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Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma.

Maria-Cynthia Fuentes-Lacouture, Devi Nandana, Karthik Ramasamy, Anjan Thakurta

The FEBS journalSep 1, 2026PMID 42165697doi:10.1111/febs.70599 PMC13534934Journal ArticleReviewpubmedProvenance
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PubMed
Retrieved
Sep 9, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260909-000004
Published

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Immunomodulatory drugs (IMiDs), including lenalidomide and pomalidomide in combination with proteasome inhibitors, dexamethasone and anti-CD38 monoclonal antibodies, play a central role in the treatment of multiple myeloma (MM) across newly diagnosed and relapsed stages. These treatment regimens…

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