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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
2,225 stopped studies mapped to Malignant Genitourinary System Neoplasm and descendants · 88% state a reason
Over the 2,225 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00133224 | Docetaxel in Combination With GVAX ® Immunotherapy Versus Docetaxel and Prednisone in… | Phase 3 | terminated | Aug 23, 2005 | Cell Genesys | Accrual and treatment with CG1940/CG8711 stopped due to IDMC recommendation. | Enrollment / accrual |
| NCT00104130 | Study of KOS-862 (Epothilone D) in Metastatic Prostate Cancer | Phase 2 | terminated | Feb 24, 2005 | Bristol-Myers Squibb | not stated | Not stated |
| NCT00451945 | New Indications for Ultrasound in the Staging of Cervical Cancer | N/A | withdrawn | Mar 26, 2007 | Rigshospitalet, Denmark | not stated | Not stated |
| NCT00216814 | Antiangiogenic Effects of BCG on Urinary Concentration of Angiogenic Factors | — | terminated | Sep 22, 2005 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | No funding and data was not appropriate to consider continuing. | Funding |
| NCT00417677 | A Study Combining Treatment With Temsirolimus and Sunitinib for Subjects With Advanced… | Phase 1 / Phase 2 | terminated | Jan 4, 2007 | Wyeth is now a wholly owned subsidiary of Pfizer | Decision was made not to attempt a lower dose | Other (stated, no rule matched) |
| NCT00050375 | Clinical Trial for Ovarian Cancer (OvaRex®) | Phase 3 | terminated | Dec 6, 2002 | Unither Pharmaceuticals | Study closed by sponser | Other (stated, no rule matched) |
| NCT00086632 | Study of Ovarex® (Oregovomab) MAb With Front-Line Chemotherapy for Ovarian Cancer… | Phase 2 | terminated | Jul 9, 2004 | Unither Pharmaceuticals | closed by sponser | Other (stated, no rule matched) |
| NCT00131651 | ATN-161 in Advanced Renal Cell Cancer | Phase 2 | terminated | Aug 19, 2005 | Attenuon | not stated | Not stated |
| NCT00273338 | DN-101 in Combination With Docetaxel in Androgen-Independent Prostate Cancer (AIPC) (AIPC… | Phase 3 | terminated | Jan 9, 2006 | Novacea | DSMB | Other (stated, no rule matched) |
| NCT00047632 | Safety and Efficacy of Interferon Gamma-1b Plus Chemotherapy for Ovarian and Peritoneal… | Phase 3 | terminated | Oct 11, 2002 | InterMune | futility | Efficacy / futility |
| NCT00255268 | CMAB vs IMAB in Metastatic Prostate Cancer | Phase 4 | withdrawn | Nov 18, 2005 | AstraZeneca | not stated | Not stated |
| NCT00189579 | Addition of Herceptin to a Carboplatin-Paclitaxel Regimen in Patients With Ovarian Cancer | Phase 2 | terminated | Sep 19, 2005 | ARCAGY/ GINECO GROUP | not stated | Not stated |
| NCT00106262 | Study of Velcade and Irinotecan in Advanced Cervical, Vulvar, or Vaginal Cancer | Phase 2 | terminated | Mar 22, 2005 | Women and Infants Hospital of Rhode Island | Lack of accrual | Enrollment / accrual |
| NCT00287482 | Essiac (ESIAK) Versus Placebo to Improve Quality of Life in Transition in Women With… | N/A | terminated | Feb 6, 2006 | Women and Infants Hospital of Rhode Island | not stated | Not stated |
| NCT00132756 | Liposomal Doxorubicin and Estramustine Phosphate: Study in Taxane Resistant, Hormone… | Phase 1 / Phase 2 | terminated | Aug 22, 2005 | Morton Plant Mease Health Care | not stated | Not stated |
| NCT00103623 | The Plenaxis® Experience Study | Phase 4 | suspended | Feb 14, 2005 | PRAECIS Pharmaceuticals Inc. | not stated | Not stated |
| NCT00055432 | Gemzar (Gemcitabine) and Alimta (Pemetrexed) in the Treatment of Patients With Recurrent… | Phase 2 | terminated | Mar 4, 2003 | Eli Lilly and Company | not stated | Not stated |
| NCT00194935 | Weekly Topotecan Therapy in Patients With Ovarian Cancer | Phase 2 | terminated | Sep 19, 2005 | Weill Medical College of Cornell University | not stated | Not stated |
| NCT00220532 | Folate and Protection Against Cervical Cancer | Phase 1 / Phase 2 | terminated | Sep 22, 2005 | Sheffield Teaching Hospitals NHS Foundation Trust | not stated | Not stated |
| NCT00127088 | Study of Peri-Operative Docetaxel Plus Laparoscopic Radical Prostatectomy in Prostate… | Phase 2 | suspended | Aug 5, 2005 | Gustave Roussy, Cancer Campus, Grand Paris | not stated | Not stated |
| NCT00179725 | Phase I/II Open-Label, Dose Escalation Study To Determine The Maximum Tolerated Dose And… | Phase 1 / Phase 2 | terminated | Sep 16, 2005 | Celgene Corporation | not stated | Not stated |
| NCT00103428 | Intravenous CG7870 in Combination With Docetaxel in Patients With Metastatic… | Phase 1 / Phase 2 | terminated | Feb 9, 2005 | Cell Genesys | not stated | Not stated |
| NCT00151645 | Efficacy of Activated Lymphocytes in Renal Cell Carcinoma. | Phase 2 | terminated | Sep 9, 2005 | Rennes University Hospital | not stated | Not stated |
| NCT00179738 | A Multicenter, Single-Arm, Open-Label, Study to Evaluate the Safety and Efficacy of… | Phase 2 | terminated | Sep 16, 2005 | Celgene Corporation | not stated | Not stated |
| NCT00189371 | Reinduction Chemotherapy Containing Carboplatin and Paclitaxel With or Without Epoetin… | Phase 3 | terminated | Sep 19, 2005 | AGO Study Group | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Sep 23, 2008source: clinicaltrials