Ranking · Unmet Need

Trial Gap Ratio

log₂ of a cancer’s share of deaths divided by its share of active interventional trials, both computed over the eligible top-level cancers of the scope. 0 = trial share matches death share; +1 = twice as many deaths as trials would suggest; −1 = half. Scale-free, so it can be compared across scopes, unlike the percentile-based Trial Gap Index.

Computedci-trial-gap-ratio-v1unit: log₂ ratiohigher = worseAll metrics

Rank	Δ	Cancer	Trial Gap Ratio (log₂ ratio)	Percentile	Confidence	Sources	Why #n?
1	=	Malignant Colon Neoplasm	+2.72	100	High confidence	cdc-wonder clinicaltrials	inputs deaths 40801 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.074626 thresholds minDeaths 100 minActivity 1 trialShare 0.011322 activeTrials 225 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9322 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580336
2	=	Malignant Gallbladder Neoplasm	+2.32	97.1	High confidence	cdc-wonder clinicaltrials	inputs deaths 4402 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.008051 thresholds minDeaths 100 minActivity 1 trialShare 0.00161 activeTrials 32 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9574 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580337
3	=	Cutaneous Melanoma	+2.01	94.1	High confidence	cdc-wonder clinicaltrials	inputs deaths 8671 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.01586 thresholds minDeaths 100 minActivity 1 trialShare 0.003925 activeTrials 78 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9826 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580338
4	=	Malignant Laryngeal Neoplasm	+1.17	91.2	High confidence	cdc-wonder clinicaltrials	inputs deaths 4095 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.00749 thresholds minDeaths 100 minActivity 1 trialShare 0.003321 activeTrials 66 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9700 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580339
5	=	Malignant Pancreatic Neoplasm	+1.05	88.2	High confidence	cdc-wonder clinicaltrials	inputs deaths 51327 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.093879 thresholds minDeaths 100 minActivity 1 trialShare 0.045491 activeTrials 904 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9637 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580340
6	=	Malignant Bladder Neoplasm	+0.87	85.3	High confidence	cdc-wonder clinicaltrials	inputs deaths 17396 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.031818 thresholds minDeaths 100 minActivity 1 trialShare 0.017411 activeTrials 346 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 10702 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580341
7	=	Malignant Lung Neoplasm	+0.82	82.4	High confidence	cdc-wonder clinicaltrials	inputs deaths 128762 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.23551 thresholds minDeaths 100 minActivity 1 trialShare 0.133052 activeTrials 2644 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9763 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580342
8	=	Skin Carcinoma	+0.64	79.4	High confidence	cdc-wonder clinicaltrials	inputs deaths 5462 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.00999 thresholds minDeaths 100 minActivity 1 trialShare 0.006391 activeTrials 127 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9889 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580343
9	=	Malignant Lip and Oral Cavity Neoplasm	+0.4	76.5	High confidence	cdc-wonder clinicaltrials	inputs deaths 5424 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.009921 thresholds minDeaths 100 minActivity 1 trialShare 0.007498 activeTrials 149 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 8881 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580344
10	=	Malignant Rectal Neoplasm	+0.34	73.5	High confidence	cdc-wonder clinicaltrials	inputs deaths 13446 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.024593 thresholds minDeaths 100 minActivity 1 trialShare 0.019424 activeTrials 386 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9385 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580345
11	=	Malignant Liver Neoplasm	+0.29	70.6	High confidence	cdc-wonder clinicaltrials	inputs deaths 30532 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.055844 thresholds minDeaths 100 minActivity 1 trialShare 0.045592 activeTrials 906 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9511 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580346
12	=	Malignant Kidney Neoplasm	+0.29	67.6	High confidence	cdc-wonder clinicaltrials	inputs deaths 15215 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.027829 thresholds minDeaths 100 minActivity 1 trialShare 0.022796 activeTrials 453 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 10639 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580347
13	=	Malignant Esophageal Neoplasm	+0.19	64.7	High confidence	cdc-wonder clinicaltrials	inputs deaths 16274 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.029766 thresholds minDeaths 100 minActivity 1 trialShare 0.026067 activeTrials 518 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9196 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580348
14	=	Malignant Vulvar Neoplasm	+0.07	61.8	High confidence	cdc-wonder clinicaltrials	inputs deaths 1555 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.002844 thresholds minDeaths 100 minActivity 1 trialShare 0.002717 activeTrials 54 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 10135 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580349
15	=	Malignant Prostate Neoplasm	-0.12	58.8	High confidence	cdc-wonder clinicaltrials	inputs deaths 34815 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.063678 thresholds minDeaths 100 minActivity 1 trialShare 0.069193 activeTrials 1375 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 10513 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580350
16	=	Malignant Anal Neoplasm	-0.18	55.9	High confidence	cdc-wonder clinicaltrials	inputs deaths 1651 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.00302 thresholds minDeaths 100 minActivity 1 trialShare 0.003422 activeTrials 68 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9448 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580351
17	=	Malignant Oropharyngeal Neoplasm	-0.26	52.9	High confidence	cdc-wonder clinicaltrials	inputs deaths 3286 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.00601 thresholds minDeaths 100 minActivity 1 trialShare 0.007196 activeTrials 143 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9007 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580352
18	=	Malignant Central Nervous System Neoplasm	-0.29	50	High confidence	cdc-wonder clinicaltrials	inputs deaths 18523 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.033879 thresholds minDeaths 100 minActivity 1 trialShare 0.041415 activeTrials 823 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 10765 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580353
19	=	Malignant Mesothelioma	-0.32	47.1	High confidence	cdc-wonder clinicaltrials	inputs deaths 2114 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.003867 thresholds minDeaths 100 minActivity 1 trialShare 0.004831 activeTrials 96 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9952 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580354
20	=	Malignant Uterine Corpus Neoplasm	-0.39	44.1	High confidence	cdc-wonder clinicaltrials	inputs deaths 8608 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.015744 thresholds minDeaths 100 minActivity 1 trialShare 0.020682 activeTrials 411 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 10324 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580355
21	=	Malignant Salivary Gland Neoplasm	-0.56	41.2	High confidence	cdc-wonder clinicaltrials	inputs deaths 1173 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.002145 thresholds minDeaths 100 minActivity 1 trialShare 0.00317 activeTrials 63 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 8944 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580356
22	=	Malignant Ovarian Neoplasm	-0.57	38.2	High confidence	cdc-wonder clinicaltrials	inputs deaths 12654 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.023145 thresholds minDeaths 100 minActivity 1 trialShare 0.03442 activeTrials 684 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 10387 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580357
23	=	Malignant Gastric Neoplasm	-0.67	35.3	High confidence	cdc-wonder clinicaltrials	inputs deaths 11246 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.020569 thresholds minDeaths 100 minActivity 1 trialShare 0.03281 activeTrials 652 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9259 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580358
24	=	Malignant Breast Neoplasm	-0.72	32.4	High confidence	cdc-wonder clinicaltrials	inputs deaths 43897 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.080289 thresholds minDeaths 100 minActivity 1 trialShare 0.132196 activeTrials 2627 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 10072 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580359
25	=	Multiple Myeloma	-0.9	29.4	High confidence	cdc-wonder clinicaltrials	inputs deaths 11967 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.021888 thresholds minDeaths 100 minActivity 1 trialShare 0.040962 activeTrials 814 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 11017 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580360
26	=	Malignant Vaginal Neoplasm	-0.97	26.5	Medium confidence	cdc-wonder clinicaltrials	inputs deaths 435 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.000796 thresholds minDeaths 100 minActivity 1 trialShare 0.00156 activeTrials 31 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 10198 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580361
27	=	Leukemia	-1.04	23.5	High confidence	cdc-wonder clinicaltrials	inputs deaths 23740 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.043421 thresholds minDeaths 100 minActivity 1 trialShare 0.08902 activeTrials 1769 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 11080 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580362
28	=	Malignant Thyroid Gland Neoplasm	-1.12	20.6	High confidence	cdc-wonder clinicaltrials	inputs deaths 2229 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.004077 thresholds minDeaths 100 minActivity 1 trialShare 0.008857 activeTrials 176 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 10828 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580363
29	=	Malignant Testicular Neoplasm	-1.36	17.6	Medium confidence	cdc-wonder clinicaltrials	inputs deaths 462 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.000845 thresholds minDeaths 100 minActivity 1 trialShare 0.002164 activeTrials 43 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 10576 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580364
30	=	Malignant Penile Neoplasm	-1.51	14.7	Medium confidence	cdc-wonder clinicaltrials	inputs deaths 415 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.000759 thresholds minDeaths 100 minActivity 1 trialShare 0.002164 activeTrials 43 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 10450 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580365
31	=	Malignant Hypopharyngeal Neoplasm	-1.55	11.8	Medium confidence	cdc-wonder clinicaltrials	inputs deaths 498 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.000911 thresholds minDeaths 100 minActivity 1 trialShare 0.002667 activeTrials 53 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9133 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580366
32	=	Non-Hodgkin Lymphoma	-1.59	8.8	High confidence	cdc-wonder clinicaltrials	inputs deaths 19882 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.036365 thresholds minDeaths 100 minActivity 1 trialShare 0.109098 activeTrials 2168 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 10954 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580367
33	=	Malignant Cervical Neoplasm	-1.72	5.9	High confidence	cdc-wonder clinicaltrials	inputs deaths 4207 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.007695 thresholds minDeaths 100 minActivity 1 trialShare 0.025413 activeTrials 505 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 10261 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580368
34	=	Hodgkin Lymphoma	-2.44	2.9	Medium confidence	cdc-wonder clinicaltrials	inputs deaths 909 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.001663 thresholds minDeaths 100 minActivity 1 trialShare 0.009008 activeTrials 179 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 10891 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580369
35	=	Malignant Nasopharyngeal Neoplasm	-3.43	0	Medium confidence	cdc-wonder clinicaltrials	inputs deaths 664 formula log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1) sumDeaths 546737 deathShare 0.001214 thresholds minDeaths 100 minActivity 1 trialShare 0.013134 activeTrials 261 burdenSourceId CI-SOURCE-00000011 sumActiveTrials 19872 eligibleEntities 35 countersComputedAt 2026-09-29 02:00:20.557824-04 mortalityObservationId 9070 componentsFormulaVersion ci-research-gap-components-v1 ranking row 2580370

Data updated 16 hours agoSource updated unknown35 eligible entities · inputs hash e52171cf876028dd79f9840c

Methodology

How this table was built

Formula: log2( (deaths / Σ deaths) / (active_trials / Σ active_trials) ) over eligible top-level cancers (deaths ≥ 100, active_trials ≥ 1)
Version: ci-trial-gap-ratio-v1
Scope: USA · both sexes · all ages · 2024 · top-level cancers
Scope key: geo=USA|sex=all|age=all|year=2024|level=top
Eligible entities: 35
Generated: Sep 29, 2026, 06:16 AM UTC
Inputs hash: e52171cf876028dd79f9840c
Sources: CDC WONDER — Underlying Cause of Death (US mortality by ICD-10 site)ClinicalTrials.gov
Aggregation: none

Eligibility

requires: mortality_count
active_trials
minDeaths: 100
entityLevel: top

Full methodology · ties share a rank (1, 2, 2, 4) · previous rank refers to the last snapshot of the same scope.

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