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Anti-CD38 monoclonal antibodies in multiple myeloma and beyond: immunotherapeutic mechanisms, evidence maturity, and clinical positioning.

Liming Yu, Changnian Li, Dadong Guo, Siyuan Cui

Frontiers in immunologyJan 1, 2026PMID 42746158doi:10.3389/fimmu.2026.1932951 PMC13575964Journal ArticleReviewpubmedProvenance
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PubMed
Retrieved
Sep 29, 2026
Layer
normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260929-000001
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Anti-CD38 monoclonal antibodies have become a central immunotherapeutic platform in multiple myeloma, where they have reshaped treatment across relapsed or refractory disease, frontline therapy, maintenance intensification, and minimal residual disease-oriented management. Their success in multiple…

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