Terminated, withdrawn and suspended trials

clinicaltrialsObservedShowing 701–750 of 976 studies, most recently updated first

NCT	Title	Phase	Status	First posted	Lead sponsor	Why stopped (as posted)	Category
NCT03345225	A Clinical Study of Precision TACE (P-TACE) With Surefire	N/A	withdrawn	Nov 17, 2017	University of Miami	Funding	Funding
NCT02650635	TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients With Metastatic,…	Phase 1	terminated	Jan 8, 2016	Mayo Clinic	permanently closed per sponsor's request	Other (stated, no rule matched)
NCT03096899	A Study to Estimate Overall Survival in Patients Receiving Best Supportive Care for…	—	withdrawn	Mar 30, 2017	The Rogosin Institute	The investigator conducting the study determined that the entry criteria for the proposed subjects…	Investigator
NCT02216149	Effects of S-1 and Capecitabine on Coronary Artery Blood Flow(FluoHeart)	Phase 2	terminated	Aug 13, 2014	Heikki Joensuu	Slow accrual	Enrollment / accrual
NCT01425996	A Dose-escalation Study of Lipotecan® Plus Radiotherapy in Locally Advanced…	Phase 1 / Phase 2	terminated	Aug 30, 2011	Taiwan Liposome Company	not stated	Not stated
NCT02508077	FOLFIRI and Panitumumab in Treating Patients With RAS and BRAF Wild-Type Metastatic…	Phase 2	terminated	Jul 24, 2015	City of Hope Medical Center	Poor Accrual	Enrollment / accrual
NCT01608464	Pre-op Chemo-RT w/CDDP/5FU vs Chemo w/ Docetaxel/Irinotecan in PET Non Responder…	Phase 2	terminated	May 31, 2012	King Faisal Specialist Hospital & Research Center	poor accrual	Enrollment / accrual
NCT01921751	High or Standard Intensity Radiation Therapy After Gemcitabine Hydrochloride and…	Phase 2	terminated	Aug 13, 2013	Radiation Therapy Oncology Group	Trial would not be completed in a reasonable timeframe per CTEP guidelines	Other (stated, no rule matched)
NCT02345460	Preoperative Folfirinox for Resectable Pancreatic Adenocarcinoma - A Phase II Study	Phase 2	terminated	Jan 26, 2015	Case Comprehensive Cancer Center	Competing studies	Other (stated, no rule matched)
NCT02057874	3-Tesla MRI Response to TACE in HCC (Liver Cancer)	N/A	terminated	Feb 7, 2014	Vanderbilt-Ingram Cancer Center	Funding unavailable	Funding
NCT01197664	Paricalcitol, Fluorouracil, and Radiation Therapy in Treating Patients With Rectal Cancer…	Phase 1	terminated	Sep 9, 2010	Wake Forest University Health Sciences	Study terminated due to funding issues	Funding
NCT02423954	Study of Nivolumab Plus Chemotherapy in Patients With Advanced Cancer (NivoPlus)(NivoPlus)	Phase 1 / Phase 2	terminated	Apr 22, 2015	Western Regional Medical Center	Investigator no longer at site to enroll patients or write up data	Investigator
NCT00832637	Gemcitabine, Oxaliplatin, Tarceva &/or Cisplatin in HCC & Biliary Tree Cancers(Gem-ox)	Phase 2	terminated	Jan 30, 2009	New Mexico Cancer Research Alliance	Low accrual	Enrollment / accrual
NCT03168152	Randomized Trial Comparing Stereotactic Body Radiation Therapy to Microwave Ablation for…	N/A	withdrawn	May 30, 2017	University of Michigan Rogel Cancer Center	No patients were accrued to the trial	Enrollment / accrual
NCT02748161	DEB-TACE for Hepatocellular Carcinoma(QED)	N/A	terminated	Apr 22, 2016	Surefire Medical, Inc.	Low enrollment	Enrollment / accrual
NCT02702960	Sequential, Related Donor Partial Liver Transplantation Followed by Bone Marrow…	Phase 2	withdrawn	Mar 9, 2016	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	This study was withdrawn due to lack of necessary resources from the liver transplant surgical…	Other (stated, no rule matched)
NCT02690350	An Open Study Assessing the Safety and Tolerability of U3-1784	Phase 1	terminated	Feb 24, 2016	Daiichi Sankyo	Program discontinued for business reasons (not safety).	Safety / toxicity
NCT01259024	The LC Bead Trial; Transarterial Chemoembolization of Hepatocellular Carcinoma (HCC)With…	N/A	terminated	Dec 13, 2010	Washington University School of Medicine	inability to obtain CMS approval	Other (stated, no rule matched)
NCT01887509	Evaluation of Rectal Tumor Margin Using Confocal Endomicroscopy and Comparison to…(TRaMA)	N/A	terminated	Jun 27, 2013	IHU Strasbourg	Difficulties with patients recruitment, study acceptance and protocol implementation.	Enrollment / accrual
NCT00459108	Dasatinib in Treating Patients With Advanced Liver Cancer That Cannot Be Removed by…	Phase 2	terminated	Apr 11, 2007	National Cancer Institute (NCI)	Halted early for futility.	Efficacy / futility
NCT02149771	Combination Treatment for Advanced Liver Cancer	Phase 3	withdrawn	May 29, 2014	Shanghai Zhongshan Hospital	Insufficient funding	Funding
NCT02577588	Trial of Adoptive T Cell Therapy With Activated P53 Specific T Cells for Treatment of…(ATACC)	Phase 1	terminated	Oct 16, 2015	National Center for Tumor Diseases, Heidelberg	not feasible	Other (stated, no rule matched)
NCT02374489	A Phase II Trial of LDK378 in ROS1 and /or ALK Over-expressed Advanced Intrahepatic or…	Phase 2	terminated	Feb 27, 2015	National Health Research Institutes, Taiwan	ROS1 in IHC and gene rearrangement result can not match。No tumor response。	Other (stated, no rule matched)
NCT02638909	Study of Oral Ceritinib in Patients With ALK and ROS1 Activated Gastrointestinal…	Phase 2	terminated	Dec 23, 2015	Criterium, Inc.	Lack of Enrollment	Enrollment / accrual
NCT02365662	A Study Evaluating Safety and Pharmacokinetics of ABBV-221 in Subjects With Advanced…	Phase 1	terminated	Feb 19, 2015	AbbVie	Safety	Safety / toxicity
NCT01359007	FOLFIRINOX in Patients With Inoperable Pancreatic Cancer	Phase 2	terminated	May 24, 2011	University of Oklahoma	The principal investigator terminated the study due to inactivity and low enrollment	Investigator
NCT01627379	Cisplatin and 5-FU +/- Panitumumab for Patients With Nonresectable,Advanced or Metastatic…(POWER)	Phase 3	terminated	Jun 25, 2012	AIO-Studien-gGmbH	Sponsor decision due to recommendation of the IDMC.	Sponsor / business decision
NCT01710293	Intervention Protocol for Automated Point-of-Care Surveillance of Outpatient Delays in…(PACT CREATE 3)	N/A	withdrawn	Oct 19, 2012	VA Office of Research and Development	Unable to obtain data needed to run the RCT; project never began recruitment	Enrollment / accrual
NCT02110953	Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal…	Phase 1	terminated	Apr 10, 2014	Fox Chase Cancer Center	IRB study closure by investigator due to low enrollment	Investigator
NCT02105350	A Study of MEK162 With Gemcitabine and Oxaliplatin in Biliary Cancer	Phase 1	withdrawn	Apr 7, 2014	University Health Network, Toronto	Study was never initiated	Other (stated, no rule matched)
NCT02496832	A Study of Hypoxia Imaging in Advanced Pancreatic Cancer Patients Being Treated With…	N/A	withdrawn	Jul 14, 2015	University Health Network, Toronto	Study was never initiated	Other (stated, no rule matched)
NCT03081039	A Study of Cisplatin or Carboplatin With Gemcitabine Versus Gemcitabine Alone as Adjuvant…	Phase 3	withdrawn	Mar 15, 2017	University of Louisville	Competing study	Other (stated, no rule matched)
NCT00878215	Clinical Application of Image-Guided Liver Surgery	Phase 2	terminated	Apr 8, 2009	Washington University School of Medicine	The image-guidance system became commercially available	Other (stated, no rule matched)
NCT02119676	Study of Ruxolitinib in Colorectal Cancer Patients	Phase 2	terminated	Apr 22, 2014	Incyte Corporation	Substudy 1 was terminated for futility at interim analysis and Substudy 2 was terminated per…	Efficacy / futility
NCT02392377	Molecular Phenotyping in Predicting Response in Patients With Stage IB-III Esophageal…	Phase 2	terminated	Mar 19, 2015	Case Comprehensive Cancer Center	Slow accrual	Enrollment / accrual
NCT01934179	Telomere Length in Predicting Toxicity in Older Patients With Stage III-IV Colorectal…	—	terminated	Sep 4, 2013	Fox Chase Cancer Center	Low Accrual Rate	Enrollment / accrual
NCT01956864	Study of High-Dose Oral Vitamin D for the Prevention of Liver Cancer	Phase 1	withdrawn	Oct 8, 2013	Johns Hopkins University	PI transferred from Georgetown to Johns Hopkins University. No participants enrolled at either…	Enrollment / accrual
NCT01721174	Endoscopic Biliary Radiofrequency Ablation of Malignant Distal Common Bile Duct Strictures	N/A	terminated	Nov 5, 2012	Chinese University of Hong Kong	Poor recruitment	Enrollment / accrual
NCT02407561	Prospective Validation Study for the Proprietary Rectal and Anal Cancer Protein…	—	terminated	Apr 3, 2015	Castle Biosciences Incorporated	Futility - unable to secure sites and samples for participation	Efficacy / futility
NCT01729923	A Trial of Maintenance ADAPT Therapy With Capecitabine and Celecoxib in Patients With…(ADAPT)	Phase 2	terminated	Nov 20, 2012	University of Washington	Funding ended	Funding
NCT02908165	Randomized Phase II Trial of Chemoembolization and Sorafenib	Phase 2	withdrawn	Sep 20, 2016	Yale University	A future study will be taking place using the same patient population.	Other (stated, no rule matched)
NCT00848783	Irinotecan/Cisplatin, Potentially Curative Surgery With or Without Floxuridine, Followed…	Phase 2	terminated	Feb 20, 2009	NYU Langone Health	Due to slow accrual	Enrollment / accrual
NCT00955721	A Study of Combination of Gemcitabine, Oxaliplatin (GEMOX)-Sorafenib in Patients With…	Phase 1 / Phase 2	terminated	Aug 10, 2009	University of Miami	Lack of Funding	Funding
NCT01012362	Study of Pazopanib and Ixabepilone in Patients With Solid Tumors	Phase 1	terminated	Nov 13, 2009	Masonic Cancer Center, University of Minnesota	PI left institution.	Investigator
NCT03307941	Assessment of Metabolic & Path Response w/ RCT & ImT Before Surgery in Locally Advanced…(ARTEMIS-Eso)	Phase 1 / Phase 2	withdrawn	Oct 12, 2017	Jules Bordet Institute	Suspended collaboration with the company providing the study drug	Sponsor / business decision
NCT02406508	Sequential Melphalan for Use With Hepatic Delivery System Treatment Followed by Sorafenib…	Phase 2	withdrawn	Apr 2, 2015	Delcath Systems Inc.	No enrollment in the study	Enrollment / accrual
NCT00903396	Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy…	Phase 2	terminated	May 18, 2009	Alliance for Clinical Trials in Oncology	Slow accrual	Enrollment / accrual
NCT02549755	11C-acetate for Treatment Response After Radiotherapy for HCC	Phase 2	terminated	Sep 15, 2015	Justin Sims	Poor enrollment	Enrollment / accrual
NCT00003530	Antineoplaston Therapy in Treating Patients With Primary Liver Cancer	Phase 2	terminated	Jan 27, 2003	Burzynski Research Institute	Slow accrual	Enrollment / accrual
NCT02958163	Clinical Trial Comparing TACE With TACE + SABR in Stage BCLC B HCC (HepSTAR)(HepSTAR)	Phase 2	terminated	Nov 8, 2016	Cliniques universitaires Saint-Luc- Université Catholique de Louvain	lack of recruitment	Enrollment / accrual

Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.

Data updated 23 days agoSource updated Sep 11, 2018source: clinicaltrials

Terminated, withdrawn and suspended studies

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