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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
1,672 stopped studies mapped to Malignant Reproductive System Neoplasm and descendants · 89% state a reason
Over the 1,672 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01613521 | Tumor Perfusion and Hypoxia Assessed by DCE-MRI and 18F-FMISO PET as Biomarkers of… | N/A | terminated | Jun 7, 2012 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT01100866 | Study of POMELLA™ Extract to Treat Prostate Cancer | N/A | terminated | Apr 9, 2010 | Vancouver Coastal Health | due to slow enrollment | Enrollment / accrual |
| NCT01007214 | Guided Biopsy for Mapping Prostate Cancer(HIT) | N/A | terminated | Nov 3, 2009 | Roswell Park Cancer Institute | Not able to meet accrual | Enrollment / accrual |
| NCT00887640 | Impact of Temsirolimus Therapy on Circulating Tumor Cell Biology In Men With Castration… | Phase 2 | terminated | Apr 24, 2009 | Duke University | not stated | Not stated |
| NCT01734681 | Phase 2 Study of G-202 in Patients With Chemotherapy-Naïve Metastatic Castrate-Resistant… | Phase 2 | withdrawn | Nov 28, 2012 | GenSpera, Inc. | not stated | Not stated |
| NCT00967928 | Everolimus Dose Finding Study for Stage IV or Recurrent Cervical Cancer | Phase 1 | withdrawn | Aug 28, 2009 | Accelerated Community Oncology Research Network | Lack of enrollment | Enrollment / accrual |
| NCT01176513 | GE-148-002: A Phase 2, Open-label, Single-Center Study to Assess GE-148 (18F) Injection… | Phase 2 | terminated | Aug 6, 2010 | GE Healthcare | Lack of Subject enrollment | Enrollment / accrual |
| NCT01409473 | Stereotactic Body Radiotherapy (SBRT) With Concurrent Boost for Low- and…(Prostate SBRT) | Phase 2 | withdrawn | Aug 4, 2011 | Rocky Mountain Cancer Centers | not stated | Not stated |
| NCT00479635 | A Phase II Trial of TPI 287 in Patients With Metastatic Prostate Cancer | Phase 2 | terminated | May 28, 2007 | Cortice Biosciences, Inc. | Sponsor could no longer support; enrollment stopped August 2008. | Enrollment / accrual |
| NCT01403103 | Cholecalciferol(25-[OH]-Vitamin D) in Treating Patients With Colorectal Cancer | Early Phase 1 | withdrawn | Jul 27, 2011 | Case Comprehensive Cancer Center | Slow Accrual | Enrollment / accrual |
| NCT00922129 | Effectiveness of Conversion to Sirolimus Versus Calcineurin Inhibitor (CNI) Reduction in… | Phase 2 / Phase 3 | withdrawn | Jun 17, 2009 | St. Joseph's Healthcare Hamilton | Study did not start up as planned. | Other (stated, no rule matched) |
| NCT01000948 | A Safety Study of ZD4054 in Prior Chemotherapy Treated Patients With Metastatic…(DAPROCA-1) | Phase 2 | terminated | Oct 23, 2009 | Aarhus University Hospital | A consequence of the results of the ENTHUSE phase III study program | Other (stated, no rule matched) |
| NCT01202890 | Study of Revlimid With Doxil and Avastin for Patients With Platinum Resistant Ovarian… | Phase 1 | terminated | Sep 16, 2010 | New Mexico Cancer Research Alliance | Terminated due to inadequate rate of accrual. | Enrollment / accrual |
| NCT00917865 | FACBC Positron Emission Tomography/Computed Tomography(PET/CT) Used in the Diagnosis of… | Phase 2 | terminated | Jun 10, 2009 | David M. Schuster, MD | Optimal histolgic verification support such as whole mount analysis could not be made available. | Other (stated, no rule matched) |
| NCT01131039 | Safety and Efficacy Study of Gemcitabine Plus Bevacizumab in Patients With… | Phase 2 | withdrawn | May 26, 2010 | Emory University | PI left Emory | Investigator |
| NCT01982487 | Vaccine Therapy and IDO1 Inhibitor INCB024360 in Treating Patients With Epithelial… | Phase 1 / Phase 2 | withdrawn | Nov 13, 2013 | Roswell Park Cancer Institute | not stated | Not stated |
| NCT00510224 | Sandostatin for Patients With Androgen Independent Prostate Cancer | Phase 2 | terminated | Aug 1, 2007 | University of California, San Francisco | Stopped at interim analyses phase due to lack of efficacy | Efficacy / futility |
| NCT00768742 | Safety and Effectiveness Study of RF Ablation of Uterine Fibroids to Reduce Menstrual…(FAST) | N/A | withdrawn | Oct 8, 2008 | Gynesonics | study revised and reinitiated under another protocol | Other (stated, no rule matched) |
| NCT00681148 | Botulinum Toxin Injection With Prostate Brachytherapy | Phase 2 | withdrawn | May 21, 2008 | Emory University | No funding | Funding |
| NCT00138151 | Isotretinoin, Interferon Alpha-2b, and Paclitaxel in Stage IV, Recurrent, or Persistent… | Phase 2 | terminated | Aug 30, 2005 | University of Medicine and Dentistry of New Jersey | Slow accrual and lack of study drug | Enrollment / accrual |
| NCT00945477 | Pazopanib as Second Line Therapy in Patients With Metastatic Prostate Cancer Refractory… | Phase 2 | terminated | Jul 24, 2009 | Illinois CancerCare, P.C. | Slow enrollment | Enrollment / accrual |
| NCT00831233 | Symptomatic Study Investigating Degarelix in Patients Suffering From Prostate Cancer | Phase 3 | terminated | Jan 28, 2009 | Ferring Pharmaceuticals | Poor recruitment due to rare targeted population | Enrollment / accrual |
| NCT00053833 | S0025 Irinotecan in Treating Patients With Refractory Ovarian Epithelial, Primary… | Phase 2 | terminated | Feb 6, 2003 | SWOG Cancer Research Network | lack of accrual | Enrollment / accrual |
| NCT00072540 | S0212 Celecoxib in Treating Patients With High-Grade Squamous Intraepithelial Lesions of… | Phase 2 | withdrawn | Nov 5, 2003 | SWOG Cancer Research Network | drug issues | Other (stated, no rule matched) |
| NCT01617174 | Observational Longitudinal Study of Pain in Men With Metastatic Castrate-Resistant… | — | withdrawn | Jun 12, 2012 | Memorial Sloan Kettering Cancer Center | not stated | Not stated |
| NCT00005075 | Ultrasound in Treating Patients With Recurrent Stage I or Stage II Prostate Cancer | Phase 3 | terminated | Feb 25, 2004 | EDAP Technomed | Withdrawn because Ablatherm devices were not available anymore at trial centers | Other (stated, no rule matched) |
| NCT01743547 | The Effects Of Yoga On Quality Of Life Among A Population Of Ovarian/ Fallopian Tube/… | N/A | terminated | Dec 6, 2012 | Northwestern University | The investigators concluded that it is not feasible due to the lack of participation and difficulty… | Enrollment / accrual |
| NCT00814892 | Vaccine Therapy in Treating Patients With Non-Metastatic Prostate Cancer | Phase 2 | terminated | Dec 25, 2008 | Mayo Clinic | Study was terminated due to funding issues. | Funding |
| NCT00907634 | Prospective Evaluation of Intrafractional and Interfractional Cervical Motion During… | — | withdrawn | May 22, 2009 | Emory University | Study closed by IRB because a Continuing Review and/or Close-Out have not been submitted. Study… | Other (stated, no rule matched) |
| NCT01481233 | Oral Colchicine in Men With Castrate Resistant Prostate Cancer | Phase 2 | withdrawn | Nov 29, 2011 | Milton S. Hershey Medical Center | Due to funding | Funding |
| NCT00085631 | Cisplatin and Radiation Therapy With or Without Hyperthermia Therapy in Treating Patients… | Phase 3 | terminated | Jun 11, 2004 | Mark Dewhirst | Study was closed because of slow accrual | Enrollment / accrual |
| NCT00382330 | Chemoprevention of Cancer in the Lower Female Genital Tract: The Antineoplastic Activity… | N/A | withdrawn | Sep 29, 2006 | University of Medicine and Dentistry of New Jersey | not stated | Not stated |
| NCT00085527 | FR901228 in Treating Patients With Relapsed or Refractory Advanced Ovarian Epithelial… | Phase 2 | withdrawn | Jun 11, 2004 | University of Chicago | not stated | Not stated |
| NCT01321697 | A Non-Randomized Study to Evaluate Leg Lymphatic Drainage Associated With Surgical… | — | terminated | Mar 23, 2011 | University of Arkansas | Principal Investigator Request | Investigator |
| NCT01197209 | Neoadjuvant Study of In-situ REIC/Dkk-3 in Prostate Cancer | Phase 1 | withdrawn | Sep 9, 2010 | Momotaro-Gene Inc. | Suspended due to change in development plans and investigator | Investigator |
| NCT00084370 | Celecoxib in Preventing Cancer in Patients at High Risk for Ovarian Epithelial Cancer Who… | N/A | withdrawn | Jun 11, 2004 | University of Alabama at Birmingham | not stated | Not stated |
| NCT00685633 | Bicalutamide With or Without Enzastaurin in Treating Patients With Prostate Cancer | Phase 2 | withdrawn | May 28, 2008 | Eastern Cooperative Oncology Group | not stated | Not stated |
| NCT01010334 | Comparison of Standard of Care or Treatment on Protocol | N/A | terminated | Nov 10, 2009 | New Mexico Cancer Research Alliance | PI deparature and very low (\<2%) accrual rate.(No results required) | Enrollment / accrual |
| NCT00017537 | Vaccine Therapy in Treating Patients With Metastatic or Recurrent Cancer | Phase 1 | withdrawn | Jan 8, 2004 | University of Alabama at Birmingham | not stated | Not stated |
| NCT00080639 | CA-125 in Screening Patients at High Risk for Ovarian Cancer | — | withdrawn | Apr 8, 2004 | University of Alabama at Birmingham | Terminated for administrative reasons and becuase there were no enrollments | Enrollment / accrual |
| NCT01821859 | Abraxane/Bevacizumab | Phase 2 | terminated | Apr 1, 2013 | OHSU Knight Cancer Institute | Terminated due to low enrollment | Enrollment / accrual |
| NCT00796874 | Magnetic Resonance Imaging in Detecting Cancer Progression in Patients With Early Stage… | N/A | withdrawn | Nov 24, 2008 | Roswell Park Cancer Institute | PI decided to terminate study. | Other (stated, no rule matched) |
| NCT00942838 | Whole Abdomen Radiation in Conjunction With Intraperitoneal Chemotherapy for the…(WAR) | Phase 1 | withdrawn | Jul 21, 2009 | University of Utah | PI decision due to under accrual. | Enrollment / accrual |
| NCT01899391 | Periperal Blood Lymphocytes During Prostate RT | — | withdrawn | Jul 15, 2013 | University Health Network, Toronto | Recuritment Challenges | Other (stated, no rule matched) |
| NCT01498237 | Photoacoustic Endoscopy in Endometrial Cancer | Early Phase 1 | withdrawn | Dec 23, 2011 | Washington University School of Medicine | Need to obtain IDE prior to commencement of study | Other (stated, no rule matched) |
| NCT00003517 | Antineoplaston Therapy in Treating Patients With Stage III or Stage IV Prostate Cancer | Phase 2 | withdrawn | Jan 27, 2003 | Burzynski Research Institute | not stated | Not stated |
| NCT00084565 | Paclitaxel, Topotecan, and Estramustine in Treating Patients With Metastatic… | Phase 2 | withdrawn | Jun 11, 2004 | Fox Chase Cancer Center | Study was never activated at Fox Chase Cancer Center. | Other (stated, no rule matched) |
| NCT00566644 | Intrauterine Levonorgestrel and Observation or Observation Alone in Preventing Atypical… | Phase 3 | terminated | Dec 3, 2007 | St George's, University of London | Withdrawn due to poor accrual | Enrollment / accrual |
| NCT00748527 | Carboplatin With or Without Decitabine in Treating Patients With Progressive, Advanced… | Phase 2 | terminated | Sep 8, 2008 | Cancer Research UK | The study was "withdrawn" due to certain adverse events \[hypersensitivity\]. | Safety / toxicity |
| NCT00003378 | Combination Chemotherapy in Treating Patients With Previously Untreated Stage III or… | Phase 1 | terminated | Aug 26, 2004 | Gynecologic Oncology Group | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Mar 13, 2014source: clinicaltrials