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The NSDHL/c-Myc/PKM2 Axis Drives Glycolytic Reprogramming and Tumor Growth in Multiple Myeloma.

Can Yue, Bei-Hui Huang, Lin Qi, Xing-Ding Zhang, Juan Li

International journal of molecular sciencesSep 16, 2026PMID 42794667doi:10.3390/ijms27188239 PMC13607027Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 29, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260929-000001
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Multiple myeloma (MM) remains largely incurable because of its complex biology and frequent disease relapse. Metabolic reprogramming is increasingly recognized as a critical contributor to MM progression. NAD (P)-dependent steroid dehydrogenase-like protein (NSDHL) has been highlighted as an…

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