Publication
Activating a novel cell death pathway to target PI-resistant multiple myeloma and enhance immunogenic cell death.
Xinyun Zhang, Zhiming Wang, Yilei Shi, Qi Li, Si Chen, Lexin He, Yali Chai, Hao Xu, Yuchen Zhang, Meifang Zhao, Wenzhuo Zhuang, Bingzong Li
- Source
- PubMed
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260929-000001
Abstract
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Resistance to proteasome inhibitors (PIs) and inadequate engagement of anti-tumor immunity remain major barriers to effective treatment of multiple myeloma (MM). Here, we identified anwulignan, a bioactive natural product, as a translationally promising agent that retains activity in PI-resistant…
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Candidate 1
- cancerMultiple Myelomadictionary0.60
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