Clinical trial · Observational
Identification and Characterization of Molecular Markers in Musculoskeletal Tumors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Principal Investigator has left the Institution
Summary
Brief summary (as posted)
The aim of the study is to improve the understanding of molecular mechanisms in the development and progression of musculoskeletal tumors. These tumors do have in general unfavorable prognosis and conventional treatments (e.g. surgery, radiotherapy or chemotherapy) could not enhance the prognosis of these patients during the last ten to fifteen years. Therefore the investigators chose a new way, as they try to identify markers on a genetic level, who ideally act as a basis to develop new treatment options.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Sarcoma | Sarcoma | ONTOLOGY_EXACT | 0.98 |
| Sarcoma of Bone | Bone Sarcoma | ALIAS | 0.90 |
| Soft Tissue and Bone Tumors | Connective and Soft Tissue Neoplasm | ALIAS | 0.90 |
| Soft Tissue Sarcoma | Soft Tissue Sarcoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Identification and characterization of molecular markers in musculoskeletal tumors | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- musculoskeletal tumors
- description
- Patients with suspected or confirmed bone or soft tissue tumors undergoing biopsy or surgery
- interventionNames
- Other: Identification and characterization of molecular markers in musculoskeletal tumors
Primary outcomes (1)
- measure
- Tumor RNA in resected tissue
- timeFrame
- at time of surgery
Secondary outcomes (2)
- measure
- Cell free tumor RNA in blood plasma
- timeFrame
- 7 to 1 day before surgery
- measure
- Cell free tumor RNA in blood plasma
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * surgery or biopsy of a bone- or soft tissue tumor * informed consent Exclusion Criteria: * patients wish
References
Publications (0)
Data not yet available