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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
76 stopped studies mapped to Malignant Oropharyngeal Neoplasm and descendants · 89% state a reason
Over the 76 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API ().
reasonMatches| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01267240 | Capecitabine and Vorinostat in Treating Patients With Recurrent and/or Metastatic Head… | Phase 2 | terminated | Dec 28, 2010 | National Cancer Institute (NCI) | Study treatment did not show clinical activity. | Other (stated, no rule matched) |
| NCT00797446 | Photon/Proton Radiation Therapy for Oropharyngeal Cancers(OP01) | — | terminated | Nov 25, 2008 | University of Florida | Slow enrollment, feasibility issues | Enrollment / accrual |
| NCT01283178 | Phase I Study of IMRT and Molecular-Image Guided Adaptive Radiation Therapy for Advanced… | Phase 1 | terminated | Jan 25, 2011 | Virginia Commonwealth University | The study was terminated. The data analysis was futile with only 3 accruals. PI opted to terminate… | Enrollment / accrual |
| NCT01528137 | Talactoferrin in Treating Patients With Relapsed or Refractory Non-Small Cell Lung Cancer… | Phase 1 | terminated | Feb 7, 2012 | Stanford University | Negative data from another trial led to termination of this trial by sponsor. | Other (stated, no rule matched) |
| NCT02334319 | Ganetespib Window of Opportunity Study in Head and Neck Cancers | Phase 1 | terminated | Jan 8, 2015 | Emory University | Lack of funding | Funding |
| NCT00537199 | OraTest in Combination With Visual Examination and Visual Examination Alone | Phase 3 | terminated | Sep 28, 2007 | M.D. Anderson Cancer Center | Study terminated early as per request by sponsor, Zila Biotechnology, Inc. | Other (stated, no rule matched) |
| NCT02119728 | Photodynamic Therapy With HPPH in Treating Patients With Squamous Cell Carcinoma of the… | Phase 2 | withdrawn | Apr 22, 2014 | Roswell Park Cancer Institute | not stated | Not stated |
| NCT01586182 | Stereotactic Boost for Oropharyngeal Squamous Cell Carcinoma | Phase 1 / Phase 2 | withdrawn | Apr 26, 2012 | Dana-Farber Cancer Institute | Local IRB closed the study due to poor accural. | Other (stated, no rule matched) |
| NCT01949740 | Patient Preferences in Making Treatment Decisions in Patients With Stage I-IVA… | — | terminated | Sep 24, 2013 | University of Chicago | Poor accrual | Enrollment / accrual |
| NCT02156180 | Identification of Breath Biomarkers in Head and Neck Squamous Cell Carcinoma | — | suspended | Jun 5, 2014 | Queensland Centre of Excellence for Head and Neck Cancer | Awaiting funding to facilitate selected-ion flow-tube mass spectrometry (SIFT/MS) | Funding |
| NCT01953952 | Radiation Therapy and Cisplatin With or Without Surgery in Treating Patients With Stage… | Phase 2 | withdrawn | Oct 1, 2013 | Radiation Therapy Oncology Group | Slow accrual | Enrollment / accrual |
| NCT01254734 | Transoral Robotic Surgery in Treating Patients With Benign or Stage I-IV Head and Neck… | N/A | terminated | Dec 7, 2010 | City of Hope Medical Center | The study will be rewritten as a data registry study | Other (stated, no rule matched) |
| NCT01718223 | Photodynamic Therapy Using Temoporfin Before Surgery in Treating Patients With Recurrent… | N/A | withdrawn | Oct 31, 2012 | Roswell Park Cancer Institute | implementation issues | Other (stated, no rule matched) |
| NCT01682031 | Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck… | Phase 2 | terminated | Sep 10, 2012 | Roswell Park Cancer Institute | Due to a lack of funding | Funding |
| NCT01175499 | Concordance of Two Endoscopic Procedures for Diagnosis of Carcinoma of the Upper…(TNFE-NBI) | N/A | withdrawn | Aug 4, 2010 | University of California, San Francisco | Unable to obtain funding to continue recruitment; no accrual | Enrollment / accrual |
| NCT01728480 | Entolimod in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer… | Phase 1 | withdrawn | Nov 19, 2012 | Roswell Park Cancer Institute | Financial Sponsor requested termination | Funding |
| NCT00095641 | S0225 Capecitabine in Treating Patients Who Have Undergone Surgery for Locally Recurrent… | Phase 2 | withdrawn | Nov 8, 2004 | SWOG Cancer Research Network | no longer studying this disease site | Other (stated, no rule matched) |
| NCT00006106 | ONYX-015 With Cisplatin and Fluorouracil in Treating Patients With Advanced Head and Neck… | Phase 1 | withdrawn | Apr 29, 2004 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00906360 | Sunitinib, Cetuximab, and Radiation Therapy in Treating Patients With Locally Advanced or… | Phase 1 | terminated | May 21, 2009 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01674374 | Botanical Therapy in Treating Mucositis in Patients With Head and Neck Cancer Who Have… | Phase 2 | withdrawn | Aug 28, 2012 | Roswell Park Cancer Institute | not stated | Not stated |
| NCT00033449 | Gefitinib and Radiation Therapy With or Without Cisplatin in Treating Patients With Stage… | Phase 1 | terminated | Jan 27, 2003 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT00081211 | Intratumoral PV701 in Treating Patients With Advanced or Recurrent Unresectable Squamous… | Phase 1 | terminated | Apr 8, 2004 | National Cancer Institute (NCI) | Administratively complete. | Other (stated, no rule matched) |
| NCT01066741 | Prevention of Radiation-induced Severe Oral Mucositis in Oral Cavity, Oropharynx,… | Phase 3 | terminated | Feb 10, 2010 | Centre Leon Berard | insufficient recruitment, the planed sample size appears not achievable | Enrollment / accrual |
| NCT00928161 | Reflux Disease in Head and Neck Cancer Patients Undergoing Radiation Therapy | N/A | withdrawn | Jun 25, 2009 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT00951470 | Complete Decongestive Therapy (CDT) for Treatment of Head and Neck Lymphedema | N/A | withdrawn | Aug 4, 2009 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT00080028 | Motexafin Gadolinium With Chemotherapy and Radiation Therapy for the Treatment of… | Phase 1 | terminated | Mar 23, 2004 | Pharmacyclics LLC. | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Apr 14, 2017source: clinicaltrials