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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
826 stopped studies mapped to Malignant Female Reproductive System Neoplasm and descendants · 86% state a reason
Over the 826 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01069120 | Safety of 25 and 50 mg Proellex® in the Treatment of Women With Symptomatic Uterine… | Phase 3 | terminated | Feb 17, 2010 | Repros Therapeutics Inc. | Repros stopped study due to safety and FDA placed study on hold | Safety / toxicity |
| NCT01606358 | Influence of Chemotherapy on Gamma-delta T Cells in Patients With Epithelial Ovarian…(IClyCO) | — | withdrawn | May 25, 2012 | Rennes University Hospital | not stated | Not stated |
| NCT01550380 | BKM120 in Advanced, Metastatic, or Recurrent Endometrial Cancers(BKM120) | Phase 2 | withdrawn | Mar 12, 2012 | University of Utah | not stated | Not stated |
| NCT00610662 | Digital Colposcopy in Finding Cervical Intraepithelial Neoplasia in Patients With An… | — | withdrawn | Feb 8, 2008 | British Columbia Cancer Agency | Study modified and has been running as CDR0000581286 instead. | Other (stated, no rule matched) |
| NCT00626561 | Bevacizumab and Paclitaxel for Neuroendocrine Tumors of the Cervix | Phase 2 | terminated | Feb 29, 2008 | M.D. Anderson Cancer Center | Due to slow accrual. | Enrollment / accrual |
| NCT00874302 | Safety and Efficacy of 25 and 50 mg Doses of Proellex® in Treating the Recurrence of… | Phase 3 | withdrawn | Apr 2, 2009 | Repros Therapeutics Inc. | Study terminated for safety and the FDA put the study on hold for safety. | Safety / toxicity |
| NCT00418093 | Oxaliplatin, Gemcitabine and Bevacizumab in Women With Recurrent Mullerian Carcinoma | Phase 2 | terminated | Jan 4, 2007 | Dana-Farber Cancer Institute | THe study was terminated early due to a lack of accural | Other (stated, no rule matched) |
| NCT00835679 | Cetuximab and/or Dasatinib in Patients With Colorectal Cancer and Liver Metastases That… | Early Phase 1 | terminated | Feb 4, 2009 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00003094 | Carotenoid Rich Diet in Treating Cervical Dysplasia | Phase 2 | withdrawn | Apr 27, 2004 | University of California, San Diego | Study was halted prematurely, prior to enrollment of first participant | Enrollment / accrual |
| NCT01233505 | Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumors | Phase 1 | terminated | Nov 3, 2010 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01613521 | Tumor Perfusion and Hypoxia Assessed by DCE-MRI and 18F-FMISO PET as Biomarkers of… | N/A | terminated | Jun 7, 2012 | Memorial Sloan Kettering Cancer Center | Lack of accrual | Enrollment / accrual |
| NCT00967928 | Everolimus Dose Finding Study for Stage IV or Recurrent Cervical Cancer | Phase 1 | withdrawn | Aug 28, 2009 | Accelerated Community Oncology Research Network | Lack of enrollment | Enrollment / accrual |
| NCT01403103 | Cholecalciferol(25-[OH]-Vitamin D) in Treating Patients With Colorectal Cancer | Early Phase 1 | withdrawn | Jul 27, 2011 | Case Comprehensive Cancer Center | Slow Accrual | Enrollment / accrual |
| NCT01202890 | Study of Revlimid With Doxil and Avastin for Patients With Platinum Resistant Ovarian… | Phase 1 | terminated | Sep 16, 2010 | New Mexico Cancer Research Alliance | Terminated due to inadequate rate of accrual. | Enrollment / accrual |
| NCT01131039 | Safety and Efficacy Study of Gemcitabine Plus Bevacizumab in Patients With… | Phase 2 | withdrawn | May 26, 2010 | Emory University | PI left Emory | Investigator |
| NCT01982487 | Vaccine Therapy and IDO1 Inhibitor INCB024360 in Treating Patients With Epithelial… | Phase 1 / Phase 2 | withdrawn | Nov 13, 2013 | Roswell Park Cancer Institute | not stated | Not stated |
| NCT00768742 | Safety and Effectiveness Study of RF Ablation of Uterine Fibroids to Reduce Menstrual…(FAST) | N/A | withdrawn | Oct 8, 2008 | Gynesonics | study revised and reinitiated under another protocol | Other (stated, no rule matched) |
| NCT00138151 | Isotretinoin, Interferon Alpha-2b, and Paclitaxel in Stage IV, Recurrent, or Persistent… | Phase 2 | terminated | Aug 30, 2005 | University of Medicine and Dentistry of New Jersey | Slow accrual and lack of study drug | Enrollment / accrual |
| NCT00053833 | S0025 Irinotecan in Treating Patients With Refractory Ovarian Epithelial, Primary… | Phase 2 | terminated | Feb 6, 2003 | SWOG Cancer Research Network | lack of accrual | Enrollment / accrual |
| NCT00072540 | S0212 Celecoxib in Treating Patients With High-Grade Squamous Intraepithelial Lesions of… | Phase 2 | withdrawn | Nov 5, 2003 | SWOG Cancer Research Network | drug issues | Other (stated, no rule matched) |
| NCT01743547 | The Effects Of Yoga On Quality Of Life Among A Population Of Ovarian/ Fallopian Tube/… | N/A | terminated | Dec 6, 2012 | Northwestern University | The investigators concluded that it is not feasible due to the lack of participation and difficulty… | Enrollment / accrual |
| NCT00907634 | Prospective Evaluation of Intrafractional and Interfractional Cervical Motion During… | — | withdrawn | May 22, 2009 | Emory University | Study closed by IRB because a Continuing Review and/or Close-Out have not been submitted. Study… | Other (stated, no rule matched) |
| NCT00085631 | Cisplatin and Radiation Therapy With or Without Hyperthermia Therapy in Treating Patients… | Phase 3 | terminated | Jun 11, 2004 | Mark Dewhirst | Study was closed because of slow accrual | Enrollment / accrual |
| NCT00382330 | Chemoprevention of Cancer in the Lower Female Genital Tract: The Antineoplastic Activity… | N/A | withdrawn | Sep 29, 2006 | University of Medicine and Dentistry of New Jersey | not stated | Not stated |
| NCT00085527 | FR901228 in Treating Patients With Relapsed or Refractory Advanced Ovarian Epithelial… | Phase 2 | withdrawn | Jun 11, 2004 | University of Chicago | not stated | Not stated |
| NCT01321697 | A Non-Randomized Study to Evaluate Leg Lymphatic Drainage Associated With Surgical… | — | terminated | Mar 23, 2011 | University of Arkansas | Principal Investigator Request | Investigator |
| NCT00084370 | Celecoxib in Preventing Cancer in Patients at High Risk for Ovarian Epithelial Cancer Who… | N/A | withdrawn | Jun 11, 2004 | University of Alabama at Birmingham | not stated | Not stated |
| NCT01010334 | Comparison of Standard of Care or Treatment on Protocol | N/A | terminated | Nov 10, 2009 | New Mexico Cancer Research Alliance | PI deparature and very low (\<2%) accrual rate.(No results required) | Enrollment / accrual |
| NCT00017537 | Vaccine Therapy in Treating Patients With Metastatic or Recurrent Cancer | Phase 1 | withdrawn | Jan 8, 2004 | University of Alabama at Birmingham | not stated | Not stated |
| NCT00080639 | CA-125 in Screening Patients at High Risk for Ovarian Cancer | — | withdrawn | Apr 8, 2004 | University of Alabama at Birmingham | Terminated for administrative reasons and becuase there were no enrollments | Enrollment / accrual |
| NCT01821859 | Abraxane/Bevacizumab | Phase 2 | terminated | Apr 1, 2013 | OHSU Knight Cancer Institute | Terminated due to low enrollment | Enrollment / accrual |
| NCT00942838 | Whole Abdomen Radiation in Conjunction With Intraperitoneal Chemotherapy for the…(WAR) | Phase 1 | withdrawn | Jul 21, 2009 | University of Utah | PI decision due to under accrual. | Enrollment / accrual |
| NCT01498237 | Photoacoustic Endoscopy in Endometrial Cancer | Early Phase 1 | withdrawn | Dec 23, 2011 | Washington University School of Medicine | Need to obtain IDE prior to commencement of study | Other (stated, no rule matched) |
| NCT00566644 | Intrauterine Levonorgestrel and Observation or Observation Alone in Preventing Atypical… | Phase 3 | terminated | Dec 3, 2007 | St George's, University of London | Withdrawn due to poor accrual | Enrollment / accrual |
| NCT00748527 | Carboplatin With or Without Decitabine in Treating Patients With Progressive, Advanced… | Phase 2 | terminated | Sep 8, 2008 | Cancer Research UK | The study was "withdrawn" due to certain adverse events \[hypersensitivity\]. | Safety / toxicity |
| NCT00003378 | Combination Chemotherapy in Treating Patients With Previously Untreated Stage III or… | Phase 1 | terminated | Aug 26, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00006267 | Nitrocamptothecin in Treating Patients With Recurrent or Metastatic Ovarian Epithelial or… | Phase 2 | withdrawn | Jan 27, 2003 | Gynecologic Oncology Group | Never activated. | Other (stated, no rule matched) |
| NCT00084448 | Paclitaxel and Celecoxib in Treating Patients With Recurrent or Persistent… | Phase 2 | terminated | Jun 11, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00002478 | Etoposide in Treating Patients With Advanced Ovarian or Cervical Cancer | Phase 2 | terminated | Jun 9, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003179 | Surgery Plus Medroxyprogesterone in Preventing Endometrial Cancer | Phase 2 | terminated | Jan 27, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003380 | Liposomal Doxorubicin and Etoposide in Treating Patients With Recurrent or Persistent… | Phase 1 | terminated | Aug 16, 2004 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003382 | Combination Chemotherapy Consisting of Gemcitabine And Topotecan in Treating Patients… | Phase 1 | terminated | Jul 15, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003794 | Quality-of-Life Study of Patients With Previously Treated Ovarian Cancer | — | terminated | Oct 29, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00006096 | Radiation Therapy With or Without Cisplatin in Treating Patients With Stage I, Stage II,… | Phase 3 | terminated | Sep 3, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00017134 | Fenretinide Followed by Surgery Compared With Surgery Alone in Preventing Ovarian Cancer… | N/A | terminated | May 7, 2003 | Gynecologic Oncology Group | Withdrawn due to poor accrual | Enrollment / accrual |
| NCT00369954 | Gemcitabine and Carboplatin in Treating Patients With Persistent or Recurrent Ovarian… | Phase 2 | withdrawn | Aug 30, 2006 | Gynecologic Oncology Group | Trial was never activated | Other (stated, no rule matched) |
| NCT00477867 | Economic Outcomes in Patients With Stage III Ovarian Cancer Receiving Paclitaxel and… | N/A | withdrawn | May 24, 2007 | Gynecologic Oncology Group | Trial was never activated | Other (stated, no rule matched) |
| NCT00583622 | Bevacizumab Plus Gemcitabine, Docetaxel, Melphalan, and Carboplatin in Ovarian Cancer… | Phase 2 | terminated | Dec 31, 2007 | M.D. Anderson Cancer Center | Slow Accrual | Enrollment / accrual |
| NCT01383408 | Distinction Between Lung Cancer and Gynecological Cancers by Canine Scent Detection | Phase 2 | terminated | Jun 28, 2011 | Schillerhoehe Hospital | Inconsistent training status of sniffer dogs | Other (stated, no rule matched) |
| NCT00002819 | Chemotherapy With or Without Peripheral Stem Cell Transplantation in Treating Patients… | Phase 3 | terminated | May 26, 2004 | Gynecologic Oncology Group | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Aug 21, 2014source: clinicaltrials