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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
25 stopped studies mapped to Carcinomatosis and descendants · 92% state a reason
Over the 25 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT04034251 | Intraperitoneal and Intravenous Paclitaxel Chemotherapy With Oral Capecitabine for… | Phase 2 | terminated | Jul 26, 2019 | National Cancer Institute (NCI) | Scientific reprioritization. Closed per principal investigator discretion to prioritize enrollment… | Investigator |
| NCT04929015 | Peritoneal Carcinomatosis Leveraging ctDNA Guided Treatment in GI Cancer Study (PERICLES… | N/A | suspended | Jun 18, 2021 | Rutgers, The State University of New Jersey | Pending Protocol amendment | Other (stated, no rule matched) |
| NCT05159050 | Intraperitoneal Paclitaxel-loaded TPM for Treatment of Peritoneal Carcinomatosis | Phase 1 | terminated | Dec 15, 2021 | Carlos Chan | Drug supply issues | Drug supply |
| NCT03875144 | Treatment of Malignant Peritoneal Mesothelioma (MESOTIP)(MESOTIP) | Phase 2 | suspended | Mar 14, 2019 | Institut du Cancer de Montpellier - Val d'Aurelle | This decision was taken following the occurrence of three cases of serious and unexpected suspected… | Safety / toxicity |
| NCT04729348 | Pembrolizumab And Lenvatinib In Leptomeningeal Metastases | Phase 2 | terminated | Jan 28, 2021 | Massachusetts General Hospital | Planned interim analysis | Efficacy / futility |
| NCT00527410 | A Safety Study of RTA 744 in Recurrent, Progressive or Refractory Neoplastic Meningitis(LMD) | Phase 1 | terminated | Sep 10, 2007 | Biogen | Business Decision | Sponsor / business decision |
| NCT06365918 | Study of VG2025 Delivered Intraperitoneally in Patients With Advanced Solid Tumors With… | Phase 1 | withdrawn | Apr 15, 2024 | M.D. Anderson Cancer Center | PI Request | Other (stated, no rule matched) |
| NCT04665921 | A Study of SGN-STNV in Advanced Solid Tumors | Phase 1 | terminated | Dec 14, 2020 | Seagen Inc. | Study closed due to portfolio prioritization | Sponsor / business decision |
| NCT04583488 | Intraperitoneal Docetaxel in Combination With mFOLFOX6 for Gastric Cancer Patients With… | Phase 1 | terminated | Oct 12, 2020 | Johns Hopkins University | PI left institution | Investigator |
| NCT05687617 | Near-infrared Imaging With Indocyanine Green for Detection of Peritoneal Metastases for… | Phase 2 | terminated | Jan 18, 2023 | Laval University | Recruitment lower than expected and negative results. | Enrollment / accrual |
| NCT04826432 | Pasireotide to Reduce Clinically Relevant Digestive Leakage After Complete Cytoreductive…(PASIREOCHIP) | Phase 2 | terminated | Apr 1, 2021 | Gustave Roussy, Cancer Campus, Grand Paris | No more experimental drugs available | Other (stated, no rule matched) |
| NCT04047771 | A Phase I Study Evaluating SCB-313 for the Treatment of Subjects With Peritoneal… | Phase 1 | terminated | Aug 7, 2019 | Sichuan Clover Biopharmaceuticals, Inc. | terminated | Other (stated, no rule matched) |
| NCT04315246 | 177Lu-DTPA-Omburtamab Radioimmunotherapy for Leptomeningeal Metastasis From Solid Tumors… | Phase 1 / Phase 2 | withdrawn | Mar 19, 2020 | Y-mAbs Therapeutics | Business priorities | Sponsor / business decision |
| NCT03682744 | CAR-T Intraperitoneal Infusions for CEA-Expressing Adenocarcinoma Peritoneal Metastases… | Phase 1 | withdrawn | Sep 25, 2018 | Sorrento Therapeutics, Inc. | Unable to enroll subjects | Enrollment / accrual |
| NCT04232384 | Comparison of "Roll-over' Technique With Standard Abdominal Paracentesis in Suspected…(ROLLON) | N/A | terminated | Jan 18, 2020 | Post Graduate Institute of Medical Education and Research, Chandigarh | Recruitment slow due to COVID-19 | COVID-19 / pandemic |
| NCT04125225 | What Are the Experiences of Patients With Pseudomyxoma Peritonei? | — | withdrawn | Oct 14, 2019 | University of Southampton | No participants enrolled. | Enrollment / accrual |
| NCT02803515 | Hyperthermic Intraperitoneal Chemotherapy (HIPEC) : Predictive Marker and Mechanism | N/A | terminated | Jun 17, 2016 | Centre Hospitalier Universitaire de Nice | not stated | Not stated |
| NCT03150628 | Cytoreductive Surgery and Intraperitoneal Chemotherapy for Stomach CAncer: a Feasibility…(CISCA) | Phase 2 | terminated | May 12, 2017 | Richard van Hillegersberg | Conflicting recruitment with PERISCOPE II study (NCT03348150) | Enrollment / accrual |
| NCT01540344 | Combined Anticancer Treatment of Advanced Colon Cancer(COMBATAC) | Phase 2 | terminated | Feb 28, 2012 | University of Regensburg | Slow recruitment. | Enrollment / accrual |
| NCT01683864 | Randomized Controlled Trial to Prevent Peritoneal Seeding in Gastric Cancer(HIPECStomach) | Phase 2 / Phase 3 | terminated | Sep 12, 2012 | University Hospital Tuebingen | Recruitment problems | Enrollment / accrual |
| NCT01095523 | Prospective Randomized Trial Evaluating Mandatory Second Look Surgery With HIPEC and CRS… | Phase 2 | withdrawn | Mar 30, 2010 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01342653 | Clinical Trial at Neoadjuvant Peritoneal and Systemic Chemotherapy Plus HIPEC in Gastric…(HIPEC) | Phase 2 | suspended | Apr 27, 2011 | Hospital General Universitario Gregorio Marañon | unable to reach planned recruitment | Enrollment / accrual |
| NCT01116791 | Cytoreductive Surgery(CRS) Plus Hyperthermic Intraoperative Peritoneal Chemotherapy(HIPC)… | Phase 2 | terminated | May 5, 2010 | Baki Topal | Insufficient enrollment in Pancreatic \& Biliary arm | Enrollment / accrual |
| NCT00005812 | Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or… | Phase 2 | terminated | Jan 27, 2003 | Dartmouth-Hitchcock Medical Center | No objective response documented, protocol terminated after 12 patients. | Other (stated, no rule matched) |
| NCT01438021 | Continuous Intraventricular Methotrexate in Treating Patients With Leptomeningeal Disease | N/A | withdrawn | Sep 21, 2011 | City of Hope Medical Center | Lack of funding | Funding |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated May 5, 2026source: clinicaltrials