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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
556 stopped studies mapped to Acute Myeloid Leukemia and descendants · 90% state a reason
Over the 556 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT00279773 | Safety, Pharmacokinetics and Pharmacodynamics of TKI258 in Subjects With Acute Myeloid… | Phase 1 | terminated | Jan 20, 2006 | Novartis Pharmaceuticals | Study was stopped due to time dependent drug accumulation | Other (stated, no rule matched) |
| NCT00322673 | Study of XL999 in Patients With Acute Myeloid Leukemia (AML) | Phase 2 | terminated | May 8, 2006 | Symphony Evolution, Inc. | Study was terminated due to cardiac toxicities | Safety / toxicity |
| NCT00594555 | A Study Evaluating the Effects of CLAG With Gleevec in Refractory or Relapsed Acute… | Phase 2 | withdrawn | Jan 15, 2008 | University of Cincinnati | Principal Investigator resigned position with the University of Cincinnati, closing study at this… | Investigator |
| NCT00363025 | A Randomized Study of Post-Remission Therapy in Elderly Patients With Acute Myelogenous… | Phase 3 | terminated | Aug 15, 2006 | Acute Leukemia French Association | not stated | Not stated |
| NCT00104468 | Study of Troxatyl™ Administered by Continuous Infusion to Subjects With Refractory Acute… | Phase 1 / Phase 2 | terminated | Mar 1, 2005 | SGX Pharmaceuticals, Inc. | Trial stopped June 2007 | Other (stated, no rule matched) |
| NCT00329498 | L-Ascorbic Acid Depletion to Treat Acute Myeloid Leukemia and Myelodysplastic Syndromes | Phase 2 | suspended | May 24, 2006 | Samsung Medical Center | not stated | Not stated |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 22 days agoSource updated Jun 30, 2010source: clinicaltrials