Publication

Clinical characteristics and outcomes of B-cell precursor ALL with MEF2D rearrangements: a retrospective study by the Ponte di Legno Childhood ALL Working Group.

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Leukemia2023PMID 36309560PMC9883149stubpubmedPublished

Abstract

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Linked entities

Linked entities (2)

How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.

Validated 2

geneMEF2Dcivic_curation1.00
variantMEF2D Fusioncivic_curation1.00

Curated evidence

Evidence citing this paper (2)

civicCuratedShowing 1–2 of 2 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
BCL9 Fusion1
(prognostic)	B Lymphoblastic Leukemia/LymphomaCURATED_BROADER	Prognostic	B	Supports Poor Outcome	3	submitted	EID12177 This study was an international, multi-center retrospective analysis of 107 patients with MEF2D rearrangements, with information collected from 14 different regional study groups. The aim was to asses… (full text at CIViC) PMID 36309560 · Ohki et al., 2023 · Open in CIViC	civic
MEF2D Fusion1
(diagnostic)	B-lymphoblastic Leukemia With MEF2D RearrangementUNRESOLVED	Diagnostic	B	Supports Positive	3	accepted	EID12176 This international, multi-center retrospective analysis examined characteristics of 107 cases of B- lymphoblastic leukemia (B-ALL) with MEF2D gene rearrangements (MEF2D-r), gathering information from… (full text at CIViC) PMID 36309560 · Ohki et al., 2023 · Open in CIViC	civic