Publication
PKMYT1 is a targetable vulnerability in del(17p) high-risk multiple myeloma.
Anaïs Schavgoulidze, Jian Cui, Jessica Encinas Mayoral, Vanessa Favasuli, Srikanth Talluri, Sabrina Maheo, Chloé Cerutti, Masood Shammas, Daniel Primo, Carmen Vicente, Marta Larrayoz, José A Martínez-Climent, Kenneth C Anderson, Anil Aktas-Samur, Mehmet Kemal Samur, Hervé Avet-Loiseau, Jill Corre, Nikhil C Munshi, Mariateresa Fulciniti
- Source
- PubMed
- Retrieved
- Sep 30, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260930-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Deletion of chromosome 17p [del(17p)] is among the most adverse cytogenetic abnormalities in multiple myeloma (MM). By integrating RNA sequencing data from cells of patients with MM with genetic dependency data from MM cell lines, we identified protein kinase membrane-associated tyrosine/threonine…
Read on PubMedLinked entities
Linked entities (1)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Candidate 1
- cancerMultiple Myelomadictionary0.60
Curated evidence
Evidence citing this paper (0)
Data not yet available