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Calpain-2 inhibition alleviates hypercalcemia-driven multiple myeloma progression.

Zeyuan Wang, Chaoying Yang, Yanpeng Wang, Zhiming Guo, Ruibo Jin, Ling Xiao, Jing Liu, Hui Zhou, Xiaojuan Xiao, Xu Han

Biochemical pharmacologySep 1, 2026PMID 42315074doi:10.1016/j.bcp.2026.118174 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 13, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260913-000001
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Multiple myeloma (MM) is a malignant hematological disorder characterized by the neoplastic proliferation of plasma cells. Hypercalcemia is a common complication in MM and is often considered a secondary consequence of disease progression. When calcium levels are severely elevated, it can lead to…

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