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CD19 CAR T-cell therapy (GLPG5101) for relapsed or refractory B-cell non-Hodgkin lymphoma (ATALANTA-1): phase 1 results from a single-arm, multicentre, phase 1/2 study.

Marie José Kersten, Maria T Kuipers, Pim G N J Mutsaers, Evelyne Willems, Kirsten Saevels, Martin Dreyling, Caron Jacobson, Michael R Bishop, Maarten Zandvliet, Stavros Milatos, Chiara Lobetti-Bodoni, Sandra Blum, Kirsten Van Hoorde, Jigar Desai, Lorenzo Acciarri, Margot J Pont, Anna van Muyden, Omotayo Fasan, Joost S P Vermaat, Sébastien Anguille

The Lancet. HaematologySep 1, 2026PMID 42660131doi:10.1016/S2352-3026(26)00192-4 Journal ArticleMulticenter StudyClinical Trial, Phase IClinical Trial, Phase IIpubmedProvenance
Source
PubMed
Retrieved
Sep 17, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260917-000001
Published

Abstract

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BACKGROUND: Chimeric antigen receptor (CAR) T-cell therapies have transformed the treatment of B-cell non-Hodgkin lymphoma, but centralised manufacturing-with its complex logistics and long vein-to-vein times-drives up costs and restricts access. We aimed to evaluate the safety of GLPG5101, a…

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Validated 1

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Registered trialsNCT06561425

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