Clinical trial · Observational
Cryoablation for Advanced and Refractory Desmoid Tumors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Desmoid tumors, also called aggressive fibromatosis, are rare, locally invasive tumors with no potential for metastasis. The incidence is approximately 2 to 4 per million per year in the general population. The "watch and wait" policy is the standard of care for newly diagnosed patients in Europe. Patients who progress have first-line medical treatment, surgery is no longer the treatment because there is a high rate of recurrence (\> 60%) and radiotherapy is not very suitable because the patients are often young and the tumors are large. Cryoablation seems to be an effective therapeutic option that should be evaluated.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Desmoid Tumors | Desmoid Fibromatosis | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Progression-free survival assessed using RECIST(Response evaluation criteria in solid tumors) criteria
- timeFrame
- at 6 months after cryoablation
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion criteria: * Adult patient (≥18 years old) * Having undergone cryoablation for an advanced desmoid tumor refractory to medical treatment * Having not expressed their opposition, after being informed, to the reuse of their data for the purposes of this research. Exclusion criteria: * Subject who expressed their opposition to participating in the study * Patient already included in another ongoing study * Subject under guardianship or curatorship * Subject under safeguard of justice
References
Publications (0)
Data not yet available