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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
691 stopped studies mapped to Malignant Head and Neck Neoplasm and descendants · 92% state a reason
Over the 691 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01415986 | Interstitial Photodynamic Therapy (PDT) With Temoporfin for Advanced Head and Neck Cancers | Phase 2 | terminated | Aug 12, 2011 | University of Arkansas | The patient was "lost to follow-up" and the PI left the institution. | Investigator |
| NCT00427102 | MRX, Radiation, and Chemotherapy for Patients With Resected Squamous Cell Carcinoma of… | Phase 1 | terminated | Jan 26, 2007 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | No subjects enrolled and PI went to another facility | Enrollment / accrual |
| NCT01066741 | Prevention of Radiation-induced Severe Oral Mucositis in Oral Cavity, Oropharynx,… | Phase 3 | terminated | Feb 10, 2010 | Centre Leon Berard | insufficient recruitment, the planed sample size appears not achievable | Enrollment / accrual |
| NCT00268372 | S0427, Combination Chemotherapy & RT in Treating Patients With Stage III or Stage IV… | Phase 3 | terminated | Dec 22, 2005 | SWOG Cancer Research Network | SWOG eliminated its head and neck committee | Other (stated, no rule matched) |
| NCT00017277 | Radiation Therapy With or Without Epoetin Alfa in Treating Patients With Head and Neck… | Phase 3 | terminated | Jan 27, 2003 | European Organisation for Research and Treatment of Cancer - EORTC | low accrual | Enrollment / accrual |
| NCT00025298 | Chemotherapy Plus Radiation Therapy With or Without Amifostine in Treating Patients With… | Phase 2 | terminated | Jan 27, 2003 | European Organisation for Research and Treatment of Cancer - EORTC | low accrual | Enrollment / accrual |
| NCT00928161 | Reflux Disease in Head and Neck Cancer Patients Undergoing Radiation Therapy | N/A | withdrawn | Jun 25, 2009 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT00951470 | Complete Decongestive Therapy (CDT) for Treatment of Head and Neck Lymphedema | N/A | withdrawn | Aug 4, 2009 | M.D. Anderson Cancer Center | not stated | Not stated |
| NCT00737360 | Phase II Study of TAS-106 to Treat Head and Neck Cancer | Phase 2 | terminated | Aug 19, 2008 | Taiho Pharmaceutical Co., Ltd. | not stated | Not stated |
| NCT00409331 | Amifostine With IMRT for Submandibular and Sublingual Salivary Sparing During Head and… | Phase 2 | terminated | Dec 8, 2006 | M.D. Anderson Cancer Center | Study terminated by Principal Investigator; no patients completed study. | Investigator |
| NCT00038038 | Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole | N/A | withdrawn | May 27, 2002 | M.D. Anderson Cancer Center | No participants enrolled, study terminated. | Enrollment / accrual |
| NCT00003223 | SWOG-9507, Fenretinide in Treating Patients With Neoplasia of the Mouth | Phase 2 | terminated | Sep 10, 2004 | SWOG Cancer Research Network | Closed due to poor accrual. | Enrollment / accrual |
| NCT00488332 | An Exploratory Study on Optical Assessment of Oral Mucositis | — | terminated | Jun 20, 2007 | M.D. Anderson Cancer Center | Terminated due to slow accrual. | Enrollment / accrual |
| NCT00003040 | S9709, Laser Surgery Plus Radiation Therapy in Treating Patients With Early Stage Cancer… | Phase 2 | terminated | Mar 1, 2004 | SWOG Cancer Research Network | Poor accrual | Enrollment / accrual |
| NCT00017173 | S0011, Gene Therapy & Surgery Followed by Chemo & RT in Newly Diagnosed Cancer of the… | Phase 2 | terminated | Jan 27, 2003 | SWOG Cancer Research Network | Terminated for poor accrual. | Enrollment / accrual |
| NCT00084435 | S0217, Adjuvant Cisplatin and Docetaxel After Complete Resection Stage III or IV Head and…(S0217) | Phase 2 | withdrawn | Jun 11, 2004 | SWOG Cancer Research Network | Poor accrual and suspension of head and neck committee | Enrollment / accrual |
| NCT00466856 | Internal Radiation Therapy in Treating Patients With Liver Metastases From Neuroendocrine… | Phase 2 | terminated | Apr 27, 2007 | Vanderbilt-Ingram Cancer Center | due to slow accrual | Enrollment / accrual |
| NCT00568360 | Endoscopic Capillary Oximetry for Tumor Diagnosis in Head and Neck Cancer | — | terminated | Dec 6, 2007 | Stanford University | Research cancelled; equipment broke | Other (stated, no rule matched) |
| NCT00515957 | Study of LMP1- and LMP2- Specific Cytotoxic T-Lymphocytes (CTL)(DELLA) | Phase 1 | withdrawn | Aug 14, 2007 | Baylor College of Medicine | not stated | Not stated |
| NCT00933114 | Functional Imaging of Tumor and Normal Tissue(FITT) | — | terminated | Jul 7, 2009 | Duke University | Funding ceased | Funding |
| NCT01096381 | Potential Biomarkers for Bevacizumab-Induced High Blood Pressure in Patients With Solid… | — | terminated | Mar 31, 2010 | Vanderbilt-Ingram Cancer Center | funding withdrawn due to fellow's departure from VICC | Funding |
| NCT00585741 | Pilot Study of 18F-FLT PET | N/A | terminated | Jan 3, 2008 | University of Wisconsin, Madison | not stated | Not stated |
| NCT01142414 | Chemotherapy and Radiation Therapy With or Without Panitumumab in Treating Patients Who… | Phase 3 | withdrawn | Jun 11, 2010 | European Organisation for Research and Treatment of Cancer - EORTC | not stated | Not stated |
| NCT00401401 | Zalutumumab in Combination With Chemotherapy and Radiotherapy in Head and Neck Cancer | Phase 1 / Phase 2 | terminated | Nov 20, 2006 | Genmab | MTD was established and patients completed 16 months safety f-up and response assessments. It is… | Safety / toxicity |
| NCT01313390 | Everolimus and Docetaxel in Treating Patients With Recurrent, Locally Advanced, or…(DORA) | Phase 1 / Phase 2 | terminated | Mar 11, 2011 | University College, London | Lack of recruitment | Enrollment / accrual |
| NCT00410865 | Wild Type p53 Adenovirus for Oral Premalignancies | Phase 1 | terminated | Dec 13, 2006 | M.D. Anderson Cancer Center | Sponsor withdrawl prior to study completion. | Other (stated, no rule matched) |
| NCT00937300 | T-cell Based Immunotherapy for Head and Neck Cancer | Phase 1 | withdrawn | Jul 13, 2009 | Inge Marie Svane | The patients eligible for this trial do not exist anymore due to change in procedures. | Other (stated, no rule matched) |
| NCT00169221 | Post-operative Radiotherapy With Cisplatin Alone or in Combination With Iressa in Upper… | Phase 2 | terminated | Sep 15, 2005 | Groupe Oncologie Radiotherapie Tete et Cou | Toxicity in an independent study IMEX. The trial was subsequently terminated (54 pts instead of… | Safety / toxicity |
| NCT00023790 | Photodynamic Therapy in Treating Patients With Skin Cancer or Solid Tumors Metastatic to… | Phase 1 | terminated | Jan 27, 2003 | Case Comprehensive Cancer Center | slow accrual | Enrollment / accrual |
| NCT00805012 | Docetaxel and S-1 in Head and Neck Squamous Cell Carcinoma (HNSCC) | Phase 2 | terminated | Dec 9, 2008 | Seoul National University Hospital | slow accrual rate | Enrollment / accrual |
| NCT01077869 | A Feasibility Study on the Use of F-18-FDG-PET and Optical Imaging in Evaluation of… | — | terminated | Mar 1, 2010 | University Hospital, Ghent | poor recruitment rate | Enrollment / accrual |
| NCT00216138 | Docetaxel and Capecitabine for First Line Treatment of Metastatic Squamous Cell Carcinoma… | Phase 2 | terminated | Sep 22, 2005 | Hoosier Cancer Research Network | Interim analysis results did not meet criteria for second stage of trial | Efficacy / futility |
| NCT00233636 | Iressa and Radiotherapy in the Treatment of the Locally Advanced Inoperable Squamous Cell… | Phase 2 | withdrawn | Oct 6, 2005 | AstraZeneca | not stated | Not stated |
| NCT00927446 | Endoscopy Screening for Esophageal Cancer | — | terminated | Jun 25, 2009 | Lotung Poh-Ai Hospital | not stated | Not stated |
| NCT01124500 | Transdermal Methylphenidate for Cancer-Related Fatigue | N/A | withdrawn | May 17, 2010 | Memorial Sloan Kettering Cancer Center | not stated | Not stated |
| NCT00647140 | Clinical Evaluation of 18F-DOPA Positron Emission Tomography in Medullary Thyroid Cancer(DOPMET) | Phase 2 | terminated | Mar 31, 2008 | Assistance Publique - Hôpitaux de Paris | Insuffisent recruitment | Enrollment / accrual |
| NCT00077103 | Induction Chemotherapy Using Doxorubicin and Cisplatin Followed by Combretastatin A4… | Phase 1 / Phase 2 | terminated | Feb 11, 2004 | Case Comprehensive Cancer Center | slow accrual | Enrollment / accrual |
| NCT00201344 | A Phase III Study of Radiotherapy With or Without Adjuvant C/T in Advanced Stage… | Phase 3 | terminated | Sep 20, 2005 | National Health Research Institutes, Taiwan | not stated | Not stated |
| NCT00540332 | A Study of Palifermin for the Reduction of Oral Mucositis in Subjects With Locally… | Phase 1 / Phase 2 | withdrawn | Oct 8, 2007 | Swedish Orphan Biovitrum | The 20070201 study was terminated based on evaluation of Palifermin solid tumor data. | Other (stated, no rule matched) |
| NCT00195078 | Safety Trial of IRESSA, Cisplatin and Radiation Therapy for Patients With Head and Neck… | Phase 1 / Phase 2 | terminated | Sep 19, 2005 | Weill Medical College of Cornell University | not stated | Not stated |
| NCT00080028 | Motexafin Gadolinium With Chemotherapy and Radiation Therapy for the Treatment of… | Phase 1 | terminated | Mar 23, 2004 | Pharmacyclics LLC. | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Dec 3, 2012source: clinicaltrials