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Targeting metabolic reprogramming and epigenetic remodeling: a novel strategy to reshape the immune microenvironment in multiple myeloma.

Mingjie Wang, Le Wang, Jiapei Yuan

International immunopharmacologyOct 1, 2026PMID 42468165doi:10.1016/j.intimp.2026.117143 Journal ArticleReviewpubmedProvenance
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PubMed
Retrieved
Oct 1, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20261001-000001
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Multiple myeloma (MM) is a highly debilitating hematologic malignancy with a significant risk of mortality, now entering an era of comprehensive treatment. However, immune resistance remains the primary obstacle limiting long-term survival and effective treatment in patients. Two critical tumor…

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