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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
207 stopped studies mapped to Malignant Cervical Neoplasm and descendants · 84% state a reason
Over the 207 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT01285102 | Chemoembolization Using Irinotecan in Treating Patients With Liver Metastases From… | Phase 1 | terminated | Jan 27, 2011 | Fox Chase Cancer Center | This study was closed early by the DSMB due to increased toxicity. | Safety / toxicity |
| NCT03328013 | Impact of HPV Vaccination to Catch up in the Emergence of Lesions of the Cervix(HPVAC) | — | terminated | Nov 1, 2017 | University Hospital, Brest | manager's decision | Other (stated, no rule matched) |
| NCT01902966 | Feasibility - Beta Adrenergic Blockade (BB) in Cervical Cancer (CX) | N/A | terminated | Jul 18, 2013 | M.D. Anderson Cancer Center | low accrual and lack of funding | Enrollment / accrual |
| NCT04099277 | A Study of LY3435151 in Participants With Solid Tumors | Phase 1 | terminated | Sep 23, 2019 | Eli Lilly and Company | Study terminated due to strategic business decision by Eli Lilly and Company. | Sponsor / business decision |
| NCT00911079 | Pilot Study of a Catheter-based Ultrasound Hyperthermia System | N/A | terminated | Jun 1, 2009 | University of California, San Francisco | Low Accrual | Enrollment / accrual |
| NCT00978874 | Fluorine F 18 EF5 PET/CT Imaging in Patients With Locally Advanced or… | N/A | terminated | Sep 17, 2009 | Abramson Cancer Center at Penn Medicine | The PI is no longer with our institution | Other (stated, no rule matched) |
| NCT00577317 | Flexitouch® Home Maintenance Therapy or Standard Home Maintenance Therapy in Treating… | Phase 3 | terminated | Dec 20, 2007 | Gynecologic Oncology Group | not stated | Not stated |
| NCT03786107 | HER-Seq: A Blood-based Screening Study to Identify Patients With HER2 Mutations for… | — | terminated | Dec 24, 2018 | Puma Biotechnology, Inc. | The study was stopped early due to increased global access to genomic screening. It is no longer… | Other (stated, no rule matched) |
| NCT04498520 | Abexinostat, Palbociclib, and Fulvestrant for the Treatment of Breast or Gynecologic… | Phase 1 | withdrawn | Aug 4, 2020 | Pamela Munster | Funding | Funding |
| NCT04464967 | Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in… | Phase 1 / Phase 2 | withdrawn | Jul 9, 2020 | NKGen Biotech, Inc. | Trial not initiated | Other (stated, no rule matched) |
| NCT01016561 | Magnetic Resonance Imaging-Based Radiation Therapy and Cisplatin in Patients With Stage… | N/A | terminated | Nov 19, 2009 | Abramson Cancer Center at Penn Medicine | Poor accrual/enrollments | Enrollment / accrual |
| NCT03902379 | Web-Based Coping and Communication Skills Intervention in Improving Psychological… | N/A | withdrawn | Apr 4, 2019 | Rutgers, The State University of New Jersey | The study was never initiated, no patients were enrolled. It has been closed with the IRB. | Enrollment / accrual |
| NCT01097239 | Examining the Role of Transrectal High Intensity Focused Ultrasound (HIFU) in Rectal… | Phase 1 / Phase 2 | withdrawn | Apr 1, 2010 | Imperial College London | Failure to recruit. | Enrollment / accrual |
| NCT03423082 | Pilot Study to Assess the Potential Clinical Utility of 18F Fluciclovine PET for Cervical… | Phase 4 | terminated | Feb 6, 2018 | Nghi Nguyen | Limited subject enrollment | Enrollment / accrual |
| NCT02045433 | Stereotactic Body Radiation Therapy (SABR) for Definitive Treatment of Locally Advanced… | Phase 2 | terminated | Jan 24, 2014 | University of Texas Southwestern Medical Center | The study was prematurely closed due to unacceptable toxicity. | Safety / toxicity |
| NCT02317302 | FDG Tumor Heterogeneity During Chemoradiation as a Predictor of Response in Patients With… | Phase 1 | terminated | Dec 16, 2014 | Washington University School of Medicine | Insufficient funding | Funding |
| NCT03318107 | Ultrasound and Photoacoustic Imaging for Cervical Cancer | N/A | terminated | Oct 23, 2017 | Washington University School of Medicine | Low accrual | Enrollment / accrual |
| NCT01019278 | Proton Beam Radiation Therapy and Cisplatin in Treating Patients With Stage IB, Stage II,… | Phase 2 | withdrawn | Nov 24, 2009 | Abramson Cancer Center at Penn Medicine | not stated | Not stated |
| NCT03644459 | Safety and Efficacy of the Fully Humanized Anti - VEGF Monoclonal Antibody LYN00101 | Phase 1 | withdrawn | Aug 23, 2018 | Lynkcell Inc. | Unable to recruit individuals for the study | Enrollment / accrual |
| NCT01392352 | HYPAZ: Hypertension Induced by Pazopanib(HYPAZ) | Phase 2 | terminated | Jul 12, 2011 | Cambridge University Hospitals NHS Foundation Trust | Following DMC review, due to slow recruitment of evaluable patients. | Enrollment / accrual |
| NCT03146039 | Non-Invasive Cervical Cancer Radiotherapy for Stage IB-IVB(NICER) | Phase 2 | withdrawn | May 9, 2017 | University of California, San Diego | Patient enrollment goal will not be met | Enrollment / accrual |
| NCT04125225 | What Are the Experiences of Patients With Pseudomyxoma Peritonei? | — | withdrawn | Oct 14, 2019 | University of Southampton | No participants enrolled. | Enrollment / accrual |
| NCT03852979 | Neo-Adjuvant Chemotherapy and Conservative Surgery in Cervical Cancer to Preserve…(NEOCON-F) | Phase 2 | terminated | Feb 25, 2019 | The Netherlands Cancer Institute | study is merged with CONTESSA study | Other (stated, no rule matched) |
| NCT00394602 | Chemoradiation-Induced Nausea and Emesis: Quality of Life | — | terminated | Nov 1, 2006 | M.D. Anderson Cancer Center | Requested by PI during yearly Continuing Review | Other (stated, no rule matched) |
| NCT00519272 | A Prospective Study Examining the Barriers to Care for Harris County Cervical Cancer… | — | terminated | Aug 22, 2007 | M.D. Anderson Cancer Center | Requested by PI during yearly Continuing Review | Other (stated, no rule matched) |
| NCT00924066 | Ixabepilone to Treat Cervical Cancer | Phase 2 | terminated | Jun 18, 2009 | National Cancer Institute (NCI) | Premature closure due to slow/insufficient accrual. | Enrollment / accrual |
| NCT00204997 | Preservation of Ovarian Function Via LOT in Squamous Cell Carcinoma of the Cervix | N/A | terminated | Sep 20, 2005 | University of Wisconsin, Madison | slow accrual | Enrollment / accrual |
| NCT03795272 | Rucaparib Maintenance Therapy in Advanced Cervical Cancer(MaRuC) | Phase 2 | withdrawn | Jan 7, 2019 | Nordic Society of Gynaecological Oncology - Clinical Trials Unit | Lack of financial support | Funding |
| NCT01583686 | CAR T Cell Receptor Immunotherapy Targeting Mesothelin for Patients With Metastatic Cancer | Phase 1 / Phase 2 | terminated | Apr 24, 2012 | National Cancer Institute (NCI) | Study terminated due to slow/insufficient accrual. | Enrollment / accrual |
| NCT03613493 | Acceptability of Human Papillomavirus (HPV) Self-sampling Tools for Cervical Cancer… | N/A | terminated | Aug 3, 2018 | University of Miami | Budgetary and Timing Constraints | Funding |
| NCT00262821 | Cisplatin and Radiation Therapy With or Without Tirapazamine in Treating Patients With… | Phase 3 | terminated | Dec 7, 2005 | National Cancer Institute (NCI) | Study drug no longer available resulting in lack of study drug for participants. | Other (stated, no rule matched) |
| NCT02558348 | Phase 1/2a Evaluation of AL3818 in Subjects With Recurrent or Metastatic Endometrial,…(AL3818) | Phase 1 / Phase 2 | terminated | Sep 24, 2015 | Advenchen Laboratories, LLC | Sponsor termination | Other (stated, no rule matched) |
| NCT02153905 | T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who… | Phase 1 / Phase 2 | terminated | Jun 3, 2014 | National Cancer Institute (NCI) | Slow, insufficient accrual. | Enrollment / accrual |
| NCT01958112 | GSK1120212+GSK2141795 for Cervical Cancer | Phase 2 | terminated | Oct 8, 2013 | Dana-Farber Cancer Institute | Drug supply | Drug supply |
| NCT00257829 | Improving Tumor Oxygenation in Cervical Cancer | Phase 2 | withdrawn | Nov 23, 2005 | University of California, Irvine | This study was closed due to lack of funding. | Funding |
| NCT02868892 | A Study of Pemetrexed in Recurrent Cervical Adenocarcinomas | Phase 2 | terminated | Aug 16, 2016 | Western Regional Medical Center | departure of PI from institution and poor population for study participation | Other (stated, no rule matched) |
| NCT03220009 | Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in… | Phase 2 | withdrawn | Jul 18, 2017 | National Cancer Institute (NCI) | The study was never approved by CTEP neither was it ever activated | Other (stated, no rule matched) |
| NCT00084890 | Docetaxel and Carboplatin in Treating Patients With Recurrent Stage IVB Squamous Cell… | Phase 1 | terminated | Jun 11, 2004 | Wake Forest University Health Sciences | slow accrual | Enrollment / accrual |
| NCT01197664 | Paricalcitol, Fluorouracil, and Radiation Therapy in Treating Patients With Rectal Cancer… | Phase 1 | terminated | Sep 9, 2010 | Wake Forest University Health Sciences | Study terminated due to funding issues | Funding |
| NCT00899093 | YKL-40 in Serum Samples From Patients With Newly Diagnosed Stage III-IV Ovarian… | — | terminated | May 12, 2009 | Gynecologic Oncology Group | not stated | Not stated |
| NCT01275664 | Granisetron, Aprepitant, and Dexamethasone in Preventing Nausea and Vomiting in Patients… | N/A | terminated | Jan 12, 2011 | Gynecologic Oncology Group | Study terminated due to no patient population available | Other (stated, no rule matched) |
| NCT02412124 | Peer-to-Peer Support Program in Improving Quality of Life Outcomes in Patients With… | N/A | terminated | Apr 8, 2015 | City of Hope Medical Center | Feasibility issues | Other (stated, no rule matched) |
| NCT02110953 | Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal… | Phase 1 | terminated | Apr 10, 2014 | Fox Chase Cancer Center | IRB study closure by investigator due to low enrollment | Investigator |
| NCT00004261 | EF5 Prior to Surgery or Biopsy in Patients With Breast, Prostate, or Cervical Cancer or… | Phase 1 | terminated | Dec 11, 2003 | University Health Network, Toronto | Lack of patient accrual | Enrollment / accrual |
| NCT01934179 | Telomere Length in Predicting Toxicity in Older Patients With Stage III-IV Colorectal… | — | terminated | Sep 4, 2013 | Fox Chase Cancer Center | Low Accrual Rate | Enrollment / accrual |
| NCT01575444 | Cervical Cancer Screening Project Part C | — | terminated | Apr 11, 2012 | University of Minnesota | Investigator left University No results are possible | Investigator |
| NCT00428194 | Erlotinib, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB-Stage IVA… | Phase 1 | withdrawn | Jan 29, 2007 | Masonic Cancer Center, University of Minnesota | Withdrawn due to lack of accrual | Enrollment / accrual |
| NCT00278434 | Zoledronate in Treating Patients With Cervical Intraepithelial Neoplasia 2/3 or 3 | Phase 1 | terminated | Jan 18, 2006 | University of California, San Francisco | Accrual was insufficient to meet study endpoints | Enrollment / accrual |
| NCT00070317 | Lymph Node Mapping and Sentinel Lymph Node Identification in Patients With Stage IB1… | N/A | terminated | Oct 7, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT03007771 | Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild… | Phase 1 | withdrawn | Jan 2, 2017 | Washington University School of Medicine | Decision was made to not go forward with the study | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 23 days agoSource updated Dec 20, 2021source: clinicaltrials