Publication
Triptonide enhances DNA damage by inhibiting TRIP13‑mediated DNA repair and synergizes with bortezomib to suppress multiple myeloma.
Fen He, Junjun Li, Lijun Peng, Hongyan Zhao, Maoyou Lu, Ruixin Gao, Siqi Wang, Yu Chen, Ruihan Tang, Zhengguo Li, Linlin Zhang, Xinyu Zhang, Qianhao Li, Weihui Chen, Jiayu Liu, Cong Luo, Xi Zeng, Jiliang Xia
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- PubMed
- Retrieved
- Sep 15, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260915-000001
Abstract
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Multiple myeloma (MM) is a malignant disorder of plasma cells. Combinations of bortezomib (BTZ) with other therapeutic agents remain the mainstay of MM treatment. However, the rising incidence of drug resistance among patients with MM underscores an urgent need for novel therapeutic strategies. The…
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- cancerMultiple Myelomadictionary0.60
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