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A single-cell atlas of multiple myeloma defines malignant archetypes and proliferative states.

Mor Zada, Anna Kurilovich, Noam Shapira, Shuang-Yin Wang, Reut Sharet-Eshed, Shlomit Kfir-Erenfeld, Miriam Schlossberg, Elina Zorde, Nathalie Asherie, Chamutal Gur, Paulina Chalan, Rotem Shalita, Maya Ben Yehuda, Pascale Zwicky, Michelle von Locquenghien, Florian Ingelfinger, Kfir Mazuz, Eyal David, Anna Gurevich-Shapiro, Natan Melamed, Iuliana Vaxman, Irit Avivi, Assaf Weiner, Polina Stepensky, Yael Cohen, Ido Amit

Nature geneticsSep 1, 2026PMID 42680839doi:10.1038/s41588-026-02725-5 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 19, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
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Multiple myeloma (MM) is a plasma-cell malignancy with extensive genomic and transcriptional heterogeneity, limiting disease classification and precision therapy. Here we generated a clinically annotated, population-scale, single-cell atlas of MM from 341 individuals spanning the disease and…

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