Clinical trial · Observational
An Exploratory Study on Optical Assessment of Oral Mucositis
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Terminated due to slow accrual.
Summary
Brief summary (as posted)
Objectives: 1. To assess the tolerability of performing optical coherence tomography and/or optical spectroscopy in patients with acute oral mucositis. 2. To determine the feasibility of obtaining optical coherence tomography images and/or fluorescence excitation emission matrices from normal and affected sites in patients with acute oral mucositis. 3. To compare optical data obtained with optical coherence tomography and/or spectroscopy with the clinical appearance and scoring of oral mucositis lesions.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
| Oral Mucositis | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Fluorescence Spectroscopy | Procedure | — | UNRESOLVED |
| Optical Coherence Tomography | Procedure | — | UNRESOLVED |
| Pain Scale Questionnaire | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- OCT + FS + Questionnaire
- description
- Optical Coherence Tomography (OCT) + Fluorescence Spectroscopy (FS) and Questionnaire
- interventionNames
- Procedure: Optical Coherence Tomography
- Procedure: Fluorescence Spectroscopy
- Behavioral: Pain Scale Questionnaire
Primary outcomes (1)
- measure
- Optical assessment of oral mucositis in patients undergoing radiation or chemoradiation for head and neck cancer treatment
- timeFrame
- Two sets of oral scans; one at baseline and the second 2 weeks into therapy
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients greater than 18 years old. 2. Patients undergoing radiation therapy or chemoradiotherapy for head and neck cancer treatment. 3. Subject must sign an informed consent indicating awareness of the investigational nature of this study.
References
Publications (0)
Data not yet available