) in Glioblastoma Multiforme (GBM), Sarcoma and Neuroblastoma | Phase 1 / Phase 2 | withdrawn | Aug 3, 2010 | Hadassah Medical Organization | not stated | Not stated |
| NCT00624962 | Early Enteral Tube Feedings in Children Receiving Chemo for AML/MDS & High Risk Solid… | N/A | withdrawn | Feb 28, 2008 | Vanderbilt University | no participants enrolled | Enrollment / accrual |
| NCT01077440 | Presence of Donor-Derived DNA in Semen Samples From Cancer Survivors Who Underwent Donor… | — | terminated | Mar 1, 2010 | Vanderbilt University | PI leaving institution | Other (stated, no rule matched) |
| NCT01404702 | Pilot Study of Zoledronic Acid and Interleukin-2 for Refractory Pediatric Neuroblastoma | Phase 1 | terminated | Jul 28, 2011 | University of Alabama at Birmingham | Accrual slower than anticipated | Enrollment / accrual |
| NCT01319838 | Aflac ST1001 Prolonged Isotretinoin(Aflac ST1001) | Phase 1 | withdrawn | Mar 22, 2011 | Emory University | no patient enrollment | Enrollment / accrual |
| NCT00389766 | High-Dose Iodine I 131 Metaiodobenzylguanidine, Topotecan, and Peripheral Stem Cell… | Phase 2 | withdrawn | Oct 19, 2006 | Children's Cancer and Leukaemia Group | Withdrawn because protocol has been discontinued. It was never opened. | Other (stated, no rule matched) |
| NCT00053950 | Pyrazoloacridine and Stem Cell or Bone Marrow Transplantation in Treating Young Patients… | Phase 1 | terminated | Feb 6, 2003 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00054405 | Interleukin-12 and Interleukin-2 in Treating Patients With Refractory or Recurrent… | Phase 1 | terminated | Feb 6, 2003 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00969722 | A Study of MAb-3F8 Plus Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Versus… | Phase 2 | terminated | Sep 1, 2009 | United Therapeutics | Lack of enrollment. | Enrollment / accrual |
| NCT01558778 | Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem… | N/A | withdrawn | Mar 20, 2012 | Roswell Park Cancer Institute | device not available | Other (stated, no rule matched) |
| NCT00533169 | ZD6474 Alone and in Combination With Retinoic Acid in Pediatric Neuroblastoma | Phase 1 | terminated | Sep 21, 2007 | M.D. Anderson Cancer Center | Lack of enrollment. | Enrollment / accrual |
| NCT00813501 | Immunologic Diagnostic Blood Test in Predicting Side-Effects in Patients Undergoing a… | — | terminated | Dec 23, 2008 | City of Hope Medical Center | Terminated at the request of the study sponsor | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Aug 27, 2018source: clinicaltrials