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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
476 stopped studies mapped to Malignant Ovarian Neoplasm and descendants · 86% state a reason
Over the 476 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01202890 | Study of Revlimid With Doxil and Avastin for Patients With Platinum Resistant Ovarian… | Phase 1 | terminated | Sep 16, 2010 | New Mexico Cancer Research Alliance | Terminated due to inadequate rate of accrual. | Enrollment / accrual |
| NCT01131039 | Safety and Efficacy Study of Gemcitabine Plus Bevacizumab in Patients With… | Phase 2 | withdrawn | May 26, 2010 | Emory University | PI left Emory | Investigator |
| NCT01982487 | Vaccine Therapy and IDO1 Inhibitor INCB024360 in Treating Patients With Epithelial… | Phase 1 / Phase 2 | withdrawn | Nov 13, 2013 | Roswell Park Cancer Institute | not stated | Not stated |
| NCT00053833 | S0025 Irinotecan in Treating Patients With Refractory Ovarian Epithelial, Primary… | Phase 2 | terminated | Feb 6, 2003 | SWOG Cancer Research Network | lack of accrual | Enrollment / accrual |
| NCT01743547 | The Effects Of Yoga On Quality Of Life Among A Population Of Ovarian/ Fallopian Tube/… | N/A | terminated | Dec 6, 2012 | Northwestern University | The investigators concluded that it is not feasible due to the lack of participation and difficulty… | Enrollment / accrual |
| NCT00085527 | FR901228 in Treating Patients With Relapsed or Refractory Advanced Ovarian Epithelial… | Phase 2 | withdrawn | Jun 11, 2004 | University of Chicago | not stated | Not stated |
| NCT00084370 | Celecoxib in Preventing Cancer in Patients at High Risk for Ovarian Epithelial Cancer Who… | N/A | withdrawn | Jun 11, 2004 | University of Alabama at Birmingham | not stated | Not stated |
| NCT01010334 | Comparison of Standard of Care or Treatment on Protocol | N/A | terminated | Nov 10, 2009 | New Mexico Cancer Research Alliance | PI deparature and very low (\<2%) accrual rate.(No results required) | Enrollment / accrual |
| NCT00017537 | Vaccine Therapy in Treating Patients With Metastatic or Recurrent Cancer | Phase 1 | withdrawn | Jan 8, 2004 | University of Alabama at Birmingham | not stated | Not stated |
| NCT00080639 | CA-125 in Screening Patients at High Risk for Ovarian Cancer | — | withdrawn | Apr 8, 2004 | University of Alabama at Birmingham | Terminated for administrative reasons and becuase there were no enrollments | Enrollment / accrual |
| NCT01821859 | Abraxane/Bevacizumab | Phase 2 | terminated | Apr 1, 2013 | OHSU Knight Cancer Institute | Terminated due to low enrollment | Enrollment / accrual |
| NCT00942838 | Whole Abdomen Radiation in Conjunction With Intraperitoneal Chemotherapy for the…(WAR) | Phase 1 | withdrawn | Jul 21, 2009 | University of Utah | PI decision due to under accrual. | Enrollment / accrual |
| NCT00748527 | Carboplatin With or Without Decitabine in Treating Patients With Progressive, Advanced… | Phase 2 | terminated | Sep 8, 2008 | Cancer Research UK | The study was "withdrawn" due to certain adverse events \[hypersensitivity\]. | Safety / toxicity |
| NCT00003378 | Combination Chemotherapy in Treating Patients With Previously Untreated Stage III or… | Phase 1 | terminated | Aug 26, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00006267 | Nitrocamptothecin in Treating Patients With Recurrent or Metastatic Ovarian Epithelial or… | Phase 2 | withdrawn | Jan 27, 2003 | Gynecologic Oncology Group | Never activated. | Other (stated, no rule matched) |
| NCT00084448 | Paclitaxel and Celecoxib in Treating Patients With Recurrent or Persistent… | Phase 2 | terminated | Jun 11, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00002478 | Etoposide in Treating Patients With Advanced Ovarian or Cervical Cancer | Phase 2 | terminated | Jun 9, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003380 | Liposomal Doxorubicin and Etoposide in Treating Patients With Recurrent or Persistent… | Phase 1 | terminated | Aug 16, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003382 | Combination Chemotherapy Consisting of Gemcitabine And Topotecan in Treating Patients… | Phase 1 | terminated | Jul 15, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003794 | Quality-of-Life Study of Patients With Previously Treated Ovarian Cancer | — | terminated | Oct 29, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00017134 | Fenretinide Followed by Surgery Compared With Surgery Alone in Preventing Ovarian Cancer… | N/A | terminated | May 7, 2003 | Gynecologic Oncology Group | Withdrawn due to poor accrual | Enrollment / accrual |
| NCT00369954 | Gemcitabine and Carboplatin in Treating Patients With Persistent or Recurrent Ovarian… | Phase 2 | withdrawn | Aug 30, 2006 | Gynecologic Oncology Group | Trial was never activated | Other (stated, no rule matched) |
| NCT00477867 | Economic Outcomes in Patients With Stage III Ovarian Cancer Receiving Paclitaxel and… | N/A | withdrawn | May 24, 2007 | Gynecologic Oncology Group | Trial was never activated | Other (stated, no rule matched) |
| NCT00583622 | Bevacizumab Plus Gemcitabine, Docetaxel, Melphalan, and Carboplatin in Ovarian Cancer… | Phase 2 | terminated | Dec 31, 2007 | M.D. Anderson Cancer Center | Slow Accrual | Enrollment / accrual |
| NCT01383408 | Distinction Between Lung Cancer and Gynecological Cancers by Canine Scent Detection | Phase 2 | terminated | Jun 28, 2011 | Schillerhoehe Hospital | Inconsistent training status of sniffer dogs | Other (stated, no rule matched) |
| NCT00002819 | Chemotherapy With or Without Peripheral Stem Cell Transplantation in Treating Patients… | Phase 3 | terminated | May 26, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003386 | Vaccine Therapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer | Phase 2 | terminated | Apr 23, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003624 | Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine,… | Phase 2 | terminated | Jun 16, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00004037 | Docetaxel in Treating Patients With Recurrent or Refractory Ovarian or Primary Peritoneal… | Phase 2 | terminated | Jun 25, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00006812 | Capecitabine in Treating Patients With Recurrent Ovarian Epithelial or Primary Peritoneal… | Phase 2 | terminated | Mar 17, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00023907 | Paclitaxel in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal… | Phase 2 | terminated | Jul 9, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00091195 | Depsipeptide (Romidepsin) in Treating Patients With Recurrent Ovarian Epithelial or… | Phase 2 | terminated | Sep 9, 2004 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT01016054 | A Study of the Safety and Pharmacokinetics of AGS-8M4 Given in Combination With… | Phase 1 | terminated | Nov 18, 2009 | Astellas Pharma Inc | Trial was terminated to allow sponsors to evaluate the future development of the drug program | Other (stated, no rule matched) |
| NCT00523809 | Allogeneic Hematopoietic Stem Cell Transplantation With Bevacizumab for Advanced Solid… | Phase 2 | terminated | Sep 3, 2007 | M.D. Anderson Cancer Center | Slow accrual. | Enrollment / accrual |
| NCT00042952 | Imatinib Mesylate in Treating Patients With Progressive, Refractory, or Recurrent Stage… | Phase 2 | terminated | Jan 27, 2003 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00087191 | EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or… | N/A | terminated | Jul 12, 2004 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00173407 | PTEN and IGFBP-3 Correlation in Ovarian Carcinoma Invasion | N/A | withdrawn | Sep 15, 2005 | National Taiwan University Hospital | not stated | Not stated |
| NCT00840450 | Imatinib Mesylate (Gleevec) and Paclitaxel in Recurrent Patients of Ovarian and Other… | Phase 2 | terminated | Feb 10, 2009 | NYU Langone Health | Due to slow accrual | Enrollment / accrual |
| NCT01177501 | Trial of High Dose Topotecan With Carboplatin in Patients With Relapsed Ovarian Carcinoma(ITOV04) | Phase 1 | terminated | Aug 9, 2010 | Assistance Publique - Hôpitaux de Paris | choice of the principal investigator | Investigator |
| NCT00288275 | Correlation of the Chemoresponse Assay With PFS in Patients With Recurrent Epithelial… | — | terminated | Feb 7, 2006 | Precision Therapeutics | not stated | Not stated |
| NCT00669422 | ChemoFx® PRO - A Post-Market Data Collection Study | — | terminated | Apr 30, 2008 | Precision Therapeutics | not stated | Not stated |
| NCT00460200 | Depression and Interleukin-6 Production in Patients With Ovarian Epithelial Cancer | — | withdrawn | Apr 13, 2007 | Jonsson Comprehensive Cancer Center | no patient accrual | Enrollment / accrual |
| NCT00005612 | Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating…(ETC) | Phase 1 / Phase 2 | terminated | May 3, 2004 | H. Lee Moffitt Cancer Center and Research Institute | Low accrual | Enrollment / accrual |
| NCT00006356 | Chemotherapy With or Without Surgery in Treating Patients With Recurrent Ovarian Cancer | Phase 3 | terminated | Jan 27, 2003 | European Organisation for Research and Treatment of Cancer - EORTC | low accrual | Enrollment / accrual |
| NCT00516841 | A Phase 2, Single-Arm Study of Volociximab Monotherapy in Subjects With… | Phase 2 | terminated | Aug 16, 2007 | Facet Biotech | Decision to terminate recruitment based on lack of efficacy | Efficacy / futility |
| NCT01661868 | Olaparib for Patients With Recurrent BRCA Deficient Ovarian Cancer | Phase 2 | withdrawn | Aug 10, 2012 | Dana-Farber Cancer Institute | Drug not available. | Other (stated, no rule matched) |
| NCT00085384 | PEG-Interferon Alfa-2b in Treating Patients With Platinum-Resistant Ovarian Epithelial,… | Phase 1 / Phase 2 | terminated | Jun 11, 2004 | M.D. Anderson Cancer Center | Terminated due to slow accrual. | Enrollment / accrual |
| NCT00897806 | Identifying Genetic Markers That Predict Response to Paclitaxel in Patients With Newly… | — | terminated | May 12, 2009 | M.D. Anderson Cancer Center | Terminated due to slow accrual. | Enrollment / accrual |
| NCT01558778 | Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem… | N/A | withdrawn | Mar 20, 2012 | Roswell Park Cancer Institute | device not available | Other (stated, no rule matched) |
| NCT00006262 | Rebeccamycin Analogue in Treating Patients With Refractory Stage III or Stage IV Ovarian… | Phase 2 | terminated | Mar 25, 2004 | Northwestern University | Unable to accrue patients to the study. | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Jan 8, 2014source: clinicaltrials