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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
876 stopped studies mapped to Malignant Male Reproductive System Neoplasm and descendants · 91% state a reason
Over the 876 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT02079155 | Robotic Athermal Nerve-Sparing Radical Prostatectomy | N/A | withdrawn | Mar 5, 2014 | Case Comprehensive Cancer Center | Research Cancelled | Other (stated, no rule matched) |
| NCT00250757 | Prostate Cancer Diagnosis Through NMR Spectroscopy of Semen and Prostatic Secretions | — | terminated | Nov 8, 2005 | New Mexico Cancer Research Alliance | Study was not renewed timely with IRB of record. | Other (stated, no rule matched) |
| NCT00734851 | Multimodality Phase II Study in Prostate Cancer | Phase 2 | terminated | Aug 14, 2008 | Duke University | Dose Limiting Toxicities | Safety / toxicity |
| NCT00932672 | Atkins Diet and Prostate Cancer Clinical Trial | Phase 2 | terminated | Jul 3, 2009 | Duke University | slow recruitment, lack of funding and PI transferred | Enrollment / accrual |
| NCT02139774 | Using Walk With Ease Walking Program With Men 65 and Older Being Treated for Prostate… | — | terminated | May 15, 2014 | UNC Lineberger Comprehensive Cancer Center | inadequate accrual | Enrollment / accrual |
| NCT01279785 | A Pilot Study of 123I-MIP-1072 SPECT/CT Imaging With Optional Compact Gamma Camera Probe… | — | withdrawn | Jan 19, 2011 | Molecular Insight Pharmaceuticals, Inc. | Similar study to be completd once kit for new formulation becomes available. | Other (stated, no rule matched) |
| NCT02396368 | A Study of Radium-223 in Combination With Tasquinimod in Bone-only Metastatic…(Radium-223) | Phase 1 | withdrawn | Mar 24, 2015 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase III study results for the drug Tesquinimod were not promising so it was a drug development… | Other (stated, no rule matched) |
| NCT02024685 | Treatment Decision Analysis Model for Prostate Cancer: A Randomized Trial | N/A | terminated | Dec 31, 2013 | Case Comprehensive Cancer Center | Funding unavailable | Funding |
| NCT02042885 | A Clinical Trial to Determine the Most Suitable Dose of OPB-111001 in Patients With… | Phase 1 / Phase 2 | terminated | Jan 23, 2014 | Otsuka Novel Products GmbH | not stated | Not stated |
| NCT00629330 | Dissemination of Prostate Cancer Screening to PCP's in African American Communities | Phase 4 | terminated | Mar 6, 2008 | Columbia University | Principal Investigator left the institution. | Investigator |
| NCT01530984 | Ipilimumab and GMCSF Immunotherapy for Prostate Cancer | Phase 2 | withdrawn | Feb 10, 2012 | Lawrence Fong | Unable to execute contract | Other (stated, no rule matched) |
| NCT00585416 | Study of CGC-11047 in Patients With Metastatic Hormone Refractory Prostate Cancer | Phase 2 | terminated | Jan 3, 2008 | University of Wisconsin, Madison | Further evaluation of phase I dosing | Other (stated, no rule matched) |
| NCT00288106 | S0437 Long-Term Follow-Up of Patients Who Were Diagnosed With Prostate Cancer on PCPT | — | terminated | Feb 7, 2006 | SWOG Cancer Research Network | Poor accrual resulted in lack of feasibility to evaluate endpoints. | Enrollment / accrual |
| NCT01745718 | Clinical Study Evaluating Targeted Biopsies and Cytological Imprints in Prostate Cancer | N/A | withdrawn | Dec 10, 2012 | Oslo University Hospital | The study was stopped for technical reasons | Other (stated, no rule matched) |
| NCT02185170 | DEPORRA-CoProst: Assessment of New Fluorescence Imagery Techniques Using Prostate Chips… | N/A | terminated | Jul 9, 2014 | University Hospital, Grenoble | Results of 5 first patients show that chips' cauterization interferes the signal | Other (stated, no rule matched) |
| NCT02480010 | A Study of Pertuzumab in Participants With Prostate Cancer | Phase 2 | terminated | Jun 24, 2015 | Hoffmann-La Roche | The study was terminated at the time of interim analysis since none of the participants showed a… | Efficacy / futility |
| NCT00215631 | Can Tadalafil Maintain Erectile Function In Patients Treated With Radiotherapy For… | Phase 3 | terminated | Sep 22, 2005 | Erasmus Medical Center | slow recruitment | Enrollment / accrual |
| NCT01368003 | STA-9090 in Castration-Resistant Prostate Cancer With Assessment of Androgen Receptor… | Phase 2 | withdrawn | Jun 7, 2011 | Toni Choueiri, MD | Loss of funding. | Funding |
| NCT02109224 | Ibrutinib in Treating Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma in Patients With… | Phase 1 | terminated | Apr 9, 2014 | National Cancer Institute (NCI) | Inadequate accrual rate | Enrollment / accrual |
| NCT02022904 | Prostate Cancer Circulating Tumor Cells Based on Epithelial-Mesenchymal Transition Biology | N/A | withdrawn | Dec 30, 2013 | Duke University | not stated | Not stated |
| NCT01561482 | Study of Metformin With Simvastatin for Men With Prostate Carcinoma | Phase 2 | withdrawn | Mar 23, 2012 | Nicholas Mitsiades | Study closed due to slow/low enrollment; no subjects were enrolled. | Enrollment / accrual |
| NCT00809458 | Biomarker Study of Neoadjuvant Vitamin E in Patients With Locally Treatable Prostate… | Phase 3 | terminated | Dec 17, 2008 | New Mexico Cancer Research Alliance | Low rate of accrual. | Enrollment / accrual |
| NCT01808534 | Palifosfamide in Treating Patients With Recurrent Germ Cell Tumors | Phase 2 | terminated | Mar 11, 2013 | Indiana University | Due to Low Accrual | Enrollment / accrual |
| NCT00581113 | Neural Stem Cell Preserving Brain Radiation Therapy & Stereotactic Radiosurgery in… | Phase 3 | terminated | Dec 27, 2007 | Virginia Commonwealth University | New research priorities | Other (stated, no rule matched) |
| NCT01705652 | Study to Assess the Activity of Nexrutine® in Prostate Cancer Patients(Nexrutine) | Phase 2 | terminated | Oct 12, 2012 | The University of Texas Health Science Center at San Antonio | loss of funding | Funding |
| NCT00921258 | Active Control of Prostatic Cancer With Criteria of Latence(SURACAP) | — | terminated | Jun 16, 2009 | Clinique Mutualiste Chirurgicale de la Loire | Financial problem (not enough budget to continue the study) | Funding |
| NCT01242748 | A Degarelix Trial in Patients With Prostate Cancer | Phase 3 | terminated | Nov 17, 2010 | Ferring Pharmaceuticals | Inadequate recruitment resulting in a too low patient number for collection of long term efficacy… | Efficacy / futility |
| NCT01520441 | BOTOX in Men With Prostate Cancer With Lower Urinary Tract Symptoms(LUTS)/Benign… | Early Phase 1 | withdrawn | Jan 30, 2012 | The University of Texas Health Science Center, Houston | not stated | Not stated |
| NCT02424513 | A Study of Positron Emission Tomography (PET) With [89]Zr-Df-IAb2M in Patients With… | Phase 2 | withdrawn | Apr 23, 2015 | ImaginAb, Inc. | Clinical trial was postponed as a result of restructured business priorities. | Sponsor / business decision |
| NCT00118066 | Calcitriol in Preventing Prostate Cancer in Patients With Prostatic Intraepithelial… | Phase 2 | terminated | Jul 11, 2005 | Rutgers, The State University of New Jersey | Slow accruaL, lack of scientific progress | Enrollment / accrual |
| NCT00824928 | Salvage Cryotherapy in Recurrent Prostate Cancer(SCORE) | — | terminated | Jan 19, 2009 | University of Colorado, Denver | Study was ended due to low enrollment | Enrollment / accrual |
| NCT01769911 | Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With… | N/A | withdrawn | Jan 17, 2013 | Fred Hutchinson Cancer Center | not stated | Not stated |
| NCT00176293 | Randomized Phase II Trial of Doxil With or Without Dexamethasone for Metastatic Hormone… | Phase 2 | terminated | Sep 15, 2005 | University of Kentucky | Slow accrual | Enrollment / accrual |
| NCT02420587 | AMG 208 Tumor Microenvironment in Metastatic Castration Resistant Prostate Cancer (mCRPC) | Phase 2 | withdrawn | Apr 20, 2015 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT00217464 | Fulvestrant in Treating Patients With Recurrent Prostate Cancer | Phase 2 | terminated | Sep 22, 2005 | Roswell Park Cancer Institute | Closed for futility | Efficacy / futility |
| NCT01274572 | Blood for Immune Response to Provenge® in HRPC | — | withdrawn | Jan 11, 2011 | Mary Crowley Medical Research Center | Drug became available with insurance reimbursement | Other (stated, no rule matched) |
| NCT01267266 | Saracatinib in Treating Patients With Prostate Cancer | Phase 2 | terminated | Dec 28, 2010 | National Cancer Institute (NCI) | Per protocol, study was terminated due to low rate of randomized patients. | Other (stated, no rule matched) |
| NCT00023634 | S0114 Vaccine Therapy in Treating Patients With Gastric, Prostate, or Ovarian Cancer | Phase 1 | terminated | Jan 27, 2003 | SWOG Cancer Research Network | lack of accrual | Enrollment / accrual |
| NCT00694291 | Sorafenib in Hormone Naïve Biochemical Recurrence of Prostate Cancer | Phase 2 | withdrawn | Jun 10, 2008 | Fox Chase Cancer Center | not stated | Not stated |
| NCT01163448 | Feasibility and Safety Study Using Preoperative High-Dose Single-Fraction Image-Guided… | Phase 1 | withdrawn | Jul 15, 2010 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT01565512 | Dorsal Penile Block for Post-Robotic Prostatectomy Foley Discomfort | Phase 1 / Phase 2 | withdrawn | Mar 28, 2012 | Columbia University | Lack of funding, PI left the institution, poor enrollment | Investigator |
| NCT00058214 | Perifosine in Treating Patients With Recurrent Prostate Cancer | Phase 2 | terminated | Apr 9, 2003 | National Cancer Institute (NCI) | Did not meet interim stopping criteria for continuation to the second stage. | Other (stated, no rule matched) |
| NCT00539968 | A Study to Evaluate the Safety, Tolerability, and Activity of Lonafarnib and Docetaxel… | Phase 1 / Phase 2 | terminated | Oct 5, 2007 | Merck Sharp & Dohme LLC | not stated | Not stated |
| NCT02159690 | A Phase II Neoadjuvant Study of Enzalutamide, Abiraterone Acetate, Dutasteride and… | Phase 2 | withdrawn | Jun 10, 2014 | Kenneth Pienta, MD | loss of funding | Funding |
| NCT02065323 | A Study of Dovitinib With Androgen Deprivation Therapy (ADT) in Patients With Metastatic… | Phase 2 | withdrawn | Feb 19, 2014 | Oscar Goodman, Jr. | Terminated due to budgetary considerations and length of development. | Funding |
| NCT00429338 | 3T Endorectal Magnetic Resonance Spectroscopic Imaging (MRSI) of Prostate | N/A | terminated | Jan 31, 2007 | M.D. Anderson Cancer Center | Slow Accrual | Enrollment / accrual |
| NCT00824902 | Evaluation Ultrasound Elasticity/Tissue Strain-Hardening Imaging for Prostate Cancer… | N/A | terminated | Jan 19, 2009 | M.D. Anderson Cancer Center | Technical Issues | Other (stated, no rule matched) |
| NCT00511576 | Study to Evaluate Combination Treatment of MGCD0103 and Docetaxel (Taxotere®) for… | Phase 1 | terminated | Aug 6, 2007 | Mirati Therapeutics Inc. | Celgene terminated its collaboration agreement with MethylGene for the development of MGCD0103. All… | Other (stated, no rule matched) |
| NCT01950871 | Prostate Guided Biopsy Study Evaluating the Diagnostic Performance of Prostate…(PHSTT-01) | Phase 4 | terminated | Sep 26, 2013 | Advanced Medical Diagnostics s.a. | Sponsor is bankrupt | Other (stated, no rule matched) |
| NCT01838265 | Trial of Prostate Cancer Patients Undergoing Active Surveillance With or Without…(MGM) | — | withdrawn | Apr 24, 2013 | University of Miami | Unlikely to Accrue | Enrollment / accrual |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Jan 22, 2016source: clinicaltrials