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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
876 stopped studies mapped to Malignant Male Reproductive System Neoplasm and descendants · 91% state a reason
Over the 876 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT04403568 | Testing the Synergism of Phytonutrients, Curcumin and Ursolic Acid, to Target Molecular… | Early Phase 1 | withdrawn | May 27, 2020 | The University of Texas Health Science Center at San Antonio | No subjects were enrolled in this study, the PI will seek funding and revise the protocol for… | Enrollment / accrual |
| NCT01805037 | Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+… | Phase 1 / Phase 2 | terminated | Mar 5, 2013 | Northwestern University | Lack of funding | Funding |
| NCT03545165 | 177Lu-J591 and 177Lu-PSMA-617 Combination for mCRPC | Phase 1 / Phase 2 | terminated | Jun 4, 2018 | Weill Medical College of Cornell University | Sponsor withdrawal | Other (stated, no rule matched) |
| NCT04296578 | Study Evaluating Sodium Selenite in Combination With Abiraterone in Castrate Resistant… | Phase 1 | withdrawn | Mar 5, 2020 | Stanford University | Study did not start | Other (stated, no rule matched) |
| NCT02985021 | Docetaxel and Carboplatin for Patients With mCRPC and DNA-Repair Deficiencies | Phase 2 | terminated | Dec 7, 2016 | Seattle Institute for Biomedical and Clinical Research | Competing studies | Other (stated, no rule matched) |
| NCT03829930 | Combination of Entinostat and Enzalutamide in Advanced Prostate Cancer | Phase 1 | terminated | Feb 4, 2019 | George Washington University | Sponsor discontinued the drug | Other (stated, no rule matched) |
| NCT02108613 | Living Well on Androgen Deprivation Therapy | N/A | withdrawn | Apr 9, 2014 | British Columbia Cancer Agency | It was deemed not enough funding and the initial funding returned and study withdrawn (never opened… | Enrollment / accrual |
| NCT00911079 | Pilot Study of a Catheter-based Ultrasound Hyperthermia System | N/A | terminated | Jun 1, 2009 | University of California, San Francisco | Low Accrual | Enrollment / accrual |
| NCT02432820 | Assessment of 3D Transperineal Ultrasound Imaging w/ Matrix Array Transducers in Prostate… | — | terminated | May 4, 2015 | Stanford University | Business decision | Sponsor / business decision |
| NCT04486846 | Electronic Post-Treatment Surveillance Program for Prostate Cancer Survivors (eHealth) | N/A | withdrawn | Jul 27, 2020 | Duke University | Principal Investigator left Duke University | Investigator |
| NCT03927924 | High-intensity Focused Ultrasound Study | N/A | terminated | Apr 25, 2019 | Chinese University of Hong Kong | due to funding | Funding |
| NCT03532308 | Nutrition and Prostate Cancer | Phase 3 | terminated | May 22, 2018 | Yale University | Unable to meet recruitment goals. | Enrollment / accrual |
| NCT01802307 | Focal Therapy for Prostate Cancer | Phase 2 | withdrawn | Mar 1, 2013 | University of Maryland, Baltimore | Study was withdrawn | Other (stated, no rule matched) |
| NCT02805894 | NBTXR3 Nanoparticles and EBRT or EBRT With Brachytherapy in the Treatment of Prostate… | Phase 1 / Phase 2 | terminated | Jun 20, 2016 | Nanobiotix | Prostate cancer treatment has greatly changed since the initiation of this trial and therefore we… | Other (stated, no rule matched) |
| NCT03478904 | Study to Compare Capsule and Liquid Formulations of Enzalutamide After Single Dose… | Phase 1 | terminated | Mar 27, 2018 | National Cancer Institute (NCI) | Study drug is now commercially available in tablet format | Other (stated, no rule matched) |
| NCT01566045 | MRI/TRUS Fusion Guided Prostate Biopsy- An Improved Way to Detect and Quantify Prostate… | N/A | withdrawn | Mar 29, 2012 | Philips Healthcare | not stated | Not stated |
| NCT00621413 | Observation of Outcomes and Side Effects of Cesium-131 in Combination With External Beam… | — | withdrawn | Feb 22, 2008 | IsoRay Medical, Inc. | Study never moved forward due to no accrual | Enrollment / accrual |
| NCT02497638 | LIpitor and biGuanide to Androgen Delay Trial(LIGAND) | Phase 2 | withdrawn | Jul 14, 2015 | University Health Network, Toronto | Drug intervention no longer relevant for the proposed population | Other (stated, no rule matched) |
| NCT02685267 | Docetaxel/Prednisone Versus Docetaxel/Prednisone and Enzalutamide in Castration-Resistant…(Doce/Enza) | Phase 2 | terminated | Feb 18, 2016 | Prostate Cancer Clinical Trials Consortium | not stated | Not stated |
| NCT00991315 | Collecting and Storing Blood and Tumor Tissue Samples From Patients Undergoing… | — | terminated | Oct 8, 2009 | Rutgers, The State University of New Jersey | Specimens are now collected through the BRS protocol. | Other (stated, no rule matched) |
| NCT02853097 | Cell-Free DNA and RNA in Blood fromMetastatic Prostate Cancer Patients | — | terminated | Aug 2, 2016 | University of Southern California | Slow accrual | Enrollment / accrual |
| NCT01376661 | Outcome Assessment of an Active Surveillance Program for Low Risk Prostate Cancer: An… | — | terminated | Jun 20, 2011 | St. Joseph Hospital of Orange | Early termination due to PI's decision to discontinue research activities. | Other (stated, no rule matched) |
| NCT01678443 | Monoclonal Antibody Therapy Before Stem Cell Transplant in Treating Patients With… | Phase 1 | terminated | Sep 5, 2012 | Fred Hutchinson Cancer Center | Terminated due to low accrual. | Enrollment / accrual |
| NCT03589781 | Investigating the Effects of Mikei® Red Reishi Essence EX on the Immune System of… | N/A | withdrawn | Jul 18, 2018 | Nikkei (Canada) Marketing Limited | Covid 19 Pandemic - Unable to enroll patients | COVID-19 / pandemic |
| NCT03042312 | Lutetium-177 (Lu177) Prostate-Specific Antigen (PSMA)-Directed EndoRadiotherapy(RESIST-PC) | Phase 2 | terminated | Feb 3, 2017 | Endocyte | Recruitment was stopped before the target sample size was achieved. | Enrollment / accrual |
| NCT04305379 | Augmented BLAdder NecK rEconstruction Trial for Improved Urinary Function After Radical…(BLANKET) | N/A | terminated | Mar 12, 2020 | Johns Hopkins University | Stopped due to COVID-19 pandemic, low priority among initiatives and officially terminated. | COVID-19 / pandemic |
| NCT02295163 | Stellate Ganglion Block for Hot Flushes in Men Treated With ADT | N/A | withdrawn | Nov 20, 2014 | Rijnstate Hospital | no participants | Other (stated, no rule matched) |
| NCT03572478 | Rucaparib and Nivolumab in Patients With Prostate or Endometrial Cancer | Phase 1 / Phase 2 | terminated | Jun 28, 2018 | University of Chicago | The study was terminated due to lack of efficacy. | Efficacy / futility |
| NCT01717677 | Evaluation of Four Treatment Modalities in Prostate Cancer With Low or "Early…(PREFERE) | N/A | terminated | Oct 30, 2012 | Association of Urologic Oncology (AUO) | Insufficient Recruitment | Enrollment / accrual |
| NCT03261336 | Oral Calcitriol With Ketoconazole in CRPC | Phase 2 | terminated | Aug 25, 2017 | Donald Trump, MD | can not meet enrollment | Enrollment / accrual |
| NCT03741712 | A Study of SHR2554 Alone or in Combination With SHR3680 in the Treatment of mCRPC | Phase 1 / Phase 2 | terminated | Nov 15, 2018 | Jiangsu HengRui Medicine Co., Ltd. | According to the available data from the trial,the sponsor determined to terminate this study. | Other (stated, no rule matched) |
| NCT03514836 | A Phase I/II, Safety Clinical Trial of DCVAC/PCa and ONCOS-102 in Men With Metastatic… | Phase 1 / Phase 2 | terminated | May 2, 2018 | SOTIO a.s. | insufficient accrual | Enrollment / accrual |
| NCT02698176 | A Dose Exploration Study With Birabresib (MK-8628) in Participants With Selected Advanced… | Phase 1 | terminated | Mar 3, 2016 | Merck Sharp & Dohme LLC | This study was terminated due to limited efficacy and not due to safety reasons. | Safety / toxicity |
| NCT02844582 | Cabazitaxel and Prednisone in Treating Patients With Metastatic Hormone-Resistant… | Phase 2 | terminated | Jul 26, 2016 | University of California, Davis | Poor accrual of subjects onto study | Enrollment / accrual |
| NCT04585932 | Androgen Deprivation Therapy and Apalutamide With or Without Radiation Therapy for the… | Phase 2 | withdrawn | Oct 14, 2020 | M.D. Anderson Cancer Center | At the request of the ad interim Department Chairman due to PI is no longer at institution. | Other (stated, no rule matched) |
| NCT03327662 | Utilising CTC Counts to Optimize Systemic Therapy of Metastatic Prostate Cancer(CTC-STOP) | Phase 3 | terminated | Oct 31, 2017 | Institute of Cancer Research, United Kingdom | Underrecruitment | Other (stated, no rule matched) |
| NCT00757757 | A Phase I/II Open-label Study of MCS110 in Patients With Prostate Cancer and Bone… | Phase 1 / Phase 2 | terminated | Sep 23, 2008 | Novartis Pharmaceuticals | not stated | Not stated |
| NCT04027270 | Pelvic Health and Physical Therapy to Improve Lives of Prostate Cancer Patients… | N/A | withdrawn | Jul 19, 2019 | University of Missouri-Columbia | Covid | COVID-19 / pandemic |
| NCT03563352 | Nutritional Preferences and Product Accessibility in Oral Nutritional Supplements in… | — | withdrawn | Jun 20, 2018 | University of Southern California | Zero accrual | Enrollment / accrual |
| NCT00058188 | Zolendronate for the Prevention of Bone Loss in Men w/ Prostate CA on Long-Term Androgen… | Phase 3 | terminated | Apr 9, 2003 | Northwestern University | Closed by the research committee | Other (stated, no rule matched) |
| NCT00780975 | A Study of Aplidin ( Plitidepsin) in Subjects With Advanced Prostate Cancer | Phase 2 | terminated | Oct 28, 2008 | PharmaMar | Poor recruitment | Enrollment / accrual |
| NCT03308734 | Effects of 6 Week Reduced Exertion High Intensity Interval Training Protocol in Patients… | N/A | withdrawn | Oct 13, 2017 | University of Bath | Lack of resource from collaborating organisation | Other (stated, no rule matched) |
| NCT01691976 | Mild Cognitive Impairment in Men Following Androgen Deprivation | N/A | withdrawn | Sep 25, 2012 | Imperial College London | No one recruited due to resource limitations. Issues with how complicated the study could be for… | Enrollment / accrual |
| NCT04225299 | Evaluation of Efficacy of TOOKAD® (VTP) Versus Active Surveillance for Intermediate Risk… | Phase 3 | withdrawn | Jan 13, 2020 | Steba Biotech S.A. | FDA didn't approve the design of the protocol so we didn't start the study | Other (stated, no rule matched) |
| NCT04399824 | Focal Radiation Therapy for the Treatment of Low or Intermediate-Risk Prostate Cancer | N/A | withdrawn | May 22, 2020 | Jonsson Comprehensive Cancer Center | Study did not open | Other (stated, no rule matched) |
| NCT04266262 | High-Intensity Training for Men With Prostate Cancer on Active Surveillance: A… | N/A | terminated | Feb 12, 2020 | University of Toronto | All research activities were suspended as a result of COVID-19. | COVID-19 / pandemic |
| NCT03724253 | [68Ga]-NeoBOMB1 Imaging in Patients With Malignancies Known to Overexpress Gastrin…(NeoFIND) | Phase 2 | terminated | Oct 30, 2018 | Advanced Accelerator Applications | Recruitment was stopped before the target sample size was achieved. | Enrollment / accrual |
| NCT01928485 | Green Tea Extract in Treating Patients With Low-Risk Prostate Cancer | Phase 2 | terminated | Aug 26, 2013 | Sanjay Gupta PhD | Slow Accrual | Enrollment / accrual |
| NCT02006927 | A Pilot Study of the Feasibility of Chronic Cavernous Nerve Stimulation to Promote… | N/A | terminated | Dec 10, 2013 | Kenneth M Peters, MD | Lack of Enrollment | Enrollment / accrual |
| NCT00004026 | CT-2584 in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to… | Phase 2 | terminated | Aug 27, 2004 | CTI BioPharma | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Sep 16, 2021source: clinicaltrials