Publication
Integrated Genomic and Epigenomic Analysis Reveals Epigenetic Plasticity in Disease Progression and Multidrug Resistance in Multiple Myeloma.
Rafael R Canevarolo, Praneeth Reddy Sudalagunta, Mark B Meads, Maria Silva, Xiaohong Zhao, Dario Magaletti, Raghunandan Reddy Alugubelli, Gabriel DeAvila, Daniel DeAvila, Erez Persi, Francesco Maura, Elissa T Bell, Ryan T Bishop, Christopher L Cubitt, Samer S Sansil, Wei Zhang, Jamie K Teer, Mingxiang Teng, Sean J Yoder, Erin M Siegel, Bijal D Shah, Taiga Nishihori, Lori Hazlehurst, Conor C Lynch, Ola Landgren, Oliver Hampton, Robert A Gatenby, Daniel M Sullivan, Jason Brayer, William Dalton, John L Cleveland, Melissa Alsina, Rachid Baz, Kenneth H Shain, Ariosto S Silva
- Source
- PubMed
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260929-000001
Abstract
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UNLABELLED: Multiple myeloma is marked by recurrent cytogenetic abnormalities and mutations that accumulate as the disease progresses. In this study, we sought to elucidate the transitions driving tumorigenesis and therapy resistance in multiple myeloma using a unique cohort of nearly 900 patients…
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Candidate 1
- cancerMultiple Myelomadictionary0.60
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