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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
1,672 stopped studies mapped to Malignant Reproductive System Neoplasm and descendants · 89% state a reason
Over the 1,672 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00096304 | Epirubicin and Docetaxel in Treating Patients With Metastatic Prostate Cancer | Phase 1 | terminated | Nov 9, 2004 | Medical University of South Carolina | Low accrual | Enrollment / accrual |
| NCT01773889 | A Trial of Intravenous Denileukin Diftitox Plus Subcutaneous Pegylated IFNα-2A in Stage… | Phase 2 | terminated | Jan 23, 2013 | The University of Texas Health Science Center at San Antonio | Lack of funding | Funding |
| NCT02708511 | Copper Cu 64-DOTA-B-Fab PET/CT in Imaging Patients With Ovarian and Breast Cancer | Phase 1 | terminated | Mar 15, 2016 | Sanjiv Sam Gambhir | not stated | Not stated |
| NCT02765698 | Efficacy of PET/MRI in Detecting Metastatic Disease in Endometrial Cancer | — | terminated | May 9, 2016 | Mayo Clinic | not stated | Not stated |
| NCT00860158 | Neoadjuvant Dasatinib Plus LHRH Analogue Therapy in High-Risk Localized Prostate Cancer | Phase 2 | terminated | Mar 12, 2009 | Noah Hahn, M.D. | Slow accrual; closed by funder | Enrollment / accrual |
| NCT02110277 | Photoacoustic Imaging of the Ovary | N/A | terminated | Apr 10, 2014 | UConn Health | Dr Zhu, collaborator and the inventor of the photoacoustic system, is leaving the institution and… | Other (stated, no rule matched) |
| NCT01188408 | Efficacy and Safety Study of LE-DT to Treat Metastatic Castrate Resistant Prostate Cancer | Phase 2 | withdrawn | Aug 25, 2010 | INSYS Therapeutics Inc | Study shut-down in 12/2010 when NeoPharm merged with Insys. | Other (stated, no rule matched) |
| NCT00408070 | Bevacizumab Study With Carboplatin & Paclitaxel in Ovarian, Fallopian Tube or Primary… | Phase 2 | terminated | Dec 6, 2006 | UConn Health | Did not meet accrual goals. | Enrollment / accrual |
| NCT01859338 | Soft Tissue Detection on MRI, Cone Beam CT and Fan Beam CT and Integration of Functional… | — | terminated | May 21, 2013 | Virginia Commonwealth University | Slow accrual | Enrollment / accrual |
| NCT02349139 | Safety, Preliminary Efficacy and Pharmacokinetics of ASN001 in Metastatic Castrate… | Phase 1 | terminated | Jan 28, 2015 | Asana BioSciences | Business Decision | Sponsor / business decision |
| NCT02110953 | Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal… | Phase 1 | terminated | Apr 10, 2014 | Fox Chase Cancer Center | IRB study closure by investigator due to low enrollment | Investigator |
| NCT00004261 | EF5 Prior to Surgery or Biopsy in Patients With Breast, Prostate, or Cervical Cancer or… | Phase 1 | terminated | Dec 11, 2003 | University Health Network, Toronto | Lack of patient accrual | Enrollment / accrual |
| NCT01936974 | (PGA) for Platinum-resistant/Refractory, Paclitaxel-Pretreated Recurrent Ovarian and…(PGA) | Phase 2 | terminated | Sep 6, 2013 | Western Regional Medical Center | PI Decision | Other (stated, no rule matched) |
| NCT00588263 | Anonymous Testing of Pathology Specimens for BRCA Mutations in Ashkenazi Jewish… | — | withdrawn | Jan 8, 2008 | Memorial Sloan Kettering Cancer Center | Data from MSK-IMPACT is sufficient for relevant analyses going forward | Other (stated, no rule matched) |
| NCT00638378 | Study of Ruxolitinib (INCB018424) Administered Orally to Patients With Androgen… | Phase 2 | terminated | Mar 19, 2008 | Incyte Corporation | According to the protocol, the sponsor terminated the study after it was determined that less than… | Other (stated, no rule matched) |
| NCT02546427 | Hypofractionated Whole Pelvic Radiotherapy of the Prostate | N/A | withdrawn | Sep 10, 2015 | Albert J. Chang | PI left UCSF and the study was closed without any accruals. | Investigator |
| NCT01934179 | Telomere Length in Predicting Toxicity in Older Patients With Stage III-IV Colorectal… | — | terminated | Sep 4, 2013 | Fox Chase Cancer Center | Low Accrual Rate | Enrollment / accrual |
| NCT02736435 | Treatment of Uterine Fibroids With Magnetic Resonance Guided High Intensity Focused… | Phase 3 | withdrawn | Apr 13, 2016 | Thunder Bay Regional Health Research Institute | Lengthy delays and inadequate support to proceed. | Other (stated, no rule matched) |
| NCT00003516 | Antineoplaston Therapy in Treating Patients With Stage III or Stage IV Prostate Cancer | Phase 2 | terminated | Jan 27, 2003 | Burzynski Research Institute | Slow accrual | Enrollment / accrual |
| NCT00003534 | Antineoplaston Therapy in Treating Patients With Refractory Stage IV Prostate Cancer | Phase 2 | withdrawn | Jan 27, 2003 | Burzynski Research Institute | No participants enrolled. | Enrollment / accrual |
| NCT00303888 | Docetaxel With or Without Phenoxodiol in Treating Patients With Recurrent Advanced… | Phase 1 | terminated | Mar 17, 2006 | Yale University | not stated | Not stated |
| NCT00574951 | AMG 706 in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer,… | Phase 2 | terminated | Dec 17, 2007 | Gynecologic Oncology Group | Study was stopped for severe toxicity causing concern for patients | Safety / toxicity |
| NCT00375804 | Racial Disparity in Endometrial Cancer | — | terminated | Sep 13, 2006 | University of Louisville | Funding and logistical difficuties resulted in the withdrawl of the study. | Funding |
| NCT00585052 | A Phase II Study of Interaction of Lovastatin and Paclitaxel For Patients With Refractory… | Phase 2 | terminated | Jan 2, 2008 | University of Iowa | Slow accrual, PI left the institution | Investigator |
| NCT00720096 | Genomic Directed Salvage Chemotherapy With Either Liposomal Doxorubicin Or Topotecan | N/A | terminated | Jul 22, 2008 | H. Lee Moffitt Cancer Center and Research Institute | Funds for this project have been spent, and it is thereby terminated. | Funding |
| NCT00331422 | Carboplatin, Paclitaxel, and Surgery in Treating Patients With Advanced Ovarian… | Phase 2 | terminated | May 31, 2006 | Masonic Cancer Center, University of Minnesota | Study was terminated due to lack of available funding. | Funding |
| NCT00602446 | Deferasirox in Treating Patients With Iron Overload After Undergoing a Donor Stem Cell… | Phase 2 | terminated | Jan 28, 2008 | Masonic Cancer Center, University of Minnesota | Due to slow accrual of patients | Enrollment / accrual |
| NCT00652899 | Allogeneic Natural Killer Cells in Patients With Recurrent Ovarian Cancer, Fallopian… | Phase 2 | terminated | Apr 4, 2008 | Masonic Cancer Center, University of Minnesota | Withdrawn due to toxicity | Safety / toxicity |
| NCT00903630 | Lenalidomide and Doxorubicin Hydrochloride Liposome in Recurrent Ovarian Epithelial… | Phase 1 / Phase 2 | terminated | May 18, 2009 | Masonic Cancer Center, University of Minnesota | lack of funding | Funding |
| NCT00447616 | Prostatectomy Prospective Database | — | terminated | Mar 15, 2007 | Kenneth Peters, MD | Lack of funding | Funding |
| NCT00918645 | Calcium-41 (41Ca) Chloride Aqueous Solution in Diagnosing Patients With Prostate Cancer…(UCDCC#217) | N/A | terminated | Jun 11, 2009 | University of California, Davis | not stated | Not stated |
| NCT02131207 | MRI Before Biopsy in Diagnosing Patients With Prostate Cancer | — | terminated | May 6, 2014 | Case Comprehensive Cancer Center | Principal Investigator Left Institution | Investigator |
| NCT00769990 | Genistein in Treating Patients Undergoing External-Beam Radiation Therapy for Bone… | Phase 1 / Phase 2 | withdrawn | Oct 9, 2008 | Masonic Cancer Center, University of Minnesota | No patient accrual. | Enrollment / accrual |
| NCT00003532 | Antineoplaston Therapy in Treating Patients With Stage III or Stage IV Ovarian Cancer | Phase 2 | terminated | Jan 27, 2003 | Burzynski Research Institute | Slow accrual | Enrollment / accrual |
| NCT00003533 | Antineoplaston Therapy in Treating Patients With Metastatic Prostate Cancer | Phase 2 | terminated | Jan 27, 2003 | Burzynski Research Institute | Slow accrual | Enrollment / accrual |
| NCT01575444 | Cervical Cancer Screening Project Part C | — | terminated | Apr 11, 2012 | University of Minnesota | Investigator left University No results are possible | Investigator |
| NCT00348816 | Docetaxel, Radiation Therapy, and Prednisone in Treating Patients Who Have Undergone… | Phase 2 | terminated | Jul 6, 2006 | The University of Texas Health Science Center at San Antonio | Loss of funding | Funding |
| NCT01200810 | Bicalutamide and RO4929097 in Treating Patients With Previously Treated Prostate Cancer | Phase 2 | terminated | Sep 14, 2010 | National Cancer Institute (NCI) | Drug was no longer available | Other (stated, no rule matched) |
| NCT01260909 | Real-Time MV/kV Image Guided Radiation Therapy | — | withdrawn | Dec 15, 2010 | Stanford University | Business decision | Sponsor / business decision |
| NCT01281254 | AMG 386 (Trebananib) in Ovarian Cancer (TRINOVA-2) | Phase 3 | terminated | Jan 21, 2011 | Amgen | Closure of long term follow up (LTFU) and study earlier than previously outlined in the protocol as… | Other (stated, no rule matched) |
| NCT00003926 | Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors | Phase 1 | terminated | May 2, 2003 | Masonic Cancer Center, University of Minnesota | Withdrawn due to slow accrual | Enrollment / accrual |
| NCT00287859 | Topotecan in Treating Patients With Ovarian Epithelial, Fallopian Tube, or Primary… | Phase 1 | terminated | Feb 7, 2006 | Masonic Cancer Center, University of Minnesota | Withdrawn due to low accrual | Enrollment / accrual |
| NCT00428194 | Erlotinib, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB-Stage IVA… | Phase 1 | withdrawn | Jan 29, 2007 | Masonic Cancer Center, University of Minnesota | Withdrawn due to lack of accrual | Enrollment / accrual |
| NCT00278434 | Zoledronate in Treating Patients With Cervical Intraepithelial Neoplasia 2/3 or 3 | Phase 1 | terminated | Jan 18, 2006 | University of California, San Francisco | Accrual was insufficient to meet study endpoints | Enrollment / accrual |
| NCT00524589 | Calcitriol and Dexamethasone in Treating Patients With Prostate Cancer That Did Not… | Phase 2 | terminated | Sep 3, 2007 | Roswell Park Cancer Institute | closed due to futility | Efficacy / futility |
| NCT00562185 | Doxorubicin and Carboplatin in Treating Patients With Recurrent Ovarian Cancer | Phase 1 / Phase 2 | withdrawn | Nov 21, 2007 | University of Texas Southwestern Medical Center | Funding source withdrew funding | Funding |
| NCT00070317 | Lymph Node Mapping and Sentinel Lymph Node Identification in Patients With Stage IB1… | N/A | terminated | Oct 7, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT02793219 | Provenge Followed by Docetaxel in Castration-Resistant Prostate Cancer | Phase 2 | withdrawn | Jun 8, 2016 | The University of Texas Health Science Center, Houston | Dendreon was sold and new company decided not to fund study. | Funding |
| NCT02793765 | Docetaxel Followed by Provenge in Metastatic Prostate Cancer | Phase 2 | withdrawn | Jun 8, 2016 | The University of Texas Health Science Center, Houston | Dendreon was sold and new company decided not to fund study. | Funding |
| NCT01748890 | A Pilot Trial of Sonoelastography for Planning Tumor-targeted Prostate Biopsy | N/A | terminated | Dec 13, 2012 | Massachusetts General Hospital | Insufficient recruitment | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 24 days agoSource updated Apr 10, 2018source: clinicaltrials