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Cardiovascular disease and amyloidosis in phase III multiple myeloma trials: a systematic review of eligibility, screening and event reporting.

Oliver Henriques Peck, Aimee McCoubrey, John A Snowden, Ashutosh Wechalekar, Jennifer Travers, Jennifer S Lees, Mark C Petrie, Ninian N Lang

Open heartSep 1, 2026PMID 42680232doi:10.1136/openhrt-2026-004240 PMC13536086Journal ArticleSystematic ReviewpubmedProvenance
Source
PubMed
Retrieved
Sep 19, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
Published

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BACKGROUND: Cardiovascular disease (CVD) and light chain (AL) amyloidosis are important causes of morbidity and mortality in patients with multiple myeloma (MM). Additionally, MM therapies can have cardiovascular effects. However, the extent to which phase III MM trials account for underlying CVD…

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