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Bone Marrow Microenvironment Drives Mature Neutrophil to a CD83 + Pro-Tumor State in Multiple Myeloma.

Yuan Meng, Fengyu Chen, Siyuan Chen, Yanling Xu, Ya Tan, Hongyan Liao, Qin Zheng

International journal of cancerOct 1, 2026PMID 42449498doi:10.1002/ijc.70651 PMC13432176Journal ArticlepubmedProvenance
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PubMed
Retrieved
Oct 1, 2026
Layer
normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20261001-000001
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Neutrophils are the most abundant immune cells in bone marrow (BM); their differentiation, maturation, and clearance are tightly regulated by the BM microenvironment. Multiple myeloma (MM) is a malignant plasma cell disorder that leads to multi-organ damage, including BM disruption, which may…

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