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Economic advantage of daratumumab, bortezomib, lenalidomide, and dexamethasone vs bortezomib, lenalidomide, and dexamethasone for transplant-ineligible or transplant-deferred newly diagnosed multiple myeloma: A cost-per-responder evaluation.

Santosh Gautam, Laura Morrison, Philippe Thompson-Leduc, Avani Samandur, Brian Macomson, Vipin Khare, Xin Yin, Rohan Medhekar

Journal of managed care & specialty pharmacyOct 1, 2026PMID 42726291doi:10.18553/jmcp.2026.26127 Journal ArticleComparative StudyClinical Trial, Phase IIIpubmedProvenance
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PubMed
Retrieved
Sep 30, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260930-000001
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BACKGROUND: In the phase III CEPHEUS trial, 8 cycles of daratumumab (D), bortezomib (V), lenalidomide (R), and dexamethasone (d) followed by monthly DRd were associated with a higher rate of minimal residual disease (MRD) negativity compared with VRd followed by Rd among patients with…

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