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Genomic landscape of locally advanced rectal adenocarcinoma: Comparison between before and after neoadjuvant chemoradiation and effects of genetic biomarkers on clinical outcomes and tumor response.

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Cancer Med2023PMID 37260182PMC10417181stubpubmedProvenance
Source
PubMed
Retrieved
Sep 10, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-CIVIC-20260910-000001
Published

Abstract

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Linked entities

Linked entities (2)

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Validated 2

Curated evidence

Evidence citing this paper (1)

civicProvenance
Source
CIViC — Clinical Interpretation of Variants in Cancer
Dataset
CIViC evidence items
Version
civic-2026-09-08
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Evidence
expert curation
License
CC0 1.0
PMID
37260182
Run
ING-CIVIC-20260908-000001
Open at source
CuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.
TherapyCancerTypeLevelDirection · significanceRating (1–5)StatusEvidenceSource
High1
(prognostic)Rectal AdenocarcinomaALIASPrognosticBSupports Poor Outcome3accepted
EID13211

This study evaluated genomic biomarkers associated with treatment response and clinical outcomes in patients with locally advanced rectal adenocarcinoma (LARC) treated with neoadjuvant chemoradiation … (full text at CIViC)

PMID 37260182 · Lee et al., 2023 · Open in CIViC

civic