Terminated, withdrawn and suspended trials

clinicaltrialsObservedShowing 101–150 of 200 studies, most recently updated first

NCT	Title	Phase	Status	First posted	Lead sponsor	Why stopped (as posted)	Category
NCT03258541	Organ-sparing With TraceIT® for Rectal Cancer Radiotherapy	N/A	terminated	Aug 23, 2017	Thomas Zilli	Surgical access not facilitated- residues of hydrogel.	Other (stated, no rule matched)
NCT02052921	Observation Versus Surgical Resection in Patients With Rectal Cancer Who Achieved…	N/A	terminated	Feb 3, 2014	Instituto do Cancer do Estado de São Paulo	During the execution time foreseen in the project, the expected number of patients was not reached.	Other (stated, no rule matched)
NCT03487484	Quality of Life in Patients With Rectal Cancer Receiving Total Mesorectal Excision With…	—	terminated	Apr 4, 2018	University Hospital, Basel, Switzerland	insufficient recruitment	Enrollment / accrual
NCT00353457	Capecitabine,Oxaliplatin & Erbitux Given Throughout Multi-Modal Therapy for Locally…	Phase 2	terminated	Jul 18, 2006	Abramson Cancer Center at Penn Medicine	new studies were finding that Erbitux was not beneficial	Other (stated, no rule matched)
NCT00207831	Trial Testing Ftorafur (UFT) Associated With Neoadjuvant Radiotherapy Versus Radiotherapy…(UFT RT Phase 3)	Phase 3	terminated	Sep 21, 2005	Institut Cancerologie de l'Ouest	Terminated after interim analysis	Efficacy / futility
NCT02797405	Tumour and HEalthy Tissues DOse-response and Radiosensitivity Assay(THEODORA)	N/A	terminated	Jun 13, 2016	Centre Leon Berard	Withdrawal of analysis study Partner.	Other (stated, no rule matched)
NCT03049124	Exercise for Adults Diagnosed With Rectal Cancer	N/A	withdrawn	Feb 9, 2017	University of Ottawa	We were unable to enroll participants into the study.	Enrollment / accrual
NCT01671488	A Phase I/II Evaluation of ADXS11-001, Mitomycin, 5-fluorouracil (5-FU) and IMRT for Anal…(276)	Phase 1 / Phase 2	terminated	Aug 23, 2012	Brown University	pilot data to be used for upcoming larger trial.	Other (stated, no rule matched)
NCT03413930	Transanal Versus Laparoscopic Total Mesorectal Excision for Rectal Cancer	N/A	withdrawn	Jan 29, 2018	Ruijin Hospital	No funding was raised	Funding
NCT00955240	Radiation Therapy, Cisplatin, Fluorouracil, and Cetuximab in Treating Patients With…	Phase 2	terminated	Aug 10, 2009	UNICANCER	Inadequate toxicity	Safety / toxicity
NCT02425683	Study of Colorectal Cancer Patients (Stage IIIC) With Either Regorafenib or Standard of…	Phase 2	terminated	Apr 24, 2015	US Oncology Research	insufficient accrual	Enrollment / accrual
NCT00394602	Chemoradiation-Induced Nausea and Emesis: Quality of Life	—	terminated	Nov 1, 2006	M.D. Anderson Cancer Center	Requested by PI during yearly Continuing Review	Other (stated, no rule matched)
NCT00580073	Phase II Trial of Neoadjuvant FOLFOX4 and Cetuximab for Localized Adenocarcinoma of Rectum	Phase 2	terminated	Dec 24, 2007	University of Wisconsin, Madison	Loss of funding	Funding
NCT02290574	Efficacy of NeoThermo-Radio-chemotherapy for LA Rectal Cancer Before Laparoscopic TME:…(NEOTREAT)	N/A	terminated	Nov 14, 2014	Samsung Medical Center	slow accrual	Enrollment / accrual
NCT00397878	AZD0530 (NSC 735464) in Treating Patients With Previously Treated Metastatic Colon Cancer…	Phase 2	terminated	Nov 10, 2006	National Cancer Institute (NCI)	The study was terminated after all enrolled participants progressed.	Enrollment / accrual
NCT02233595	Evaluation of Rectal Cancer Treatment Response Using PET/MRI(Rectal PET/MRI)	—	terminated	Sep 8, 2014	University of California, San Francisco	Low Accrual	Enrollment / accrual
NCT03204201	Validation of ICG to Identify the Urethra During Rectal Surgery	Phase 1 / Phase 2	terminated	Jun 29, 2017	Oxford University Hospitals NHS Trust	Technique failed	Other (stated, no rule matched)
NCT03204994	Fluorescence Targeted Pelvic Lymph Node Mapping	Phase 1 / Phase 2	terminated	Jul 2, 2017	Oxford University Hospitals NHS Trust	Not able to recruit	Enrollment / accrual
NCT03161574	FOLFOXIRI Chemotherapy Alone as Neoadjuvant Treatment for Circumferential Radial Margin…	Phase 2	withdrawn	May 22, 2017	Guangxi Medical University	No participants were recruited	Enrollment / accrual
NCT03677960	Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human…	Phase 1	terminated	Sep 19, 2018	Antiva Biosciences	Pre-Clinical Toxicology Findings	Other (stated, no rule matched)
NCT02585271	Transanal Decompression Tube Versus Stent for Acute Malignant Left-sided Colonic and…	N/A	terminated	Oct 23, 2015	Xuzhou Central Hospital	We can not get enough sample size.	Other (stated, no rule matched)
NCT03634202	Study of Radiation Therapy in Combination With Xeloda, for Initially Metastatic, Low and…(DESIR)	N/A	terminated	Aug 16, 2018	Institut Cancerologie de l'Ouest	the study was stopped for lack of inclusion	Other (stated, no rule matched)
NCT00835055	Expression of Molecular Markers Before and After Neo-adjuvant Chemoradiotherapy in Rectal…	—	withdrawn	Feb 3, 2009	St. Claraspital AG	never started several reasons	Other (stated, no rule matched)
NCT00651677	Hand Assisted Versus "Pure" Laparoscopic Assisted Proctectomy for Rectal Cancer	N/A	withdrawn	Apr 3, 2008	Weill Medical College of Cornell University	funding issues	Funding
NCT00611858	Cetuximab, 5-FU and Radiation as Neoadjuvant Therapy for Patients With Locally Advanced…	Phase 2	terminated	Feb 11, 2008	Dana-Farber Cancer Institute	Slow accrual	Enrollment / accrual
NCT00267787	Molecular Genetic and Pathological Studies of Anal Tumors	—	terminated	Dec 21, 2005	Stanford University	not stated	Not stated
NCT01313026	Treatment of "Low Anterior Resection Syndrome" by Percutaneous Nerve Evaluation and…	N/A	terminated	Mar 11, 2011	University of Aarhus	Difficult to recruit participants	Enrollment / accrual
NCT03527784	Prestoma-Trial for Parastomal Hernia Prevention	N/A	terminated	May 17, 2018	University of Oulu	Parastomal Parietex withdrawn from market by the manufacturer.	Drug supply
NCT00254436	A Double-Blind, Randomized, Placebo-Controlled Study of the Efficacy and Safety of Weekly…	Phase 3	terminated	Nov 16, 2005	M.D. Anderson Cancer Center	not stated	Not stated
NCT02216149	Effects of S-1 and Capecitabine on Coronary Artery Blood Flow(FluoHeart)	Phase 2	terminated	Aug 13, 2014	Heikki Joensuu	Slow accrual	Enrollment / accrual
NCT00845039	A Study of Irinotecan and Cetuximab With or Without IMC-A12 for Treatment of Participants…(FC-4)	Phase 2	terminated	Feb 16, 2009	Eli Lilly and Company	Study terminated early 22Feb2010 with only 4 participants due to business reasons.	Sponsor / business decision
NCT01197664	Paricalcitol, Fluorouracil, and Radiation Therapy in Treating Patients With Rectal Cancer…	Phase 1	terminated	Sep 9, 2010	Wake Forest University Health Sciences	Study terminated due to funding issues	Funding
NCT01887509	Evaluation of Rectal Tumor Margin Using Confocal Endomicroscopy and Comparison to…(TRaMA)	N/A	terminated	Jun 27, 2013	IHU Strasbourg	Difficulties with patients recruitment, study acceptance and protocol implementation.	Enrollment / accrual
NCT00663819	Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal Anastomoses	N/A	terminated	Apr 22, 2008	W.L.Gore & Associates	Per SAP	Other (stated, no rule matched)
NCT01919541	Mechanistic Prehabilitation	N/A	withdrawn	Aug 9, 2013	Franco Carli	difficulty in recruiting patients	Enrollment / accrual
NCT02110953	Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal…	Phase 1	terminated	Apr 10, 2014	Fox Chase Cancer Center	IRB study closure by investigator due to low enrollment	Investigator
NCT01934179	Telomere Length in Predicting Toxicity in Older Patients With Stage III-IV Colorectal…	—	terminated	Sep 4, 2013	Fox Chase Cancer Center	Low Accrual Rate	Enrollment / accrual
NCT02163187	Sacral Neuromodulation (SNM) With InterStimTM for Bowel Dysfunction Following Surgery for…	Phase 2 / Phase 3	terminated	Jun 13, 2014	Memorial Sloan Kettering Cancer Center	Study permanently closed due to low accrual	Enrollment / accrual
NCT02407561	Prospective Validation Study for the Proprietary Rectal and Anal Cancer Protein…	—	terminated	Apr 3, 2015	Castle Biosciences Incorporated	Futility - unable to secure sites and samples for participation	Efficacy / futility
NCT01729923	A Trial of Maintenance ADAPT Therapy With Capecitabine and Celecoxib in Patients With…(ADAPT)	Phase 2	terminated	Nov 20, 2012	University of Washington	Funding ended	Funding
NCT00226941	A Phase 1-2 Trial of Cetuximab in Combination With Oxaliplatin, Capecitabine, and…	Phase 1 / Phase 2	terminated	Sep 27, 2005	George Albert Fisher	The response rate observed in the phase 1 portion of the study did not merit further evaluation in…	Other (stated, no rule matched)
NCT02057991	Mindfulness-Based Exercise Video in Educating Hispanic/Latino Patients With Colorectal…	N/A	terminated	Feb 7, 2014	University of Southern California	Insufficient Accrual	Enrollment / accrual
NCT00903396	Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy…	Phase 2	terminated	May 18, 2009	Alliance for Clinical Trials in Oncology	Slow accrual	Enrollment / accrual
NCT03007771	Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild…	Phase 1	withdrawn	Jan 2, 2017	Washington University School of Medicine	Decision was made to not go forward with the study	Other (stated, no rule matched)
NCT02609451	Closure of Protective Ileostomy 2 vs. 12 Weeks After TME(Closure2vs12)	N/A	terminated	Nov 20, 2015	Kantonsspital Liestal	Evidence of bad outcome after interims analysis	Other (stated, no rule matched)
NCT01270438	Combination Chemotherapy and Bevacizumab With or Without RO4929097 in Treating Patients…	Phase 2	withdrawn	Jan 5, 2011	National Cancer Institute (NCI)	not stated	Not stated
NCT02857608	A Prospective, Open-Label, Multi-center Comparison of Lymphoseek Identified Lymph Nodes…	Phase 2	withdrawn	Aug 5, 2016	Cardinal Health 414, LLC	not stated	Not stated
NCT02046538	Phase II Study of Zaltrap and Chemotherapy for Advanced Resectable Colorectal Cancer	Phase 2	withdrawn	Jan 27, 2014	Weill Medical College of Cornell University	Investigator terminated due to funding issues	Investigator
NCT02586610	Trial of Chemoradiation and Pembrolizumab in Patients With Rectal Cancer	Phase 2	withdrawn	Oct 26, 2015	Osama Rahma, MD	Dr. Rahma decided to run the study through a different group	Other (stated, no rule matched)
NCT02287727	Regorafenib in Reducing Recurrence in Patients With Non-metastatic Rectal Cancer Who Have…	Phase 2	withdrawn	Nov 11, 2014	Roswell Park Cancer Institute	not stated	Not stated

Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.

Data updated 23 days agoSource updated May 15, 2020source: clinicaltrials

Terminated, withdrawn and suspended studies

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