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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
876 stopped studies mapped to Malignant Male Reproductive System Neoplasm and descendants · 91% state a reason
Over the 876 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01374087 | Study to Assess the Efficacy of Brachytherapy With or Without Hormone Therapy, Using…(ANABRAQ) | Phase 2 | terminated | Jun 15, 2011 | Ipsen | Slow enrollment of patients. | Enrollment / accrual |
| NCT03408561 | Social Media Listening in Improving Clinical Trial Recruitment in Patients With Cancer | N/A | withdrawn | Jan 24, 2018 | University of Southern California | No accrual | Enrollment / accrual |
| NCT00124917 | Phase I Study of Intensity Modulated Radiation Therapy for Prostate Cancer | Phase 1 | terminated | Jul 28, 2005 | National Cancer Institute (NCI) | Study closed due to unanticipated toxicity/risks to subjects. | Safety / toxicity |
| NCT03011749 | Value of FLT PET/CT in Radium-223 Therapy of mCRPC Patients | N/A | terminated | Jan 5, 2017 | Rigshospitalet, Denmark | not stated | Not stated |
| NCT02710422 | Miami Membrane for Potency (MMEP) Trial(MMEP) | Phase 2 | terminated | Mar 16, 2016 | University of Miami | Lack of Accrual and Inadequate Funding | Enrollment / accrual |
| NCT01126879 | Genistein in Treating Patients With Prostate Cancer | Phase 2 | terminated | May 20, 2010 | Northwestern University | Closed due to low accrual | Enrollment / accrual |
| NCT01737151 | Stereotactic Body Radiation Therapy in Treating Patients With Low- and Intermediate-Risk… | N/A | terminated | Nov 29, 2012 | Virginia Commonwealth University | Slow accrual | Enrollment / accrual |
| NCT01981109 | Positive Imaging Study for Distant Metastases in Patients With Castration-Resistant…(PREDICT) | — | terminated | Nov 11, 2013 | Dendreon | Administrative reasons | Other (stated, no rule matched) |
| NCT00619515 | Stereotactic Radiation Therapy in Treating Patients With Prostate Cancer | N/A | terminated | Feb 21, 2008 | Case Comprehensive Cancer Center | Prematurely terminated at institution request | Other (stated, no rule matched) |
| NCT03514927 | High-Intensity Focused Ultrasound in Treating Participants With Intermediate and… | N/A | withdrawn | May 3, 2018 | University of Southern California | No funding | Funding |
| NCT01727154 | Immune Monitoring Protocol in Men With Prostate Cancer Enrolled in a Clinical Trial of…(PRIME) | — | terminated | Nov 15, 2012 | Dendreon | Administrative reasons | Other (stated, no rule matched) |
| NCT03734575 | ClariCore System Used in Transperineal Prostate Biopsy | N/A | suspended | Nov 8, 2018 | Precision Biopsy, Inc. | Company funding | Funding |
| NCT03157947 | Culturally Tailored Decision Aid for Hispanic Patients Diagnosed With Prostate Cancer | N/A | withdrawn | May 17, 2017 | Case Comprehensive Cancer Center | Study Team did not respond to requests for continuing review approval. | Other (stated, no rule matched) |
| NCT02173522 | Phase II Investigation of Prostate Artery Embolization (PAE) Before Radical Prostatectomy… | N/A | terminated | Jun 25, 2014 | Shivank Bhatia | Recruitment difficulty | Enrollment / accrual |
| NCT02182622 | LDE225 + Docetaxel/Prednisone for Adv/Met Castrate Resistant Prostate Cancer w/ Disease… | Phase 1 | withdrawn | Jul 8, 2014 | Martin Gutierrez | not stated | Not stated |
| NCT01159067 | Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and… | Phase 2 | terminated | Jul 9, 2010 | City of Hope Medical Center | Low enrollment | Enrollment / accrual |
| NCT01408043 | Etoposide, Filgrastim, and Plerixafor in Improving Stem Cell Mobilization in Treating… | N/A | terminated | Aug 3, 2011 | Case Comprehensive Cancer Center | Slow Accrual | Enrollment / accrual |
| NCT00798187 | Efficacy of Cancer Support Programs: A Social Comparison Theory Analysis | — | terminated | Nov 26, 2008 | M.D. Anderson Cancer Center | Terminated at time of CR - 3.26.2019 - JA | Other (stated, no rule matched) |
| NCT01996852 | Improving Erectile Function and Quality of Life After Prostate Cancer Treatment | N/A | terminated | Nov 27, 2013 | Case Comprehensive Cancer Center | Premature terminated at institution request | Other (stated, no rule matched) |
| NCT02121600 | 18F-FCH PET/MRI to Assess Tumor Response in Castration Resistant Prostate Cancer | N/A | terminated | Apr 23, 2014 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Low accrual | Enrollment / accrual |
| NCT02911922 | Randomized Trial of Image -Guided Stereotactic Radiation Therapy (IG-SRT) in Prostate… | N/A | terminated | Sep 22, 2016 | Weill Medical College of Cornell University | Lack of patient accruals. | Enrollment / accrual |
| NCT01811810 | Proton Therapy for High Risk Prostate Cancer | N/A | withdrawn | Mar 15, 2013 | Abramson Cancer Center at Penn Medicine | Unable to recruit | Enrollment / accrual |
| NCT00537849 | Investigational Study For the Treatment of Localized (T1c/T2a) Prostate Cancer With High… | N/A | withdrawn | Oct 1, 2007 | SonaCare Medical | Sponsor withdrew request to conduct study | Other (stated, no rule matched) |
| NCT02501759 | Transrectal MRI-Guided Biopsy in Identifying Cancer in Patients With Suspected Prostate… | N/A | terminated | Jul 17, 2015 | OHSU Knight Cancer Institute | Low enrollment and funding loss. | Enrollment / accrual |
| NCT00996502 | Study of Bevacizumab and Erlotinib for Patients With Hormone Refractory Prostate Cancer | Phase 1 / Phase 2 | terminated | Oct 16, 2009 | Columbia University | Poor enrollment; PI left the institution | Investigator |
| NCT01478828 | Pre-Prostatectomy Lovastatin on Prostate Cancer | N/A | terminated | Nov 23, 2011 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | The study was stopped due to an unanticipated serious adverse event. | Safety / toxicity |
| NCT02742259 | Validation of the Prostate Cancer Assay - Beta+Pivotal(VPCA-B+PIV) | — | withdrawn | Apr 19, 2016 | Celsee Diagnostics | No enrolled participants | Enrollment / accrual |
| NCT01994590 | Dovitinib (TKI258) and Abiraterone Acetate in Metastatic Castrate-Resistant Prostate… | Phase 2 | terminated | Nov 26, 2013 | M.D. Anderson Cancer Center | Sponsor stopped supplying study drug | Other (stated, no rule matched) |
| NCT01445054 | 111 Indium CHX-A DTPA Trastuzumab (Indium-Herceptin) for Imaging Breast Cancer | Early Phase 1 | terminated | Oct 3, 2011 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01163084 | Leuprolide Acetate or Goserelin Acetate With or Without Vismodegib Followed by Surgery in… | Phase 1 / Phase 2 | terminated | Jul 15, 2010 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT02459912 | Unilateral Nerve-Sparing Cryoablation for Low-Risk, Clinically Localized, Unilateral…(POTENT-C) | Phase 2 | terminated | Jun 2, 2015 | NYU Langone Health | Patient recruitment | Enrollment / accrual |
| NCT03227744 | A Pilot Study of Prostate Cancer-specific Anxiety in Active Surveillance | N/A | terminated | Jul 24, 2017 | NYU Langone Health | Study has been terminated | Other (stated, no rule matched) |
| NCT01741753 | BKM120+Abiraterone Acetate for Metastatic CRPC | Phase 1 | terminated | Dec 5, 2012 | Dana-Farber Cancer Institute | Due to slow accrual the supllier of BKM120 asked we cease further enrollment. | Enrollment / accrual |
| NCT01275651 | Biomarkers in Bone Marrow and Blood Samples From Patients With Prostate Cancer Treated… | — | withdrawn | Jan 12, 2011 | Alliance for Clinical Trials in Oncology | Trial closure for NCI NCTN Transition | Other (stated, no rule matched) |
| NCT03147196 | Bicalutamide and Raloxifene Hydrochloride in Treating Patients With Prostate Cancer… | Phase 2 | withdrawn | May 10, 2017 | Mayo Clinic | lack of accrual | Enrollment / accrual |
| NCT02478125 | Pilot Study of Mobilization and Treatment of Disseminated Tumor Cells in Men With… | Phase 1 | terminated | Jun 23, 2015 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Low accrual | Enrollment / accrual |
| NCT01262664 | A First-in-Man, Phase I Evaluation of A Single Cycle of Prohibitin Targeting Peptide 1 in… | Phase 1 | terminated | Dec 17, 2010 | M.D. Anderson Cancer Center | Terminated per PI's request | Other (stated, no rule matched) |
| NCT00544076 | ED Recovery in Men Age </=65 Treated With Bilateral Nerve Sparing Robotic Assisted… | Phase 3 | terminated | Oct 16, 2007 | City of Hope Medical Center | Accrual too slow | Enrollment / accrual |
| NCT00924807 | Safety Study of Sorafenib With Androgen Deprivation and Radiotherapy to Treat Prostate… | Phase 1 / Phase 2 | terminated | Jun 19, 2009 | Beth Israel Medical Center | Sponsor closed the trial | Other (stated, no rule matched) |
| NCT00526591 | Everolimus in Treating Patients With Newly Diagnosed Localized Prostate Cancer | Phase 2 | terminated | Sep 10, 2007 | Jorge A. Garcia, MD | Slow accrual | Enrollment / accrual |
| NCT01703065 | Cabozantinib in Men With Castration-Resistant Prostate Cancer | Phase 2 | terminated | Oct 10, 2012 | University of Washington | Closed 2017 for low accrual. Last data for primary outcome on 02Feb2015. | Enrollment / accrual |
| NCT02494713 | Hormonal Therapy and Chemotherapy Followed by Prostatectomy in Patients With Prostate… | Phase 2 | terminated | Jul 10, 2015 | The University of Texas Health Science Center, Houston | slow enrollment; resource re-allocation | Enrollment / accrual |
| NCT00963300 | MRI in Assessing Hypoxia in Patients With Localized Prostate Cancer Undergoing… | N/A | withdrawn | Aug 21, 2009 | University of Texas Southwestern Medical Center | Project Never Initiated - no human subjects were enrolled and no data regarding humans was… | Enrollment / accrual |
| NCT03296124 | Prognostic Value of Androgen Receptor Expression and Mutations Within Oncogenes and Tumor…(PRX32) | — | withdrawn | Sep 28, 2017 | University of Florida | This project currently does not have any subjects enrolled due to other PI priorities. | Enrollment / accrual |
| NCT00103376 | Bortezomib With or Without Hormone Therapy in Treating Patients With Relapsed Prostate… | Phase 2 | terminated | Feb 8, 2005 | Medical University of South Carolina | Low Accrual | Enrollment / accrual |
| NCT00080782 | Doxorubicin and Strontium-89 With or Without Celecoxib in Treating Patients With… | Phase 2 | terminated | Apr 8, 2004 | M.D. Anderson Cancer Center | Low accrual due to competing trial. | Enrollment / accrual |
| NCT00851682 | Feasibility Study of Prostate Tumor Localization for Focal Cryoablation of Prostate… | N/A | terminated | Feb 26, 2009 | Washington University School of Medicine | Enrollment was stopped and will not resume. Participants are no longer being examined. | Enrollment / accrual |
| NCT02450201 | MRI With C13 Pilot Study Prostate Cancer | Early Phase 1 | terminated | May 21, 2015 | University of California, San Francisco | Low accrual | Enrollment / accrual |
| NCT01354951 | Assessing the Potential for Reduced Toxicity Using Focal Brachytherapy in Early Stage,… | Phase 2 | terminated | May 17, 2011 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT00670046 | Valproic Acid in Treating Patients With Progressive, Non-Metastatic Prostate Cancer | Phase 2 | terminated | May 1, 2008 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | The study was terminated per the PI decision. | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Sep 18, 2019source: clinicaltrials