Publication
Myeloma engraftment suppresses osteocytic ossification signatures rescued by loading in mice and reveals predictors of patient outcome.
Fani Ziouti, Muhammad Azeem, Maximilian Rummler, Maciej Rosolowski, Gerardo Zapata, Wyonna Rindt, Catherine Julien, Josephine T Tauer, Wen-Hui Cheng, Susanne Beck, Anja Seckinger, Dirk Hose, Ellen Leich, Bjarne Bogen, Maureen E Lynch, Martin Kuric, Melanie Krug, Regina Ebert, Frank Zaucke, Franz Jakob, Bettina M Willie, Franziska Jundt
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- PubMed
- Retrieved
- Sep 8, 2026
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- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260908-000002
Abstract
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Multiple myeloma (MM) is a malignant plasma cell disease inducing osteolytic lesions by disrupting bone homeostasis, fostering catabolic and suppressing anabolic functions. While the impact on osteoblast generation and function is well documented, alterations of osteocyte function and extracellular…
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Candidate 1
- cancerMultiple Myelomadictionary0.60
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