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Clinical course, risk factors, and therapeutic response in multiple myeloma with central nervous system involvement.

Alexander Xiao, Saurabh Zanwar, Yi Lin, Prashant Kapoor, Nadine Abdallah, Francis K Buadi, Moritz Binder, Angela Dispenzieri, David Dingli, Morie A Gertz, Wilson Gonsalves, Suzanne R Hayman, Taxiarchis Kourelis, Nelson Leung, Eli Muchtar, Mustaqeem Siddiqui, Melinda Tan, Rahma Warsame, S Vincent Rajkumar, Shaji Kumar

Blood advancesSep 8, 2026PMID 42348786doi:10.1182/bloodadvances.2026020668 PMC13543945Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 29, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260929-000001
Published

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Extramedullary disease (EMD) is increasingly recognized in relapsed/refractory multiple myeloma (MM), with central nervous system involvement (CNS-MM) representing a rare but highly aggressive manifestation associated with dismal outcomes. Data on its incidence and optimal management, particularly…

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