Publication
Machine Learning and Molecular Modeling Reveal HDAC6 as a Key Target of Tanshinone IIA in Multiple Myeloma.
Jian Gao, Jiawen Chu, Pengpeng Li
The journal of physical chemistry. BSep 3, 2026PMID 42691419doi:10.1021/acs.jpcb.6c03788 Journal ArticlepubmedProvenance
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- Sep 30, 2026
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Abstract
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Multiple myeloma (MM) is a malignant blood cancer marked by severe bone destruction and immune microenvironment disruption. Yet relapse and drug resistance remain major clinical challenges. Tanshinone IIA (TIIA) exhibits potent antitumor activity, but its molecular targets and mechanisms in MM…
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- cancerMultiple Myelomadictionary0.60
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