High-Intensity Training for Men With Prostate Cancer on Active Surveillance: A Feasibility Study

Inclusion Criteria:

* 18 years or older;
* initiating or currently on AS for PCa;
* not currently engaging in high-intensity aerobic and/or resistance training at 85%HRmax or ≥9 RPE in the Borg 0-10 RPE scale;
* willing and able to travel to the study-designated facilities;
* proficient in English;
* able to provide written informed consent;
* pass the screening CPET by achieving volitional exhaustion (rate of perceived exertion (RPE) ≥ 9 using the Borg 0-10 RPE scale) in the absence of any cardiorespiratory abnormalities.

Exclusion Criteria:

* uncontrolled hypertension (≥2/3 of readings of \> 160/90), regardless of whether on a regimen of anti-hypertensive therapy or not;
* been diagnosed with congestive heart failure (New York Heart Association Class II, III or IV);
* a history of serious cardiovascular events (within 12 months) including, but not limited to, transient ischemic attack (TIA), cerebrovascular accident (CVA), or myocardial infarction (MI);
* a medical condition such as uncontrolled infection or cardiac disease that, in the opinion of the study physician, would make this protocol unreasonably hazardous for the patient;
* a history of a psychiatric illness, which would prevent the patient from giving informed consent or adhering to the study protocol;
* serious or non-healing wound, ulcer, or bone fracture;
* experience shortness of breath, chest discomfort, or palpitations when performing activities of daily living;
* ongoing restriction of physical activity;
* developed chest pain in the past month